Anterior Lobe Of Pituitary Pharms

Front 1

pituitary gland secr hormones that reg endocrine act of?

Back 1

thyroid gland
adrenal cortex
repro organs
melanin production stimulates

Front 2

neuroendocrine system controlled by? and they coordinate?

Back 2

hypothalamus
pituitary

body fnx's by transmitting messages between cells and tissues

Front 3

endocrine syst contrast nervous syst by?

Back 3

electric impulse and neurotransmitter communication
neurons to neurons or tissues or organs or glands

Front 4

endocrine hormone pw?

Back 4

hormones = blood= targets site= target cells

Front 5

nerve impulse response time?

Back 5

milliseconds

Front 6

endocrine hormones response time?

Back 6

seconds
days weeks
months

Front 7

interrelation between nervous syst and endocrine?

Back 7

hormone release can b contr by nerve impulses

hormones can also stim or inh release of nerve impulses

Front 8

pituitary hormones comtrol?

Back 8

almost all other endocrine glands of body

Front 9

pituitary hormones promote?

Back 9

growth and control of water balance in bod

Front 10

descr and situate pituitary gland?

Back 10

small
bean shaped
reddish grey organ

located saddle shaped depression= sella turcica
floor of skull= sphenoid bone
attatched tp base of brain= stalk
near hypothalamus

Front 11

two pituitary lobes?

Back 11

anterior = adenohypophysis

posterior = neurohypophysis

Front 12

adenohypophysis?

Back 12

epithel cells groups seperated= blood channels

Front 13

neurohypophysis?

Back 13

nervous ct and nerve like secxr cells

Front 14

intermediate lobe?

Back 14

area betw ant and post lobe

Front 15

ant pit gland hormones control functions how many? what are they? composed of?

Back 15

10- 12 functions in body

peptides

amino acids

Front 16

6 hormones released from ant pit ?

Back 16

GH
TSH
PROLACTIN
ACTH adrenocorticotropic hormone
FSH
LH

Front 17

GH?

Back 17

normal skeletal growth
neutralized by gonadal sex hormones during adolescence

Front 18

TSH?

Back 18

controls
normal fnxing
thyroid gland

Front 19

ACTH?

Back 19

activity of cotex of adrenal glands
and stress reaction

Front 20

PROLACTIN?

Back 20

initiates milk secrx
mammary glands during pregnancy

Front 21

FSH?

Back 21

stim form = graafian follicle
in female ovary

and spermatozoa dev in male

Front 22

LH?

Back 22

stim form of ovarian hormones
after ovulation
initiates lactation

male:
stim testes in tissue to elaborate testosterone

Front 23

hormonal act of ant pituitary contr by?

Back 23

hypothalamic chemical messangers

Hint 23

slide

Front 24

hypothalamic releasing hormones?

Back 24

TRH = THYROTROPIN RELEASING HORM
CRH= CORTICOTROPIC RELEASING HORMONE
GHRH= GROWTH HORMONE RELEASING HORMONE
GnRH = GONADOTROPIN RELEASING HORMONE
PRH= PROLACTIN RELEASING HORMONE
PIH= PROLACTIN INHIBITING HORMONE

Front 25

hypothalamic hormones 》 ant pituitary》 targets

Back 25

targets

Front 26

adrenocorticotropic related drugs?

Back 26

cosyntropin ( synthetoc human ACTH ADRENOCORTICOTROPIN HORMONE)

Front 27

cosyntropin ?

Back 27

for diax of adrenal insufficiency
ACTH is used in tx of?
multiple sclerosis
infantile spasms= west syndrome between 3 and 12 mnths

Front 28

A/E ACTH ?

Back 28

osteoporosis
hpt
peripheral oedema
hypokalemia
emotional disturbances
incr risk of infections

Front 29

GH RELATED DRUGS ARE AND DO?

Back 29

somatotropin
by ant pituitary
in response to GHRH
pulsatile manner
highest levels during sleep

Front 30

somatotropin stimulates?

Back 30

cell prolif
bone growth

Front 31

synthetic somatotropin produced during?

Back 31

recombinant DNA tech

Front 32

animal somatotropin?

