Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
113 Cards in this Set
- Front
- Back
name 5 classes of antibiotics
|
1.aminoglycosides 2.cephalosporins 3.quinolones/fluroquinolones 4.vancomycin 5.macrolides
|
|
how antibiotics work
|
1.protein synthesis 2.nucleic acid 3.cell wall 4.cell membrane 5.metabolic reactions
|
|
problems with antibiotics
|
1.resistance 2.superinfection 3.anaphylaxis 4.toxicity 5.ab's in food supply
|
|
sulfonamides (examples)
|
sulfanilamide sulfamethoxazole
|
|
isoniazid (examples)
|
none
|
|
metronidazole (examples)
|
none
|
|
chloroquine (examples)
|
primaquine
|
|
fluoroquinolones (examples)
|
ciprofloxacin enoxacin
|
|
penicillins (examples)
|
penicillin-G ampicillin amoxicillin nafcillin oxacillin
|
|
cephalosporins (examples)
|
cephalothin cephalexin
|
|
aminoglycosides (examples)
|
gentamicin neomycin amikacin streptomycin
|
|
chloramphenicol (examples)
|
none
|
|
tetracyclines (examples)
|
chlortetracycline oxytetracycline doxycycline minocycline
|
|
macrolides (examples)
|
erythromycin clarithromycin azithromycin
|
|
vancomycin (examples)
|
none
|
|
rifampin (examples)
|
rifapentine
|
|
clindamycin (examples)
|
lincomycin
|
|
bacitracin (examples)
|
none
|
|
polymyxin (examples)
|
none
|
|
spectinomycin (examples)
|
none
|
|
moxalactam (examples)
|
imipenem
|
|
nystatin (examples)
|
none
|
|
griseofulvin (examples)
|
none
|
|
amphotericin B (examples)
|
none
|
|
imidazoles (examples)
|
clotrimazole ketoconazole
|
|
sulfonamides (source)
|
synthetic
|
|
isoniazid (source)
|
synthetic
|
|
metronidazole (source)
|
synthetic
|
|
chloroquine (source)
|
synthetic
|
|
fluoroquinolones (source)
|
synthetic
|
|
penicillins (source)
|
penicillium notatum penicillium chrysogenum synthetic semisynthetic
|
|
cephalosporins (source)
|
cephalosporium semisynthetic
|
|
aminoglycosides (source)
|
micromonospora species streptomyces species
|
|
chloramphenicol (source)
|
streptomyces venezuelae
|
|
tetracyclines (source)
|
streptomyces species semisynthetic
|
|
macrolides (source)
|
streptomyces erythraeus semisynthetic
|
|
vancomycin (source)
|
streptomyces orientalis
|
|
rifampin (source)
|
streptomyces mediterranei semisynthetic
|
|
clindamycin (source)
|
streptomyces lincolnesis
|
|
bacitracin (source)
|
bacillus subtilis
|
|
polymyxin (source)
|
bacillus polymyxa
|
|
spectinomycin (source)
|
streptomyces spectabilis
|
|
moxalactam (source)
|
chromobacter violaceum
|
|
nystatin (source)
|
streptomyces noursei
|
|
griseofulvin (source)
|
penicillium janczewski
|
|
amphotericin B (source)
|
streptomyces nodosus
|
|
imidazoles (source)
|
synthetic
|
|
sulfonamides (spectrum)
|
broad
|
|
isoniazid (spectrum)
|
tubercle bacilli
|
|
metronidazole (spectrum)
|
trichomonas vaginalis
|
|
chloroquine (spectrum)
|
plasmodium species
|
|
fluoroquinolones (spectrum)
|
broad
|
|
penicillins (spectrum)
|
broad (esp gram+)
|
|
cephalosporins (spectrum)
|
broad (esp gram+)
|
|
aminoglycosides (spectrum)
|
