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11 Cards in this Set

  • Front
  • Back
amphotericin B
broad spectrum
lifethreatening infections aspergillus meningitis
iv liposome suspension
Cytolytic pore forming via erosterol binding
renal impairment!
decreased[K]
Nystatin
cytolytic ergosterol
topical for candida
Flucytosine
Bone marrow toxicity
inhibits RNA DNA synth
combo for menigitis and blastomycoses
Griseofulvin
interaction with warfarin
fungistatic micritubule inhibition
PO for dermatophytes
Ketaconazole
affects steroid synth and p450
PO mucous candida

blocks ergosterol synth
Miconazole/Clotrimazole
topical candida dermatophytes OTC
Blocks ergosterol synth
Intracinazole
block of ergosterol
po no csf penetration
potent for systemic infections of aspergillus dermatophytoses
Fluconazole
CSF penetration
cryptococcal meningitis
blocks ergosterol
Verconazole
blocks ergosterol
csf penetration
meningitis andpergillus and candida
Terbinafine
Naftifine
cutaneous mycoses not candida
nail infections
inhibits squalene matebolism
Caspofungin
invasive candidiasis
blocks cell wall synth
candida and aspergillus