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20 Cards in this Set
- Front
- Back
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Lidocaine Drug Type and Uses
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IB
Post MI Vtach suppression Frequency dependent AP inhibition Stop DADs |
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Lidocaine A/E
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Neurotoxicity
Proarrhythmia --> monomorph Vtach Activate dormant in structural damage |
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Flecainide Type and Uses
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IC
Afib (termination & prophylaxis) |
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Flecainide A/E
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Proarrhythmia esp in structure damaged
Dec Ino Widening QRS |
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Procainamide Drug Type and Uses
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IA
Life-threatening Vtach Inhibit reentry K+ prolongs AP & refractory period |
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Procainamide Metabolism
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Renal and Hepatic Elim
N-acetyl pro active metabolite |
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Procainamide A/E
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Proarrhythmia
Monomorphic (EADs) Torsade (IKr) Dec ino Bone marrow suppression Lupus QT prolongation QRS prolongation |
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Sotalol Drug Type and Uses
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III
d-sotalol is a beta blocker Afib Vtach esp with implanted devices Ischemic heart disease |
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Sotalol A/E
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Proarrhythmia: torsade
Dec Ino (beta blocker) Bronchoconstriction |
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Amiodarone Drug Type and Uses
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III
IV & PO (immediate - long term) Vtach Afib Prevents cardiac arrest |
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Amiodarone MOA
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IKr & IKs inhibition
Na block Ca block Non-comp block of alpha & beta receptors |
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Amiodarone A/E
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Pulm tox
Hepatotox Skin deposits Neuropathy Thyrotox Hypothyroidism (T4 --X--> T3) Increase Digoxin & Warfarin |
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Amiodarone PK
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LONG Half life (weeks)
Huge loading dose |
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Propranolol Drug Type and Uses
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II
Afib Slow AP at AV node Vtach |
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Propranolol Effects
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Dec ino
Dec Ca Dec DADs |
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Verapamil Drug Type and Efects
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IV
Slows AV conduction |
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Adenosine MOA
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Hyperpolarizes & blocks AV node (K+)
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Adenosine Uses
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No reentry
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Adenosine PK
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Half life seconds
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Adenosine A/E
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Cardiac arrest
Chest pressure Flushing Bronchoconstriction (A3) Theophylline (receptor antagonist) Dipyridamole (inh ando reuptake, prolonging effect) |
