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60 Cards in this Set

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1st generation penicillins formulations
G (parenteral)
V (Oral)
Used to slow down the elimination of penicillin
Penicillin G salts
Benzathine
Procaine
Slows down absorption
First generation penicillin coverage
GAS,
Strep Viridans,
Strep pneumo,
Staph,
Enterococcus
Neiserria meng.
Clostridium
Syphillus
2nd generation penicillins
Oxacillin
Nafcillin
Cloxacillin
Dicloxacillin
Dicloxacillin
Dycill
Dynapen
2nd generation penicillins
two chloride
250-500mg po q6h
Cloxacillin
Cloxapen
one chloride
250-500mg po q6h
Oxacillin
Prostaphlin
Bactocill
1-2g po IM IV q 4-6 hours
2nd generation penicillins coverage
MSSA
Strep Viridans
No G(-)
No enterococci
Nafcillin
Nafcill
Unipen
2nd generation penicillin
1-2g IV IM q 4-6 hrs
Penicillin G
Pfizerpen
2-4 million units q4h
Penicillin G procaine
Wycillin
300,000-600,000 Units/day
Penicillin G Benzathine
Bicillin LA
1.2 million units for strep throat
2.4 million units for syphillis
Pen-Vee-K
Veetids
Penicillin V
250-500mg po bid-qid
Omipen
Principen
Ampicillin
3rd generation penicillin
1-2g IV IM po q4-6hrs
Amoxil
Trimox
Moxatag
Amoxicillin
3rd generation penicillin
250-500mg po q8h
775mg (ER) po q24h
3rd generation penicillin coverage
Strep Viridans
Staph aureus
Enterococcus (IV AMP)
Listeria (IV AMP)
Salmonella
Shigella
H. influenza
E. coli
Proteus
4th generation penicllins
Piperacillin
Ticarcillin
Pipracil
Piperacillin
Piperacillin coverage
Strep group
Strep viridans
Enterococcus
Salmonllea
Shigella
H. Influenza
E.coli
Enterobacteracie
Proteus
Pseudamonas
Ticarcillin coverage
Marginal G (+)
Salmonella
Shigella
E.coli
Enterobacteraciae
Proteus
Pseudamonas (weak)
Augmentin
Amoxicillin Clavulanic Acid
250-500mg po tid
500-875mg po bid
Extra coverage of anaerobes (bites)
Unasyn
Ampicillin Sulbactam
1.5-3g IV q6-8hr
Extra coverage for anaerobes
Zosyn
Piperacillin tazobactam
4.5g IV q6h
Timentin
ticarcillin clavulanic acid
3.1g IV q4-6h
SE of beta-lactams
rash
GI upset
C. difficle
Neutropenia

Hepatitis:
Nafcillin
Oxacillin
DDI of beta-lactams
probenecid can increase half-life
beta-lactam distribution
all over the body except the prostate and eye
beta-lactam absorption
poor GI bioavailability
Cefadroxil
Duricef
Ultracef
1st generation cephalosporin
1-2g po in 1-2 divided doses
1st generation cephalosporin
Cefadroxil
Cefazolin
Cephalexin
1st generation cephalosporin coverage
Staph aureus
Strep group
Strep viridans
Proteus
E. Coli
Klebsiella
Ancef
Cefazolin
1st generation cephalosporin
250-1000mg IV q8h
Keflex
Cephalexin
1st generation cephalosporin
250-500mg po q6h
2nd generation cephalosporin coverage
Staph aureus
Strep (but weaker than 1st)
H. influ
Enterobacter
Neiserria gon.
Proteus
E. coli
Klebsiella
Ceclor
Cefaclor
250-500mg po q8hr
Cefotan
Cefotetan
2nd generation
1-2g q12h IM IV. Has coverage against B. fragilis. Has MTT side-chain
Mefoxin
Cefoxitin
2nd generation
1-2 g q6-8hr IV. Has anaerobic coverage
Cefzil
Cefprozil
250-500mg po q12-24h. Has anaerobic activity.
Ceftin
Zinacef
Cefuroxime
750-1500mg q8h IV IM
Crosses BBB
3rd generation cephalosporin coverage
S. aureus (but 1st generation best)
All Strep
H. influenza
Enterobacter
N. gon
Proteus
E. coli
Klebsiella
Serratia
Omnicef
Cefdinir
3rd generation
300mg po q12h
Suprax
Cefixime
3rd generation
400mg/d
Claforan
Cefotaxime
Good for Strep pn.
Crosses BBB.
1-2g IV q6-8h
Vantin
Cefpodoxime
Has anaerobic coverage
100-400mg po q12h
Fortaz,
Tazicef
Ceftazidime
1-2g IV IM q8-12h.
Crosses BBB
Has Antipseudamonal activity.
Cedax
Ceftibuten
3rd generation cephalosporin
400mg/d po
Rocephin
Ceftriaxone
3rd generation cephalosporin
1-2g/d IV IM
Crosses BBB.
Good activity against Strep. pna
Maxipime
Cefepime
1-2g q12h
Good BBB penetration
Good Strep and Staph
Antipseudamonal activity
Azactam
Aztreonam
1-2g q8-12h
Cayston
Aztreonam Nebulizer
75mg inhaled tid
Carbapenams
Imipenem
Ertapenem
Meropenem
Carbapenam coverage
Staph aureus
Strep
HENPEKS
B. fragilis
Providencia
Pseudomonas
Acinetobacter
Citrobacter
Primaxin
Impenem-Cilastatin
0.5g IV IM q6-8h
Does cover E. facealis
Don't give for meningitis because of seizure risk.
Merrem
Meropenem
500-2000mg IV q8h
Nausea
Intraabdominal infections: Strep viridans, E.coli, Pseudamonas, Bacteriodes
Invanz
Ertapenem
1g IV IM q24h
Doribax
Doripenem
500mg IV q8h.
Less CNS tox. reserved for meningitis and peds along with meropenem
Macrolides coverage
G+
C>A>E
MSSA
Strep pna
group viridans strep
Bacillus
Corynebacterium

G (-)
A>C>E
H. influ (not E)
M. catarrhallis
Neiserria (azithro)

Effective against upper respiratory anaerobes

Atypicals
Legionella (A)
Chlamydia
Mycoplasma
U. urelyticum

Syphillis
Campylobacter
Bordetella
Pasteurella
Zithromax
Azithromycin
250mg/d IV po
Can cover Legionella and Neiserria gon.
1g for Chlamydia (long half-life)
can cause epidermal necrolysis
Used to prevent MAC in AIDS
Biaxin
Clarithromycin
250mg po bid
Used in tx or ppx of MAC
Used in H. pylori
Can cause C. difficle
Need to be dose adjusted for CrCl <30

Erythromycin
250-500mg PO q6h
estolate can cause hepatitis
motility agent and can cause N/V/D
Ototoxic at high doses
QT prolongation
safe in pregnancy
P450 inhibitor