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27 Cards in this Set
- Front
- Back
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Metoprolol Uses
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Stable angina prophylaxis
ACS |
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Metoprolol Effects
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Dec O2 demand
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Metoprolol contraindications
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Unstable hemodynamics
AV node block |
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Nitroglycerin Effects
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Smooth muscle relaxation
Dec preload Dec vasospasms |
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Nitroglycerin MOA
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Prodrug Activated by ALDH
Inc cGMP Dec MLC phosphorylation |
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Nitroglycerin Elimination
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Hepatic Nitrate Reductase
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Nitroglycerin A/E
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Headache
Hypotension Tachycardia |
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Isosorbide dinitrite Efffects & Differences
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Dec O2 demand
Bioavailable Longer half life PO |
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Diltiazem Drug Type
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Calcium Channel Blocker
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Diltiazem Effects
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Dec Inotropy
Inhibit SA & AV conduction Vasodilation Direct Cardiac Inh Inc Sympathetic tone |
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Diltiazem Uses
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Angina
HTN Arrhythmias Raynaud's |
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Diltiazem Metabolism
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Hepatic
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Diltiazem A/E
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Bradycardia
AV Block Dec CO Hyptoension Constipation |
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Verapamil Drug Type
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Ca channel blocker
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Verapamil Uses
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Angina
HTN Arrhythmias |
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Verapamil A/E
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Bradycardia
AV Block Dec CO Hyptoension CONSTIPATION |
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Amlodipine Drug Type
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Ca channel blocker
dihydropyridine |
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Amlodipine Effects/Uses
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Vasodilation
Angina HTN Raynaud's |
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Amlodipine PK
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Half life 39 hours
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Amlodipine A/E
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Gingival overgrowth
Hypotension Peripheral edema Headache Reflex tachycardia |
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Nifedipine Drug Type
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Ca channel blocker
Dihydropyridine |
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Nifedipine PK
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Half life 2 hours
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Nifedipine A/E
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Gingival overgrowth
Hypotension Peripheral edema Headache Profound reflex tachycardia avoided by extended release |
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Ranolazine MOA
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Prevents extra Na+ channel openings
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Ranolazine Uses
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Resistant Angina
Resistant ACS ALWAYS with dihydropyridine, beta blocker, or nitrate |
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Ranolazien A/E
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Dizziness
Syncope Constipation Prolonged QT (Ventricular arrhythmia) Never with Verapamil or Diltiazem |
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Ranolazine Metabolism
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CYP3A
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