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7 Cards in this Set
- Front
- Back
Classify
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>On dopiminergic sys
-precursor:levodopa -decarbox. inhibs: carbidopa, benserazide -D2 Agonist: bromocriptine -MAO-B inhibs:sele/rasagasoline -COMT inhibs: tol/entacapone -glutamate antags:amantadine >On cholinergic sys -central anticholins:benzhexol, benztropine -antiHistamines: diphenyramine, promethazine |
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l-dopa side Fx
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short term:
-hypotension -tachycardia -nausea, vomiting, diarrhoea -angina -bad taste of mouth long term: -on off phenomenon -psychotic symptoms -dyskinesia |
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Benefits of carbidopa
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dose reduction to 1/4th
higher bioavailability no side effects except those due to high DA levels |
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Criteria for orlistat |
BMI 28 with HTN or DM BMI >30 |
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Bariatric surgery options |
Gastric banding Gastric bypass Sleeve gastrectomy |
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When do you stop Carbimazole? |
After 18 months... Speak to seniors |
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Herbal - drug interactions |
Garlic + Aspirin Warfarin + St. John's wort |