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8 Cards in this Set
- Front
- Back
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Antiarrhythmics sodium channel blockers CLASS I-A |
Quinidine, Procainamide, Disopyramide increase AP, Increase effective refractory period, Increase QT interval. Slope of phase 0 : Moderado |
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Antiarrhythmics sodium channel blockers CLASS I-B |
Lidocaine, Mexiletine, Tocainide Decrease action potential. Preferentially affect ischemic or depolarized Purkinje and vent, tissue. ventricular aarrhythmias especially post-MI Slope of phase 0 : Leve |
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Antiarrhythmics sodium channel blockers Class I-C |
Flecainide, Propafenone prolongs ERP, Minimal effect on AP duration Proarrhythmic, especially post-MI CONTRAINDICATED Slope of phase 0 : Severe |
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Antiarrhythmics B- blockers Class-II |
Metropolol, propanolol, esmolol, atenolol, timolol, carvedilol Decrease SA and AV nodal Activity by decreased cAMP, Decreased Ca+ currents. suppress abnormal pacemakers by deacreasing slope of phase 4 Treat B-blocker overdose with Saline, Atropine, Glucagon. |
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Antiarrhythmics Potassium channel blockers Class III |
Amiodorone, ibutilide , dofetilide, sotalol increase AP duration, atrial flutter sotalol: torsades de pointes Ibutilide: torsades de pointes Amiodarone: pulmonary fibrosis, gray skin deposits resulting in photodermatitis. |
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Antiarrhythmics calcium channel blockers Class IV |
Verapamil, Diltiazem decrease conduction velocity, increase ERP, increase PR interval slow rise of action potential prolonged repolarization at AV node |
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Adenosine |
increase K+ out of the cells, hyperpolarizing the cell and decrease Ica+. drug of choice in diagnosing/abolishing supraventricular tachycardia |
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Mg2+ |
Effective in torsades de pointes and digoxin toxicity |
