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4 Cards in this Set
- Front
- Back
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Botulinum toxin |
Acts on: Cholinergic nerve terminal
Mechanism: Enzymes that cleave Cholinergic nerve terminal proteins; block ACh release from nerve terminals
Clinical Applications: Muscle spasms Smooth wrinkles Reduce excessive sweating |
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Edrophonium |
Acts on: AChE
Mechanism: AChE inhibitor; readily reversible
Clinical applications: 1) Reversal of neuromuscular block by non-depolarizing drugs 2) Diagnosis of myasthenia gravis |
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Pyridostigmine |
Acts on: AChE
Mechanism: Inhibits AChE; quarternary ammonium carbamate ester
Clinical application: Treatment of myasthenia gravis |
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Acetylcholine |
Acts on: nAChR
Mechanism: Cholinergic agonist (muscarinic and nicotinic)
Clinical Applications: Cataract (and other eye) surgery |
