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11 Cards in this Set
- Front
- Back
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amphotericin B
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broad spectrum
lifethreatening infections aspergillus meningitis iv liposome suspension Cytolytic pore forming via erosterol binding renal impairment! decreased[K] |
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Nystatin
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cytolytic ergosterol
topical for candida |
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Flucytosine
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Bone marrow toxicity
inhibits RNA DNA synth combo for menigitis and blastomycoses |
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Griseofulvin
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interaction with warfarin
fungistatic micritubule inhibition PO for dermatophytes |
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Ketaconazole
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affects steroid synth and p450
PO mucous candida blocks ergosterol synth |
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Miconazole/Clotrimazole
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topical candida dermatophytes OTC
Blocks ergosterol synth |
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Intracinazole
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block of ergosterol
po no csf penetration potent for systemic infections of aspergillus dermatophytoses |
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Fluconazole
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CSF penetration
cryptococcal meningitis blocks ergosterol |
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Verconazole
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blocks ergosterol
csf penetration meningitis andpergillus and candida |
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Terbinafine
Naftifine |
cutaneous mycoses not candida
nail infections inhibits squalene matebolism |
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Caspofungin
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invasive candidiasis
blocks cell wall synth candida and aspergillus |