Back 32

ineff in humans

Front 33

GH , somatotropin indicated for?

Back 33

growth fx in children, GH def
growth failure d/t PRADER WILLI SYNDROME = (GENETIC DISORX RESULTS IN POOR MUSCLE TONE AND LOW LEVELS SEX HORMONES)

management of AIDS wasting syndrome

short bowel syndrome = cannot absorp enough fluids and nutrients

replacemnt in adults with confirmed GH deficiency

Front 34

somatotropin not indicated for?

Back 34

pediatrics with closed epiphysis

increased intracranial pressure

diabetic retinopathy

obese patients with PRADER WILLI SYNDROME

Front 35

GHIH RELATED DRUGS= SOMATOSTATIN = found in? and inhibits release of?

Back 35

neurons
intestine
pancreas

GH
INSULIN
GLUCAGON
GASTRIN

Front 36

analog to somatostatin?

Back 36

octreotide

Front 37

octreotide used to?

Back 37

acromegaly

Front 38

octreotide A/E?

Back 38

diarrhea
abdominal pain
flatulence
nausea
steatorrhea
delay of gallbladder emptying
long term tx = asympromatic cholesterol gallstones

Front 39

GRH DRUGS gonadotropin releasing hormone related drugs

Back 39

gonadorelin

Front 40

gonadorelin explain?

Back 40

subjected to pulsatile secrections
essential to FSH AND LH SECRETION FROM PITUITARY

Front 41

synthetic analogs of GnRH? effective in?
therefore tx of?

Back 41

leuprolide

goserelin

nafarelin

histrelin

they are agonists

supressing prodx of gonadal hormones when admoinistered continuously

prostatic cancer
endomertriosis
precoscious puberty

Front 42

synthetic analogs of GnRH related drugs A/E? in women

Back 42

hot flushes
precoscious puberty
diminished puberty
diminished libido
depression
ovarian cysts

Hint 42

precocious = mature in development

Front 43

AE IN MEN synthetic analogs of GnRH RELATED DRUGS?

Back 43

bone pain
edema
gynecomastia
hot flushes
diminished libido

Front 44

gonadotropin relared drugs fnx?

Back 44

reg release of gonadal steroid hormones
used in tx of infertility in men and women

Front 45

gonadotropin relared drugs related substances?

Back 45

menotropins
human menopausal gonadotropin = hMG

chorionic gonadotropin
(hcg)

urofollitropin

follitropin

Front 46

menotropins

Back 46

hMG
obtained from urine of post menopausal women containing FSH AND LH

Front 47

chorionic gonadotropin

Back 47

hcg
placental hormone
secreted in urine
structurally related to LH

Front 48

urofollitropin

Back 48

FSH OBTAINED from post menopausal women without any LH

Front 49

follitropin

Back 49

alpha and beta = human FSH products
synthesized by recombinant DNA

Front 50

gonadotropin relared drugs , substance administration?

Back 50

all = injected via IM , subcutaneous

Front 51

injection of hMG and FSH particulars? and subsequent inj of ? causes?

Back 51

period of 5-12 days
causes ovarian follicular growth and maturation

hCG

ovulation occurs

Front 52

gonadotropin relared drugs: men lacking gonadotropins treatment ? causes? subsequent inj?

Back 52

hCG

external sexual maturation

hMG or follitropin results in spermatogenesis

Front 53

gonadotropin relared drugs: related substances adverse effects women? men?

Back 53

ovarian enlargement
possible hypovolemia
multiple births

gynecomastia

Front 54

prolactin related drugs: prolactin fnx?

Back 54

stim and maintain lactation
reults in sexual drive
reproductive fnx decrease

Front 55

hypoprolactinemic conditions?

Back 55

no synthetic preparation available.

Front 56

hyper prolactinema ass with galactorrhea and hypogonadism tx with?

Back 56

bromocriptine

cabergoline

Front 57

bromocriptine
cabergoline also used to tx ? AE ?

Back 57

pituitary microadenoma
macroprolactinomas
hyperprolactinemia


nausea
headache
possible psychiatric problems

Hint 57