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12 Cards in this Set
- Front
- Back
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cisplatin (Platinol) MOA=
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alkylating agent, interferes w/DNA and cell division
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cisplatin (Platinol) indications:
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testicular, ovarian, bladder, lung and colon, and esophageal cancer <solid tumor type>
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cisplatin (Platinol) AE=
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PERIPHERAL NEUROPATHY, nausea/vomiting
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Gemzar (gemcitabine) MOA=
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inhibits DNA synthesis
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Gemzar (gemcitabine) indications =
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adrenocarinoma of PANCREAS, first-line combo for: non-small cell lung cancer, metastatic breast and advanced ovarian cancer
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Gemzar (gemcitabine) AE=
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myelosupression, flu-like syndrome, edema, nausea/vomiting
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Adriamycin/doxorubicin MOA=
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anti-tumor antibiotic, causes damage to cellular DNA, inhibits cell division
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Adriamycin/doxorubicin Indications:
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Hodgkin’s disease, non-hodgkin’s lymphoma; thyroid, lung and stomach cancer; childhood sarcoma
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Adriamycin/doxorubicin AE=
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CARDIAC TOXICITY, VESICANT, urine may be Red, nausea/vomiting, myelosupression, alopecia
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rituximab (Rituxan) MOA=
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monoclonal antibody; lysis of B cells, B cell lymphoma line and decreasing production of Rhumatoid Factor
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rituximab (Rituxan) Indications:
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RHUMATOID ARTHRITIS,chronic lympocytic leukemia, non-hodgkin's lymphoma
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rituximab (Rituxan) AE=
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hypersensitivity rxns, mucocutaneous rxns, lymphopenia
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