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6 Cards in this Set

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What is the mechanism of action of fenofibrate and gemfibrozil?
Increases fatty acid oxidation in liver and muscles, which decreases productio of tryglycerides in liver.
Where are fibric acid derivatives metablolized?
liver
What are some of the side effects of lovastatin?
GI effects, mypoathy, rhabodomyolisis, hepatoxicity
How does ezetimibe work? Where is it metabolized?
inhibits transfer of cholesterol from intestinal lumen to intestinal cells.
secreted in bile and reabsorbed
List some anti-hyperlipidemics
Niacin
HMG-CoA Reductase inhibitors
Intestinal Cholesterol Abosrption Inhibitors
Bile Acid Sequestrants
Fibric Acid Derivatives
Tell me about cholestryramine and colestipol?
Acts locally in GI tract; binds to bile acids, preventing them from being absorbed; binds to meds