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19 Cards in this Set
- Front
- Back
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What are the 4 main subtypes of Schizophrenia?
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Catatonic
Paranoid Disorganized Residual |
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What does the dopamine hypothesis suggest in terms of anti-psychotic drugs?
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Drugs which reduced dopaminergic activity reduced acute symptoms and signs of psychoses
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What are some chemical classifications of antipsychotic drugs?
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Phenothiazine compounds
Thioxanthene compounds Butyrophenones |
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What are the 3 subclasses of Phenothiazene compounds?
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Alipathic
Piperidine Piperazine |
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Piperazine derivative anti-psychotics are more potent than _____________ derivative anti-psychotic agents.
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Piperidine
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Chlorpromazine is the prototype of which anti-psychotic drug class?
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Phenothiazine compounds
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Chlorpromazine acts on multiple receptor types. What are some examples?
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Dopamine - central focus
Alpha adrenergic 5-HT2 Serotnin |
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What are some antipsychotic drug-induced endocrine changes commonly seen in women?
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Amenorrhea
Galactorrhea False positive pregnancy test Increased libido |
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What are some antipsychotic drug-induced endocrine changes commonly seen in men?
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Decreased libido
Gynecomastia |
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What are some adverse reactions induced by anti-psychotic drug therapy?
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Extrapyramidal reactions
Tardive dyskinesia Autonomic effects (ie orthostatic hypotension) |
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What is the most significant adverse side effect of anti-psychotic drug therapy?
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Tardive dyskinesia
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___________ can be used to manage extrapyramidal reactions caused by anti-psychotic drug therapy.
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Antimuscarinic agents
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What is an ocular complication of chlorpromazine treatment?
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Cornea and lens deposits
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Which anti-psychotic drug can lead to retinal deposits resembling retinitis pigmentosa?
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Thioridazine
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What is Malignant Neuroleptic Syndrome?
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A life-threatening syndrome observed in patients sensitive to anti-psychotic extrapyramidal effects.
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What is the primary indication for anti-psychotic drug therapy?
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Schizophrenia
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What is the premier drug for management of Bipolar disorder?
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Lithium
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What are some examples of mood-stabilizing drugs?
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Lithium
Carbamazepine Valproic Acid Clonazepam |
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Which anti-psychotic drug can also be used to treat epilepsy?
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Valproic acid
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