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5 Cards in this Set
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- Back
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Benzodiazepines similarly as barbiturates. ( binding to GABA) but also increase the number if chloride channels.
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Tranquilizers - chlordiazepoxide (Librium) diazepam (Valium ) alprazolam (Xanax ) lorazepam ( Ativan)
Hypnotics to overcome insomnia - flurazepam, triazolam. Anti convulsants - diazepam & clonazepam. Pre op sedative for children - midazolam ( versed) |
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Barbiturates - act by binding to GABA receptors and enhances the transmission of chloride ions. Thereby inhibiting the depolarization of neurons.
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Ultra short acting - thiopental, methohexital.- for induction of gen anesthesia.
Short acting - pentobarbital, secobarbital - treating insomnia. Intermediate acting - amobarbital, butabarbital - treating insomnia. Long acting - phenobarbital, mephobarbital, primidone - treating certain type of seizures. |
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Flumazenil
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Benzodiazepine antagonist, used to reverse the residual effects of benzodiazepine in the event of an overdose.
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Anti insomnia agents (GABA-BZ agonists)
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Zolpidem (ambien), eszopiclone (lunesta), zaleplon (sonata)
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Buspirone (Bu Spar)
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Anti anxiety agent. (no anti convulsant, or skeletal muscle relaxant properties)
Partial agonist at serotonin receptor. |
