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11 Cards in this Set
- Front
- Back
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Beta-lactam antibiotics
1. cidal or static? 2. Mechanism of action? 3. Examples? |
1. Bactericidal
2. Inhibition of synthesis of bacterial peptidoglycan cell wall 3. Penicillins Penicillinase resistant penicillins Aminopenicillins Antipseudomonal penicillins Carbapenems Monobactams Cephalosporins |
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Fluoroquinolones
1. cidal or static? 2. Mechanism of action? 3. Examples? |
1. Bactericidal
2. Inhibits bacterial DNA gyrase which causes breakage of DNA and affects DNA replication and transcription halting growth. 3. Ciprofloxacin (Cipro) Gatifloxacin (Zymar) Gemifloxacin (Factiv) Levofloxacin (Levaquin) Moxifloxacin (Avelox, Vigamox) Norfloxacin (Noroxin) Ofloxacin (Floxin, Ocuflox) |
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Aminoglycosides
1. cidal or static? 2. Mechanism of action? 3. Examples? |
1. Bactericidal
2. Cause misreading of mRNA 3. Amikacin (Amikin) Gentamicin (Gentak) Kanamycin (Kantrex) Neomycin Streptomycin Tobramycin (AKTob, Tobrex) |
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Macrolides
1. cidal or static? 2. Mechanism of action? 3. Examples? |
1. Usually static; cidal in high concentrations against very susceptible organisms
2. Inhibit protein synthesis 3. Azithromycin (Zithromax) Clarithromycin (Biaxin) Dirithromycin (Dynabac) Erythromycin (Eryc, Erytab, EryPed, EES, Erythrocin) |
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Ketolides
1. cidal or static? 2. Mechanism of action? 3. Examples? |
1. Bacteriostatic
2. Inhibit protein synthesis 3. Telithromycin (Ketek) |
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Lincosamides
1. cidal or static? 2. Mechanism of action? 3. Examples? |
1. Bacteriostatic, cidal in high concentrations
2. Suppress protein synthesis 3. Clindamycin (Cleocin, Clindamax, Clindesse, Evoclin) |
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Glycopeptides
1. cidal or static? 2. Mechanism of action? 3. Examples? |
1. Bactericidal
2. Inhibit cell wall synthesis 3. Vancomycin (Vancocin) |
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Sulfonamides
1. cidal or static? 2. Mechanism of action? 3. Examples? |
1. Bacteriostatic
2. Affect synthesis of folic acid 3. Sulfadiazine Sulfamethoxazole Sulfisoxazole (Gantrisin) Sulfacetamide (Bleph-10, Carmol, Klaron) |
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Trimethoprim
1. cidal or static? 2. Mechanism of action? 3. Examples? |
1. Bacteriostatic
2. Affect synthesis of folic acid 3. Primsol Proloprim Trimpex |
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Tetracyclines
1. cidal or static? 2. Mechanism of action? 3. Examples? |
1. generally static
2. Inhibit protein synthesis 3. Demeclocycline (Declomycin) Doxicycline (Adoxa, Doryx, Doxy-100, Monodox, Periostat, Vibromycin) Minocycline (Dynacin, Minocin) Tetracycline (Sumycin) |
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Glycylcyclines
1. cidal or static? 2. Mechanism of action? 3. Examples? |
1. Bacteriostatic
2. Inhibit protein synthesis 3. Tigecycline (Tygacyl) |
