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6 Cards in this Set
- Front
- Back
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What is the mechanism of action of fenofibrate and gemfibrozil?
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Increases fatty acid oxidation in liver and muscles, which decreases productio of tryglycerides in liver.
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Where are fibric acid derivatives metablolized?
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liver
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What are some of the side effects of lovastatin?
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GI effects, mypoathy, rhabodomyolisis, hepatoxicity
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How does ezetimibe work? Where is it metabolized?
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inhibits transfer of cholesterol from intestinal lumen to intestinal cells.
secreted in bile and reabsorbed |
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List some anti-hyperlipidemics
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Niacin
HMG-CoA Reductase inhibitors Intestinal Cholesterol Abosrption Inhibitors Bile Acid Sequestrants Fibric Acid Derivatives |
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Tell me about cholestryramine and colestipol?
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Acts locally in GI tract; binds to bile acids, preventing them from being absorbed; binds to meds
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