Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
12 Cards in this Set
- Front
- Back
Phenoxybenzamine
-Class -Therapeutic use -Adverse effects |
-Alpha blocker (a1,a2)- covalent irreversible binding
-pheochromocytoma (inoperable management), sympathetic dystrophy and causalgia -postural hypotension, tachycardia, cardiac arrhythmias, peripheral edema, nasal stuffiness, fatigue, nausea, urinary frequency/incontinence, sexual dysfunction (priapism), skin rashes |
|
Prazosin
-Class -Therapeutic use -Adverse effects |
-Alpha blocker (a1)
-urological problems to improve flow (BPH), overflow incontinence, Raynauds dz, chronic HTN, HTN crisis, heart failure, sympathetic dystrophy and causalgia -urge incontinence, exertional angina, all disorders leading to postural hypotension |
|
Tamsulosin
-Class -Therapeutic use -Adverse effects |
-Alpha blocker (a1)
-helps with BPH (prostate has lots of a1 receptors) so it decreases the contraction |
|
Propanolol
-Class -Therapeutic use -Adverse effects |
-Nonselective B blocker
-local anesthetic action |
|
Pindolol
-Class -Therapeutic use -Adverse effects |
-Nonselective B blocker (partial beta agonist activity)
-local anesthetic action |
|
Timolol
-Class -Therapeutic use -Adverse effects |
-Nonselective B blocker
-profoundly lowers IOP |
|
Sotalol
-Class -Therapeutic use -Adverse effects |
-Nonselective B blocker
-pronounced K channel blocking activity |
|
Atenolol
-Class -Therapeutic use -Adverse effects |
-Selective B blocker (b1)
|
|
Metoprolol
-Class -Therapeutic use -Adverse effects |
-Selective B blocker (b1)
-local anesthetic action |
|
Esmolol
-Class -Therapeutic use -Adverse effects |
-Selective B blocker (b1)
-Parenteral administration ONLY |
|
Labetalol
-Class -Therapeutic use -Adverse effects |
-Alpha-beta blocker (a1 ant, b1,2 partial agonist)
-local anesthetic activity, dec in TPR (causes reflex tachy), |
|
Metyrosine
-Class -Therapeutic use -Adverse effects |
-Indirect acting antiadrenergic (inhibits catecholamine synth)
(inhibits tyrosine hydroxylase in catecholamine synthesis) -pre-op pheochromocytoma pt, adjuvant to alpha adrenergic blocker -postural hypotension, diarrhea, sedation, psychic disturbances |