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25 Cards in this Set

  • Front
  • Back
Phenelzine
Monoamine Oxidase (MAO) inhibitor.

Treatment for Depression.
Isocarboxizid
Monoamine Oxidase Inhibitor.
Treatment for depression.
Tranylcypromine
Monoamine Oxidase Inhibitor.

Treatment for depression.
Moclobemide
Monoamine Oxidase Inhibitor.

Treatment for depression.
Deprenyl
Monoamine Oxidase Inhibitor.

Treatment for depression.
Adverse Effects of Monoamine Oxidase Inhibitors
CNS Effects: dizziness, headache, blurred vision, peripheral edema.

Diet Restrictions: No foods with Tyramine due to increased risk of hypertensive crisis. (Can't break down Tyramine.)
Amitryptiline
Tricyclic Anti-depressant.
I-DAN.
Adverse Effects of Serotonin Selective Re-uptake Inhibitors
(Generally CNS) Nausea, Nervousness, Insomnia, Sexual Dysfunction, Headache, Serotonin Syndrome & increased SUICIDE

Citalopram, Paroxetine, Fluroxitine, Sertaline. (think teens are sad)
(Crying People Feel Sad)
Adverse Effects of Tricyclic Anti-Depressants
Orthostatic Hypotension, Dizziness, Reflex Tachycardia (Alpha 1 receptors)

Inhibition of H1 Receptor (Histamine): weight gain, sedation

Inhibtion of Cholinergic Receptors: memory dysfunction, blurred vision, dry mouth, sinus tachycardia, Urine retention, Constipation
Sertraline
Selective Serotonin Re-uptake Inhibitor (SSRI)

Treatment for Depression

(Crying People Feel Sad)
Reserpine
Used in Monomaine Hypothesis. In test animals, it lowered the amount of monoamines (NE) and caused depression.

Reversal of depression with added monoamines.
Tianeptine
Accelerates Serotonin (5HT) reuptake.

Anit-depressant and Anxiolytic.
Monoamine Oxidase Inhibitors
Inhibit enzymes that degrade NE, DA, and 5HT.

Anti-depressant.

Ex) Phenelzine, Deprenzyl
Desimipramine
Tricyclic Anti-Depressant.

(IDAN)
Mechanism of Action of Re-Uptake Inhibitors
Increase MAO levels.

Block presynaptic transport proteins and enhance the Pre & Post-synaptic activity.

Ex) Imipramine, Fluoxetine.

Anti-Depressant
Imipramine
Tricyclic Anti-Depressant.

(IDAN)
Citalopram
Serotonin Selective Re-uptake Inhibitor (SSRI).

Anti-depressant

(Crying People Are Sad)
Nortryptiline
Tricyclic Antidepressant

(I-DAN)
Sertraline
Selective Serotonin Re-uptake Inhibitor (SSRI)

Anit-Depressant

Crying People Are Sad
Venlafaxine
Both a SSRI and a mixed action inhibitor of NE and DA.
Fluroxetine
Selective-Serotonin Re-uptake Inhibitor (SSRI)

Anti-Depressant.

(Crying People Feel Sad)
Paroxetine
Selective Serotonin Re-uptake Inhibitor (SSRI)

Anti-Depressant.

(Crying People Feel Sad)
Amoxapine
Mixed action reuptake inhibitor.

Anti-depressant

(BAT)
Buspropion
Mixed action reuptake inhibitor.

Anti-depressant

(BAT)
Trazodone
Mixed action reuptake inhibitor.

Anti-depressant

(BAT)