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9 Cards in this Set
- Front
- Back
cetirizine |
Competes with histamine for the normal H1–receptor sites on effector cells of the gastrointestinal tract, blood vessels and respiratory tract. Penetrates CNS less well than chlorpheniramine so less sedating. |
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dexamethasone |
Binds with high affinity to specific cytoplasmic receptors to produce inhibition of leukocyte infiltration at the site of inflammation, interference in the function of mediators of inflammatory response, and suppression of humoral immune responses
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charcoal, activated |
Adsorbs several drugs and toxins, and used in treatment of poisoning with certain agents |
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amoxicillin + clavulanic acid (co–amoxiclav) |
Interferes with synthesis of bacterial cell wall peptidoglycan. After attachment to penicillin–binding proteins on bacteria, inhibits transpeptidation enzyme that cross–links peptide chains attached to backbone of peptidoglycan. Clavulanate competitively and irreversibly inhibits wide variety of beta–lactamases produced by certain bacteria, making drug combination more potent. |
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flucloxacillin |
Interferes with synthesis of bacterial cell wall peptidoglycan. After attachment to penicillin–binding proteins on bacteria, inhibits transpeptidation enzyme that cross–links peptide chains attached to backbone of peptidoglycan. Stable against hydrolysis by variety of beta–lactamases, including penicillinases, and cephalosporinases and extended spectrum beta–lactamases |
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Cefotaxime |
Inhibition of cell wall synthesis via affinity for penicillinbinding proteins (PBPs). Displays resistance to penicillinases and so useful to treat infections resistant to penicillin derivatives |
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nitrofurantoin |
Inhibits bacterial acetyl–coenzyme A, interfering with organism's carbohydrate metabolism. Can also disrupt bacterial cell wall formation |
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oxytetracycline |
Reversibly binds to 30S ribosomal subunit and prevents amino–acyl tRNA from binding to the A site of the ribosome, inhibiting translation and thus cell growth.
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vancomycin |
glycopeptide antibiotic which acts by inhibiting cell wall synthesis |