broad (esp gram-)
|
|
chloramphenicol (spectrum)
|
broad (esp typhoid bacilli)
|
|
tetracyclines (spectrum)
|
broad (rickettsiae, chlamydiae, gram-)
|
|
macrolides (spectrum)
|
broad (mycoplasma gram+)
|
|
vancomycin (spectrum)
|
gram+ (esp staphylococci)
|
|
rifampin (spectrum)
|
tubercle bacilli (gram-)
|
|
clindamycin (spectrum)
|
gram+
|
|
bacitracin (spectrum)
|
gram+ (esp staphylococci)
|
|
polymyxin (spectrum)
|
gram- (esp wounds)
|
|
spectinomycin (spectrum)
|
gonococci
|
|
moxalactam (spectrum)
|
broad
|
|
nystatin (spectrum)
|
fungi (esp candida albicans)
|
|
griseofulvin (spectrum)
|
fungi (esp superficial infections)
|
|
amphotericin B (spectrum)
|
fungi (esp systemic infections)
|
|
imidazoles (spectrum)
|
fungi (esp superficial infections)
|
|
sulfonamides (impedes)
|
folic acid metabolism
|
|
isoniazid (impedes)
|
cell wall synthesis
|
|
metronidazole (impedes)
|
cell metabolism
|
|
chloroquine (impedes)
|
cell metabolism
|
|
fluoroquinolones (impedes)
|
dna synthesis
|
|
penicillins (impedes)
|
cell wall synthesis
|
|
cephalosporins (impedes)
|
cell wall synthesis
|
|
aminoglycosides (impedes)
|
protein synthesis
|
|
chloramphenicol (impedes)
|
protein synthesis
|
|
tetracyclines (impedes)
|
protein synthesis
|
|
macrolides (impedes)
|
protein synthesis
|
|
vancomycin (impedes)
|
cell wall synthesis
|
|
rifampin (impedes)
|
rna synthesis
|
|
clindamycin (impedes)
|
protein synthesis
|
|
bacitracin (impedes)
|
cell wall synthesis
|
|
polymyxin (impedes)
|
cell membrane function
|
|
spectinomycin (impedes)
|
protein synthesis
|
|
moxalactam (impedes)
|
protein synthesis(?)
|
|
nystatin (impedes)
|
cell membrane function
|
|
griseofulvin (impedes)
|
nucleic acid synthesis
|
|
amphotericin B (impedes)
|
cell membrane function
|
|
imidazoles (impedes)
|
inhibit sterol synthesis
|
|
sulfonamides (effect)
|
kidney and liver damage, allergic reactions
|
|
isoniazid (effect)
|
liver damage
|
|
metronidazole (effect)
|
tumors in mice
|
|
chloroquine (effect)
|
eye damage
|
|
fluoroquinolones (effect)
|
few reported
|
|
penicillins (effect)
|
allergic reactions, selection of penicillinase producing strains
|
|
cephalosporins (effect)
|
occasional allergic reactions
|
|
aminoglycosides (effect)
|
hearing defects, kidney damage
|
|
chloramphenicol (effect)
|
aplastic anemia, gray syndrome
|
|
tetracyclines (effect)
|
destruction of natural flora, discoloration of teeth, stunted bones
|
|
macrolides (effect)
|
gastrointestinal distress
|
|
vancomycin (effect)
|
ear, kidney damage
|
|
rifampin (effect)
|
liver damage
|
|
clindamycin (effect)
|
pseudomembranous colitis
|
|
bacitracin (effect)
|
kidney damage
|
|
polymyxin (effect)
|
kidney damage
|
|
spectinomycin (effect)
|
few reported
|
|
moxalactam (effect)
|
few reported
|
|
nystatin (effect)
|
few reported
|
|
griseofulvin (effect)
|
occasional allergic reactions
|
|
amphotericin B (effect)
|
fever, gastrointestinal destress
|
|
imidazoles (effect)
|
few reported
|