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25 Cards in this Set
- Front
- Back
- 3rd side (hint)
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Class I |
Na+ channels blockers |
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Class Ia |
Procainamide Dysopiramide Quinidine |
Queen Proclaims Diso's pyramid |
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Class IB |
Mexiletine Tocainide Lidocaine Phenytoin |
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Class IC |
Encainide Flecainide Propafenone |
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Class IA MOA |
Increase AP duration Increase ERP Increase QT interval Phase 3 repolarization is delayed Phase 0 depolarization is delayed |
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Class IA Uses |
Re-entry arrhythmia Ectopic SVT VT Wolff-Parkinson-white |
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Class IA S/E |
Quinidine - cinchonism (headache and tinnitus)
Procainamide- SLE-like Syndrome
Disopyramide- HF
Thrombocytopenia Torsades de Pointes due to increase QT interval |
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Class IB Uses |
Post MI Acute ventricular Arrhythmias Digitalis induced Arrhythmias Ventricular tachycardia and ventricular fibrillation |
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Class IB S/E |
Mexiletine- Severe GI upset
Tocainide- Pulmonary fibrosis
Phenytoin - hirsutism, gingival hyperplasia |
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Class IB MOA |
Decrease AP potential Exhibit zero order kinetics Don't affect AP length |
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Class IC MOA |
Prolongs refractory period on AV node |
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Class IC use |
SVT Atrial fibrillation |
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Class IC S/E |
Proarrhythmic, especially post MI (contraindicated) |
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Class II |
Beta blockers Metroprolol Propranolol Esmolol Atenolol Timolol Carvedilol |
AIDS |
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Class II MOA |
Decrease SA and AV nodal activity
Decrease slope of phase 4
Increase PR interval |
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Class II uses |
SVT Atrial fibrillation Atrial flutter |
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Class II S/E |
Impotence Exacerbation of COPD and asthma Bradycardia AV block CHF Sedation Sleep disturbance May mask hypoglycemia
Metropolol - dyslipidemia
Propranolol - exacerbate vasospasm in Prinzmental angina
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Class III |
K+ channel blockers Sotalol Amiodarone Ibutilide Dofetilide |
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Class III MOA |
Increase AP Increase ERP Increase QT interval |
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Class III Uses |
Atrial fibrillation Atrial flutter VT |
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Class III S/E |
Sotalol - torsades de pointes
Ibutilide - torsades de pointes
Amiodarone - pulmonary fibrosis, hepatotoxicity, hypo or hyperthyroidism, corneal deposits, skin deposit (blue/gray) and photodermatitis. |
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Class IV |
Ca+ channels blockers Verapamil Diltiazem |
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Class IV MOA |
Decrease conduction velocity Increase ERP Increase PR interval |
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Class IV uses |
Prevent nodal Arrhythmias |
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Class IV S/E |
Constipation Flushing Edema CHF AV block |
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