Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
12 Cards in this Set
- Front
- Back
|
what antibiotic might be affected if the bacteria use another pathway to form DNA precursers
|
Trimethoprim
|
|
|
altered PBPs are linked with resistant to what antibiotics
|
1. methicillin
2. penecillin in Neisseria, H. influenzae, and p. aeruginosa |
|
|
alteration of cell wall precurser targets plays a role in what two antibiotic resitance
|
vancomycin and teichoplanin
|
|
|
alteration of 30s subunit (alteration of ribosomal targets) play a role in what antibiotic resistant
|
streptomycin
not as common in gentamycin because it has multiple ribosomal targets |
|
|
methylation of 23S rRNA (component of 50S ribosome) plays a role in what antibiotic resistance
|
erythromycin
|
|
|
antibiotic efflux from the cell plays a role in what two antibiotic resistance
|
tetracycline and fluconazole resistance
|
|
|
altered inner membrane transporters (alterd membrane permeability) affects
|
aminoglycosides, rare since usually deleterious regarding PMF
|
|
|
altered outer membrane porins decreased expressed (altered membrane permeability) affects what three antibiotics
|
B-lactams, nalidixic acid, and chloramphenicol
|
|
|
hydrolyzes lactone ring
|
erythromycin esterase
|
|
|
acetylation of chloramphenicol
|
chloramphenicol acetyltransferase
|
|
|
modifies drug druing transport across the cytoplasmic membrane
|
aminoglycoside modifying enzymes
|
|
|
cleaves the b-lactam ring
|
B-lactamases -
|
