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30 Cards in this Set

  • Front
  • Back

Blood

CT composed of liquid portion (plasma~55%) and a cellular portion consisting of various types of cells and cell fragments (formed elements ~45%)


Chief means of transport within the body

Functions of Blood

transport of gases, nutrients, hormones, heat, and wastes, regulation of pH, body temp, and H2O content of cells, anti-clotting mechanism, and body defenses

Composition of blood

plasma- watery liquid containing dissolved substances


Formed Elements- cells and formed elements (99% RBCs and 1% WBCs and Platelets)

Buffy Coat

white blood cells and platelets, in between plasma and RBCs



Plasma

92% H2O and 8% solutes, "internal environment for cells", collected with anti-coagulants in purple tops

Composition of Plasma

Na, K, Cl, Glucose, Proteins (Albumin, Globulin, Fibrinogen), Liquid, ions, hormones, and gases

Serum

Plasma minus clotting factors, blood sample clots, watery component oozes out of clot and collects around it


Collected w/o anti-coagulants in red top

Purple Top

EDTA

Cells in Blood

Erythrocytes, Monocytes, Eosinophils, Platelets, Lymphocytes, Neutrophils, and Basophils

Erythrocytes

biconcave shaped, contains Hb, live ~120 days, formed in bone marrow of long bones, mature RBC's have no nucleus, transport O and CO2

Erythros

Greek, "Red"

WBCs

Leucocytes, nucleated cells, combat infection, start inflammation, two types: granulocytes and agranulocytes


Increased- infection, inflammation


Decreased- indicative of an overwhelming infection of sepsis

Leucos

Greek: white

Stain for WBCs

Wright's Stain

Granulocytes

Neutrophils (both dyes), eosinophils (allergy/parasites), and basophils

Agranulocytes

Monocytes, and lymphocytes

Platelets

Thrombocytes, disc-shaped, no nucleus, parent cell: megakaryocyte, release substances to stimulate clotting and constriction of blood vessels


Decreased- problem with production in the bone marrow, or they're being used up due to disease condition


Increased- indicate an activated bone marrow, exertion, or excitement

Thrombus

Clot

Coagulation

vasoconstriction, platelet plug formation, fibrin network

Anticoagulants

Heparin/warfarin (sweet clover poisoning)/coumadin, EDTA (manmade), Citrate (transfusion bags), Oxalate (diabetics)

Company that makes the vacutainer tubes for blood collection

Becton Dickinson

Red tube tops have a ____ coating to provide ample surface for the blood cells to adhere

Silica

What protein is the most abundant in plasma

Albumin- osmotic pressure

Green top

lithium and sodium heparin

Tan top

sodium heparin (glasS)


spray coated K2 EDTA (plastic) for lead determinations

Blue top

sodium heparin (glass) Na2 EDTA (glasS) none (glass), for toxicology and nutrient determinations

Yellow top

Acid citrate dextrose and sodium polyanethol sulfonate

MCHC

mean corpuscular hemoglobin concentration- concentration of hemoglobin in a given volume of packed RBCs

Hematocrit

(HCT) "PCV or packed cell volume" is the amount of RBCs in the blood


Increased- dehydration


Decreased- indicative of anemia from parasitism, nutritional deficiencies, or chronic disease (EX: liver disease, cancer)

Globulin

alpha,beta, and gamma (antibody) fragments