Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
42 Cards in this Set
- Front
- Back
|
Primaquine
|
Malaria profylaxis
5. Used for extraerythrocytic forms Plasmodium vivax or P. ovale |
|
|
Ciporfloxacin
|
Quinolone derivative
|
|
|
Sulfonamides
|
PABA structural analogs
8. Inhibit Folic acid synthesis |
|
|
Tertacyclines, anuria & the
exception |
Should not be used in anuric pt due to production of (-) Nitrogen balance & ↑d BUN levels.
10. Doxycycline is the exception |
|
|
Ceftriazone
|
3rd generation cephalosporin
12. DOC for bacterial meningitis in kids (ie… HiB) 13. One dose txt of gonorrhea |
|
|
Hepatic coma DOC
|
Neomycin (aminoglycoside) – it supresses the normal flora = ↓g NH4 production = ↓g free
nitrogen levels in the bloodstream. |
|
|
Clavulanic acid
|
Irreversible (-)r of β lactamases, but ot of transpeptidase = use w/ a β lactamase sensitive
penicillin |
|
|
Piperacillin
|
Txt Pseudomonas aeruginosa & Klebsiella
17. Broad spectrum antibiotic |
|
|
Streptomycin (aminoglycoside)
|
Txt Mycobacterium tuberculosis
|
|
|
Isoniazid
|
Most commonly used drug for TB.
20. Usually combined w/ Rifampin and/or Ethambutol 21. Pre Txt w/ Pyridoxine (Vit B6) can prevent peripheral neuritis‘ |
|
|
Pyrantel Pamoate
|
Txt of Hookworm disease
23. Depolarizing NMJ (-)r |
|
|
Buy “AT” 30, “CELL” at 50
|
A = Aminoglycosides
25. T = Tetracyclines 26. C = Chloramphenicol 27. E = Erythromycin (macrolide) 28. L = Clindamycin 29. L = Lincomycin |
|
|
Cefoxitin
|
Txt intraabdominal infections (ie… w/ Bacteroides fragilis)
31. Traditional txt has been Clindamycin & Gentamycin |
|
|
Chloramphenicol
|
Broad spectrum antibiotic
33. Bone marrow depression (common) – Aplastic anemia (rare) 34. Gray baby syndrome (chloramphenicol cannot be conjugated) 35. DOC Typhoid Fever (symptomatic Salmonella infection) 36. DOC HiB meningitis in kids – especially resistant strain to ampicillin |
|
|
Nifurtimox
|
Txt trypanosomiasis
|
|
|
Metronidazole
|
Txt Leishmaniasis & Amebiasis
39. Good for anaerobic bacteria = Bacteroides fragilis 40. DOC Trichomoniasis 41. DOC Giardia lamblia |
|
|
Txt P. carinii
|
TMP-SMX & Pentamidine
|
|
|
Tetracycline
|
Txt of Brucellosis & Cholera
44. Txt Rocky Mountain Spotted Fever 45. Txt spirochete infections = Lyme disease (Borrelia burgdorferi) |
|
|
TMP-SMX
|
(-) dihydrofolate reductase activity
|
|
|
Benzathine Penicillin G
|
Long duration of action = given once every 3-4 weeks for Txt of Syphilis
|
|
|
Praziquantel
|
Txt Schistosomiasis (trematode [fluke] infections)
|
|
|
Melarsoprol
|
Txt Trypanosomiasis that has neurological symptoms
|
|
|
Stibogluconate
|
Txt Leishmaniasis
|
|
|
Fluconazole
|
Txt fungal encephalitis
|
|
|
Amphotericin B
|
Polyene antifingal
|
|
|
Ketoconazole MOA
|
(-) fungal ergosterol synthesis = disrupts membrane
|
|
|
Griseofulvin MOA
|
Accumulates in keratinized layers of the skin = used in dermatomycoses infections
|
|
|
Mefloquine
|
Anti malarial
56. Txt Chloroquine resistant strains = P. falciparum |
|
|
Chloroquine
|
Txt for Malaria when inside RBC
|
|
|
Nifurtimox
|
DOC Chagas disease due to Trypanosoma cruzi
|
|
|
Erythromycin
|
Used in pts allergic to penicillins
|
|
|
Nystatin
|
Topical txt of superficial mycotic infections = Candidiasis
|
|
|
Acyclovir
|
Guanine analog
62. Txt Herpes infections |
|
|
Imipenem
|
Used w/ Cilastatin
64. Can cause seizures |
|
|
Cefoperazone side effects
|
Bleeding due to vit K level alterations
66. Contraindicated in pts w/ bleeding disorders |
|
|
Vancomycin
|
Used for MRSS (methicillin resistant Staph. Aureus)
68. “Red neck”: due to histamine release causes facial flushing |
|
|
Meropenem
|
used w/ Cilastatin
70. Does not cause seizures (cf w/ Imipenem) |
|
|
Nafcillin
|
Only penicillin that does not need dose adjustment in renal impairment
|
|
|
Peripheral neuropathy
|
Seen w/ use of:
73. Metronidazole – Isoniazid – Vincristine – ddI – AZT – Allopurinol |
|
|
Sulfonamides & newborns
|
Kernicterus can occur
|
|
|
“O.N.E.” for gonorrhea
|
Fluoroquinolones used in a one dose deal for gonorrhea:
76. O = Ofloxacin 77. N = Norfloxacin 78. E = Enoxacin |
|
|
Ribavirin
|
Txt RSV (Respiratory Syncytial Virus)
|
