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52 Cards in this Set
- Front
- Back
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enfuvirtide
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host fusion inhibitor
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zidovudine
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NRTI
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didanosine
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NRTI
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AZT
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NRTI
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abacavir
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NRTI
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ddi
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NRTI
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stavudine
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NRTI
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lamivudine
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NRTI
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zalcitabine
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NRTI
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ddc
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NRTI
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nevaparine
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NNRTI
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delavirdine
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NNRTI
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efavirenz
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NNRTI
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saquinavir
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PI
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lopinavir
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PI
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indinavir
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PI
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ritoniavir
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PI
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nelfinavir
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PI
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amprenavir
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PI
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acyclovir
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NT analog
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cidofovir
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NT analog antiviral
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famciclovir
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nucleoside analog
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ganciclovir
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nucleoside analog
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trifluridine
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nucleoside analog
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vidarabine
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nucleoside analog
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foscarnet
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blocks DNA polymerase, RNA polymerase, HIV RT
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famciclovir
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NT analog
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ganciclovir
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NT analog
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trifluridine
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NT analog (topical)
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vidarabine
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NT analog (topical)
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amantadine
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M2 inhibitor of flu
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rimantadine
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M2 inhibitor of flu
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Zanamivir
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neuramidase inhibitor of flu
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oseltamivir
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neuramidae inhibitor of flu
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emtricitabine
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NRTI
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tenofovi
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NRTI
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which of the NT analogs can only be used topically?
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trifluridine
vidarabine |
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which NT analogs are only for CMV use?
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cidofovir
fomivirsen ganciclovir |
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which NT analogs are only for HSV use?
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famciclovir
penciclovir trifluridine vidarabine |
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which NT analogs can be used for either HSV or CMV
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acyclovir
foscarnet valacyclovir |
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which flu drugs are active only against influenza a?
both a and b? |
amantadine, rimantadine
zanamivir, oseltamivir |
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which NT analog doesn't cause chain termination?
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famciclovir
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which NT analogs are guanosine derivatives
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acyclovir
famciclovir ganciclovir (purine analogs) |
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which NT analogs are cytosine derivatives?
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cidofovir
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what do interferons bind to?
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JAK-STAT --> activation of interferon responsive genes
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gene products of interferons
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protein kinase --> phosphorylaton of eIF-2-alpha --> inhibition of translation
2,5-oligoisoadenylate synthase that degrades terminal NT of tRNA, inhibiting translation phosphodiesterase that degrades terminal NT of tRNA inhibiting translation |
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entecavir
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NT analog (hep)
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adefovir
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NT analog (hep)
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ribavirin
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NT analog (hep)
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which hep drug --> teratogenicity
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ribavirin
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adverse effecs of IFN
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acute flu-like syndrome several hrs after injection
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uses of IFN
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chronic HBV, HCV (combine with ribavirin)
genital warts Kaposi's syndrome some HSV infx |
