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21 Cards in this Set
- Front
- Back
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A1 action on Blood vessels
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Decrease venous return
Decrease BP Decrease PVR Used for primary systemic HTN |
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A1 use on heart failure
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Decrease Preload/afterload
Increase CO Decrease pulmonary congestion Tolerance occurs over a long term |
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Raynaud's Disease
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Painful Vasoconstriction of didgets
Use A1 to Decrease incidence of vasospasm |
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Phaeochromocytoma
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Tumor that causes intermittent HTN
Use A1 to treat HTN in prep for surgery |
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A1 action on urinary tract
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Relaxes tissues
Decrease resistance to urine flow Hypertrophy (tissues get bigger) causes squeeze of ureter |
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Impaired bladder emptying
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Use a1 to Decrease resistance in Spinal injury / BPH
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First Dose Phenomenon
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Postural Hyptension/syncope after 1st does of A1 antag b/c block sympathetic constriction of veins.
Occurs 30-90 minutes after dosing. Increase dose slowly Give QHS |
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A2 Antag action on CV
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Increase HR/contractility
Constict blood vessels Increase sypmathetic outflow |
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A2 antag action on Penile function
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Increase penile blood inflow
Decrease penile blood outflow Used with papaverine for erection. |
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B-antag on CV
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B1- Dencrease HR, Contractility, Conduction
B2-Decrease HR Has little effect in normal heart |
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B-antag on Cardiac conduction
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Decrease rate of depolarization of ectopic pacemakers
Decrease AV conduction Increase Refractory period of AV node decrease Sinus rate decrease HR |
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B2 antag on Blood vessels
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Vasoconstriction
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B1 on kidney
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Decrease Renin secretion
Decrease PVR Decrease Fluid retention/ BP |
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Angina
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Imbalance in O2 supply vs. demand.
B antag Decreases myocardial O2 needs --> prevents symp activation of heart |
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MI
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Use b-antag to:
Decrease O2 demand Antidysrhythmic actions Atenolol/propranolol - early stages propranolol, timolol, metoprolol- prevent recurrences. |
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Ventricular Dysrhythmias
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Use b antag to decrease av node conduction
decrease rate of SA node |
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B2 on respiratory system
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bronchoconstriction
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B antag on metabolic
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B2- decrease gluconeogenesis, glycolysis.
Adverse effect on glucose mobilization Covers important indicators of hypoglycemia (tremor, tachycardia) |
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B antag on eye
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Decrease aqueous humor production by ciliary body --> Decrease interocular pressure
used for open angle glaucoma |
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B antag on pheochromocytoma
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Decrease dysrhythmias
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B antag on hyperthyroidism
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Decrease symp effects by inhibiting T4 to T3
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