Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
13 Cards in this Set
- Front
- Back
|
NSAID which also inhibits platelet aggregation |
Aspirin |
|
|
Target for most potent NSAIDs (prostaglandin H-synthases) |
PGHS2 -> inducible during inflammation |
|
|
Steroidal anti-inflammatory drugs effects |
Decreased vasodilation and fluid exudation |
|
|
How do glucocorticoids effect inflammation |
By direct transcriptional effects on inflammatory mediators |
|
|
Glucocorticoids drecrease the synthesis of... |
Prostanoids |
|
|
Main glucocorticoid drugs |
Prednisolone, dexamethasone, beclomethasone |
|
|
Earliest H1 histamine antagonist |
Mepyramine |
|
|
Non-sedating H1 antagonist. Does not cross the BBB; undergoes metabolism by CYP3A4. |
Terfenadine |
|
|
Active metabolite of terfenadine |
Fexofenadine |
|
|
H2 receptor anatagonists |
Ranitidine and cimetidine |
|
|
H2 antagonist which inhibits cytochrome P450 and can bind to androgen receptors |
Cimetidine |
|
|
Proton pump inhibitor, shown to be clinically superior to H2 antagonists |
Omeprazole |
|
|
Class of drugs which inhibit gastric acid secretion, other than H2 antagonists and proton pump inhibitors. |
Muscarinic ACh receptor antagonists |
