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84 Cards in this Set
- Front
- Back
T or F? Meningiomas often incite an osteoblastic reaction in the overlying cranial bones
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True
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Negri bodies?
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Rabies
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T or F? Glioblastoma is an astrocytoma
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True
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Which tumor can cause a butterfly lesion crossing between the cerebral hemispheres?
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Glioblastoma multiforme
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Tumor with whorls of cells and scattered psammoma bodies..
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Meningioma
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VDRL?
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Syphilis
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Subarachnoid hemorrhage and/or seizures involving the cerebral hemispheres
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AV malformation
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Tuberous sclerosis?
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Neurocutaneous disorder - tubers (hamartomas in the brain, skin, pancreas, and cardiac rhabdomyomas
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Cerebellar angiomas associated with...
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von Hippel-Lindau
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Nevus flammeus associated with..?
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Sturge-Weber (port-wine nevus_
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T or F? Intermittently raised pressure hydrocephalus classically causes memory loss, urinary incontinence, and gait abnormalities
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True
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Failure of upward gaze?
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Pinealoma
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Bilateral loss of pain and temp sensation in the upper extremities - what malformation?
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Arnold-Chiari --> syringomyelia
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The atrophy in Pick's disease affects which lobes?
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Frontal, temporal
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Classic triad of Parkinson's
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Tremors, rigidity, and akinesia
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Anterograde amnesia and confabulation
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Korsakoff syndrome
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Subependymal giant cell astrocytoma
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Tuberous sclerosis
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Describe primary CNS lymphoma lesions in AIDS patients?
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Multicentric, may involve leptomeninges
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T or f? Friedreich's ataxia is related to atrophy of the spinal cord.
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True
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Cystic brain lesion filled with dark, oily fluid...
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Craniopharyngioma
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Half of all intraparenchymal hemorrhages involve the...
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Basal ganglia and internal capsule
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Demyelination of the......can follow overly rapid correction of severe hyponatremia?
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central ponsq
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Arnold-Chiari type 2?
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More severe, cerebellar vermis and medulla are displaced through the foramen magnum
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Elongated intracytoplasmic neuronal inclusions
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Negri bodies --> rabies
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Intracytoplasmic spherules composed of paired helical filaments?
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Pick bodies
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Multinucleated giant cells are typical in which viral encephalitis?
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HIV encephalitis
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Fried egg cells in a brain tumor?
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Oligodendroglioma
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Histologic progression of MS
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1. Acute - Lymphohistiocytic infiltration and myelin breakdown
2. Hyperplastic gliosis (astrocytosis) - GEMISTOCYTES |
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Brain tumor in kids with evidence of both neuronal and glial differentiation?
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Medulloblastoma
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Associate neurofibromas with...?
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Neurofibromatosis type 1
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Associate meningiomas with...?
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Breast cancer, high estrogen states
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Associate acoustic neuromas with...?
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Neurofibromatosis type II
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definition of papilledema?
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Swelling of the optic disk usually due to increased ICP
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How do Abscesses look on CT?
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White rings around black low-attenuation centers in the brain...?
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What could explain a catastrophic hemorrhage in an Alzheimer's patient?
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Amyloid angiopathy
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Corkscrew-shaped eosinophilic fibers
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Rosenthal fibers - seen in pilocytic astrocytoma, reactive gliosis
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Paired helical filaments in neurofibrillary tangles are due to...?
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Abnormal phosphorylation of tau
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Retinal angioma in which syndrome?
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von Hippel Lindau
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This brain tumor shows necrosis and hemorrhage on biopsy...
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Glioblastoma multiforme
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Location of glioblastoma in adults? Kids?
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Adults - cerebral cortex
Kids - Brainstem |
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Ki-67
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nuclear factor - used to determine neoplastic replicative activty
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HSV encephalitis affects which parts of the brain?
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Lower portions of cerebral cortex --> temporal lobes and base of the frontal lobes
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chorda tympani branch of VII controls salivation from...?
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submandibular and sublingual glands
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Which nerve runs closest (laterally) to the pituitary?
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Abducens
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Which nerve lies in the tonsillar fossa?
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Glossopharyngeal
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Which cranial nerves emerge from the cerebellopontine angle?
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Facial and vestibulocochlear
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Which nerve moves the hyoid bone anteriorly to open the pharynx?
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C1 - ansa cervicalis
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Olfactory bulb sends axons to...?
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Pyriform cortex
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Median nerve passes through which muscle after the elbow?
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Pronator teres
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Satiety center?
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Ventromedial nucleus
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Locked-in syndrome is caused by a lesion in...
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the pons (ventral)
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What passes through the greater sciatic foramen?
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Superior gluteal nerve (above the piriformis) and the sciatic nerve (below the piriformis
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Parinaud's syndrome
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Affects vertical gaze center - dorsal midbrain (superior colliculi)
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Which nerve is required to make the 'kuh' sound?
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Vagus - raises the palate
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Nail of the index finger is innervated by...?
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Median nerve
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chemoreceptor trigger zone - located where?
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floor of 4th ventricle
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Innervation from upper part of posterior pharynx? Lower part?
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IX
X |
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Myasthenia gravis mechanism
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Autoimmune damage to the acetylcholine receptor in the NMJ
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CMV lab work
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India ink
Urease positive |
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Subacute sclerosing panencephalitis
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Rare late complication of measles infection at an early age
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Which two amoeba have a propensity for causing meningoencephalitis?
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Naegleria fowleri and Acanthamoeba
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Neuroepithelial cells?
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Astrocytes and oligodendrocytes (both derived from glioblasts)
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Chlamydia induced blindness
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Corneal infection, then scarring
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Ventriular-peritoneal shunt infection?
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Staph epidermidis
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Mississippi river bed yeast
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Crypto
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Embolization from infective endocarditis typically causes abscesses in which lobe?
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Parietal
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Most likely cause of active toxo infection?
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Reactivation of latent infection
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neostigmine mechanism of action?
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carbamylation of AChesterase
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Primidone has a cross-sensitivity to...?
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Phenobarbital
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OD on TCAs could cause/
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Lethal arrhythmias
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Immediate lowering of intraocular pressure?
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Acetazolamide
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Phenelzine?
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MAO inhibitor
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Trihexyphenidyl?
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Anti-muscarinic used in Parkinson's
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HTN emergency?
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>130 mm HG DIASTOLIC pressure
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Mechanism of sumatriptan?
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Serotonin agonist
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Reinforcing effects of ampethamines caused by?
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Dopamine release
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Which antidepressant is contraindicated in patients with bulimia or anorexia?
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Bupropion
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Neorucyticercosis?
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Taenia solium infection (cysts are involved in the CNS)...most common parasitic infection of the CNS... most frequently encountered in Mexico, Southeast Asia, etc.
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Strep agalactiae?
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Group B strep
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Alar plate forms what?
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dorsal spinal cord
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Bilateral acoustic neuromas are associated with...?
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Neurofibromatosis type II --> 22qn (all the 2's...bi-lateral, nfm type 2, 22q, etc)
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Perivenous microglial involvement with demyelination...?
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Post-infectious (ie measles) encephalomyelitis
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encysted bradyzoites?
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toxoplasmosis
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Anterolateral part of the spinal cord affects which muscle group?
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Distal extensors
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