Antiarrythmic

Front 1

antiarrythmic acts same mechanism as ?

Back 1

local anestethics

Front 2

Class 1 drugs slows phase

Back 2

rising of phase 0

Front 3

Class 1 causes

Back 3

decreased excitability and contraction

Front 4

Class 1 drugs are

Back 4

use -dependance

Front 5

Class 1a

Back 5

prolongs the ap and slows phase 0

Front 6

Class 1b

Back 6

shortens the refractory period

Front 7

Class 1c

Back 7

slows rise phase 0
slowing of conductance

Front 8

three class 1a drugs

Back 8

Quinidine Procainamide Disopyramide

Front 9

procainamide is adjusten in wich patients

Back 9

renal failure patients

Front 10

Quinidine can induce

Back 10

polymorphic ventricular tachycardia

Front 11

toxic levels of quinidine ?

Back 11

Nausea Vomiting Diarrhea

Front 12

Quinidine treats

Back 12

atrial , AV-junction and ventricular tachycardia

Front 13

Procainamide actions

Back 13

are similar to quinidine

Front 14

Procainamide adverse

Back 14

CNS depression hallucinatory
induces hypotension

Front 15

Disppyramide causes

Back 15

peripheral vasocontriction

Front 16

Disopyramide used in

Back 16

ventricular arrythmias
also has class 3 activity

Front 17

quinidine also has class what activity

Back 17

class 3

Front 18

Quinidine stops

Back 18

Na channels and also K during refractory

Front 19

Class 2 drugs ?

Back 19

Lidocaine
Mexiletine

Front 20

Lidocaine shortens

Back 20

phase 3 of the AP

Front 21

Lidocaine decreases

Back 21

duration of the AP

Front 22

Emergency antiarrythmic agent

Back 22

Lidocaine

Front 23

Lidocaine rapidly

Back 23

associates and dissociates from Na+ channels

Front 24

Lidocaine useful in treating

Back 24

ventricular arrhythmia during myocardial ischemia

Front 25

Lidocaine has little effect on

Back 25

atrial and AV-junction arrythmias

Front 26

Tocainide is a class ?

Back 26

class 1c antiarrythmic

Front 27

what to use in chronic ventricular arrhythmia

Back 27

Mexiletine

Front 28

Tocainide to treat

Back 28

Ventricular tachyarrhythmia

Front 29

Class 1c drugs

Back 29

Flecainide
Propafenone

Front 30

Flecainide approved for ?

Back 30

refractory ventricular arrhytmia
also premature contraction
paroxysmal supraventricular tachycardia

Front 31

action of flecainide

Back 31

suppreses phase 0 upstroke in purkinje and myocardial fibers

Front 32

how is flecainide decreasing automacity

Back 32

by rising the threshold

Front 33

Wich drug has a negative inotropic effect

Back 33

Flecainide

Front 34

Whats slows conduction in all cardiac tissues

Back 34

Propafenone
its a broad spectrum

Front 35

Flecainide atrial or ventricular

Back 35

mostly ventricular

Front 36

which class is b-adrenergic blockers

Back 36

Class 2 antiarrythmics

Front 37

Class 2 drugs diminishes

Back 37

phase 4 depolarisation

Front 38

Class 2 effect is

Back 38

slows heart rate and decreases contractility

Front 39

what is useful in sympathetic induced tachyarrhythmia

Back 39

class 2 anti A

Front 40

most widely used B-blocker in cardiac arrythmias

Back 40

metoprolol

Front 41

Metoprolol reduces risk of

Back 41

bronchospasm

Front 42

Propranolol reduces

Back 42

arrhythmic death after MYI

Front 43

Propranolol prevents

Back 43

ventricular arrhythmia

Front 44

Esmolol is a

Back 44

short acting B-blocker

Front 45

Esmolol used in

Back 45

acute arrhythmias

Front 46

Class 3 drugs acts by

Back 46

blocking potassium channels
prolongs AP, not Phase0

Front 47

Mention four class3 drugs

Back 47

Amiodarone Dronedarone Sotalol
Dofetilide

Front 48

Amiodarone contains

Back 48

iodine

Front 49

Amiodarone dominant effect is

Back 49

prolonged AP

Front 50

Amiodarone also has

Back 50

antianginal effect swell aniarrhthymic

Front 51

Amiodarone to treat

Back 51

severe refractory supraventri
ventricular tachyarrhythmia
atrial fibrillation

Front 52

Most commonly employed antiarrhythmic

Back 52

Amiodarone

Front 53

Amiodarone side effects

Back 53

pulmonary fibrosis
Gi tract and liver toxicity
blueskin due to iodine

Front 54

Dronedarone has less what?

Back 54

tissue accumulation
do not have the iodine

Front 55

Dronedarone side effects

Back 55

Gastrointestinal nausea vomiting
diarrhea

Front 56

Which is most effective and most safest Amiodarone Dronedarone

Back 56

Amiodarone more effectine Dronedarone is more safe

Front 57

Sotalol has a

Back 57

non selective B-blocker activity

Front 58

I-sotalol use in

Back 58

B-blocker use

Front 59

d-sotalol use in

Back 59

anti arrhythmic use

Front 60

Sotalol blocks

Back 60

rapid K+ outward current

Front 61

what can be used in patient with persistent atrial fibrillation

Back 61

Dofetilide

Front 62

Dofetilide is for ?

Back 62

atrial fibrillation
is recommended by experts

Front 63

Class 4 anti arrhythmic are

Back 63

calcium channel blockers

Front 64

Class 4 decreases

Back 64

phase 4 spontaneous depol

Front 65

Class 4 slows

Back 65

AV node

Front 66

Class 4 major action on

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vascular smooth muscle and heart

Front 67

which class 4 is more on the heart

Back 67

Verapamil

Front 68

which class 4 drug acts more on vascular smooth muscle

Back 68

nifepidine

Front 69

Class 4 drugs are

Back 69

Verapamil Nifedipine Diltiazem

Front 70

which class 4 are use dependent

Back 70

Verapamil Diltiazem

Front 71

Verapamil and Diltiazem only responds to

Back 71

open depolarized channels

Front 72

Class 4 more on

Back 72

atrial arrhythmias

Front 73

are associated with Torsades ?

Back 73

Quinidine, disopyramide, and procainamide