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15 Cards in this Set
- Front
- Back
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Histamine has four types, what are they?
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1) H1 CaMP 2) Phospholypase c 3) Adenylyl Cyclase inhibition 4) Phospholipase C
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H2 effects mainly the...
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heart and GI
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H1 has three effects
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Redness (arterioles)
wheal (venules) Flare (nerves, h1 acts on nerves, this causes itching and such) |
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Why would we inject someone with Histamine?
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For diagnostic purposes, for Asthma, for GI disorders, most often not because of the heavy side effects though. Inject intradermal HIstamine Phosphate.
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What are the peripheral effects of a Histamine 1 antagonist? There are lots
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Block GI secretions, inhibit vasodilation, inhibit increased vascular permiability, inhibit severe anaphylactoid reactions.
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H1 antagonists effects not related to actual h1 blockage...
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due mainly to blockage of anti muscarinic effects. Anti nausea (
best if ised prophylactically) anti emetic, sleep agent (think benedryl) |
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Ethanoloamines h1 antagonists drugs are...
ethan Manizone is.... |
DIVES off CLIFFS and DOCKS.
diphenhydramine, clistamine, doxylamine. these drugs are highly sedative benadryl and great for motion sickness. |
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Ethylenediamenes drugs...
diamonds.... |
I TRIPPED over a PILE of DIAMONDS.
tripelenammine, pyrilamine. These drugs are more selective for h1, have moderate anti muscarinic effects but have GI side effects common. Moderate sedation. |
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alkylamines drugs...
Alcohol.... |
BROM drank ALCOHOL and CHLOROX and started TWEAKING
brompheniramine, chlorpheniramine, are the alkylamines. these cause tweaking or CNS stimulation. |
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Piperazines....
PIPER... |
PIPER pipes all night long fight off COLD. Has one CAMELBACK (for hydration) and a METS hat.
long lasting, anti pruretic effects. hydrazine and meclizine |
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Phenothiazines....
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Cant think of anything for phenothiazine. It is great for anti muscarinic effects though. Its main drug is promethazine (we met him earlier in the anti emetic drugs) and he will knock you out with his sedating effects.
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Piperadines...
PIPER at DINER |
2 PIPERS at the DINER battles over their TURF by putting STEMS in their ears. They drank Alcohol and they both DIED!!! Fight over which was nice.
second generation piperadines drugs are terfenidine and astemizole. these must be metabolized first and dont have any cns effects therefore they dont make you drowzy, which is nice. Both drugs though look to have been withdrawn. |
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Loratadine
BORAT at DINER |
BORAT at the DINER eats PROTEIN shakes ONCE a day for his HEART.
loratidine is highly protein bound, you take it once a day and it doesnt cause aryythmias. |
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cetirizine
Sit and read a magazine |
SIT and read a MAGAZINE about HYDROXYCUT.
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fexofanadine...
fox on the turf |
FOX on the TURF
fexofanadine is the second generation of the turfenedine without all the problems of the 1st generation. Nice. |
