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6 Cards in this Set
- Front
- Back
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MOA for Quinolones (fluoroquinolones)
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- bactericidal
- inhibits DNA enzymes (topoisomerase,,, gyrase) that are needed for DNA replication |
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indications for Quinolones (fluoroquinolones)
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- Very broad spectrum of activity
- gram pos - gram neg - LIMITED/poor anerobic coverage - activity against enterococci - activity against P. aeruginosa (ciprofloxacin) |
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Name some (Fluoro)Quinolones
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ciprofloxacin
levofloxacin ofloxacin gemifloxacin moxifloxacin norfloxacin |
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which (Fluoro)Quinolone is only used for UTI?
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norfloxacin
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which (fluoro)Quinolone has no activity against psedomodas?
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levofloxacin
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What are the common AE of (fluoro)quinolones?
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- Arthropathy --affects connective tissue --not used in children
- GI & hypersensitivity rxns |
