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7 Cards in this Set
- Front
- Back
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Nitroglycerin |
Sublingual/ Transdermal/ Topical / Oral /IV/ treat acute angina attacks Skin patch = slow release (prevent angina attacks) Ointment= absorbed several hours (pt with Angina and MI) Oral = sustained release capsules (prevent angina attacks) IV solution (decrease preload/ decrease afterload) |
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Isosorbide Dinitrate |
sublingual/ oral / prevent and treat angina attacks/ same effects like nitroglycerin BUT slower onset and greater duration |
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Dihydropyridines |
potent vasodil=> decrease bp sufficiency / Reflex tachycardia |
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Diltiazem & Verapamil |
Decrease SA node automaticity Decrease Cardiac contractility Decrease AV nodeconstriction velocity Typical angina Variant angina Suppress cardiac contractility pt. typical angina without heart failure-> decrease heart contractility / decrease HR and effects on wall tension avoid combo with verapamil -> Decrease Cardiac output |
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Nimodipine |
Decrease Neurologic Complications- subarrchnoid hemorrhage/ dilates small cerebral vessels/ cerebral ischemia: excess ca2+ release/ admin only in mouth /feeding tube NEVER IV |
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Ranolazine
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1st line Chronic stable angina/ block pathologic / decrease diastolic wall tension/ decrease oxygen consumption and improve diastolic subendocardial perfusion increase exercise capacity decrease need nitroglycerin use use with beta blockers and nitrates improves diabetics |
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Trimetazidine |
Inhibit ketoacyl coenzyme A thiolase Decrease anginal episodes Increases Duration exercise Increases ejection fraction |
