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14 Cards in this Set
- Front
- Back
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Atropin
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Tertiary amine / Anti-muscarinic
Crosses BBB Used to reverse Anti-muscarinic poisoning Long lasting myadrisis (pupil dilation) Together with diphenoxylate acts as an antidiarrheal |
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Scopolamine
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Tertiary amine
It crosses BBB Helps control seasickness Small amount has small sedating effect Large amount it causes mild euphoria |
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Tropicamide
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Anti-muscarinic
Short acting myadriatic agent Tertiary (crosses BBB) May rise intraocular pressure |
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Tolterodine
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Anti-muscarinic
Drug of choice to manage an overactive bladder with symptoms of increased urgency or frequency |
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Oxybutynin
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3 amine Anti muscarinic
Together with Tolterodine help control an overactive bladder with increased urgency or frequency May increase tone in bladder muscle Helps close sphincter |
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Ipratropium
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Quaternary amine - anti-muscarinic
Used to treat COPD Not effective for asthma |
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Propantheline
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Quaternary amine - anti-muscarinic
Orally administered / very low cardiovascular activity, short duration 6 h Competitive mAChR antagonist non-obstructive irritable bowel syndrome, other GI disturbances Causes excessive sweating |
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Nicotine
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Non depolarizing ganglionic blocker
Used for smoking cessation Stimulation of adrenal medulla, releases NE from chromaffin cells |
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Hexamethonium
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Non-depolarizing ganglionic blocker
The first anti-hypersensitive drug Used in research Poor absorption Autonomic side effects |
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Tetraethylammonium
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Non-depolarizing competitive autonomic ganglia nAChR antagonist
Ganglionic blocker Research Only Poor absorption autonomic side effects |
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Methacholine
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Muscarinic agonist
Ch3 - ACh Used to diagnose bronchial hypersensitivity and asthmatic conditions At high doses can lead to cardiac arrest Choline ester |
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Carbachol
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Muscarinic agonist
ACh - NH2 Last line drug for wide-angle glaucoma Has significant nicotinic activity at Nicotinic receptors |
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Bethanechol
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Direct muscarinic agonist
ACh - NH2 - CH3 Used for post-partum / post-operatively to enhance normal function of GI tract and bladder; promotes intestinal motility and tone Xerostomia Little effect on CV system |
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Pilocarpine
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Miotic agent for wide angle glaucoma (contracts the ciliary muscle and opens the canal of schlemm)
Cholinergic agonist |
