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84 Cards in this Set

  • Front
  • Back

Velocity of blood flow through a given vascular segment varies with...

...the total cross sectional area of that segment

As the sum of the cross sectional area increases...

...velocity of blood flow often decreases

The total cross sectional area of vessel segments increases from...

...aorta to the capillaries

The total cross sectional area of vessel segments decreases from...

...capillaries to the aorta

The velocity of blood flow decreases from...

...aorta to the capillaries

The velocity of blood flow increases from...

...capillaries to the vena cavas

What does the low blood velocity in the capillaries maximize?

The low blood velocity maximizes the amount of time available for transcapillary exchange

In consecutive vascular segments the mean blood pressure...

...decreases

Mean blood pressure is highest...

...in the aorta

Mean blood pressure reaches its lowest values in...

...the vena cavas

The greatest decrease in mean blood pressure occurs in...

...arterioles

Despite the greatest drop in mean blood pressure occurs in the arterioles, it does not have the lowest blood pressure because...

...they are the vessels with the greatest amount of resistance

What are present in the walls of the arteries that prevents the the mean blood pressure from dropping to 0?

Elastic fibers

As blood travels through the capillaries...

...blood pressure slowly decreases

Where is the skeletal muscle pump present?

In medium size veins

How does the skeletal muscle pump function?

When skeletal muscles contract, they shorten up and bulge out, squeezing the vein and increasing the blood pressure, thus moving blood in the veins.

When the skeletal muscle pumps blood...

...the valve closest to the heart opens, while the valve furthest from the heart stays closed.

When do varicose veins occur?

When the valves in veins become stretched and do not close properly

At any instant, most blood volume is contained where?

In the peripheral veins surrounding organs

What are the 3 layers of tissue that are found in every blood vessel?

1. Tunica interna, 2. tunica media, and 3. tunica externa

What do veins lack, but arteries have?

Elastic lamina

What causes arteries to be to be resistant and round?

The internal and external elastic lamina found in the tunica interna and tunica media, respectively.

Why don't veins hold a definitive shape?

Because they lack elastic lamina

What kinds of vessels are veins?

Capacitance (storage) vessels (i.e. they store blood)

Where does nutrient and waste exchange between the tissues take place?

In the capillaries

What allows for substances to easily diffuse across a capillary?

A 1 cell layer thick endothelium

What is a basement membrane?

A thin layer of connective tissue that surrounds a capillary

What characterizes a continuous capillary?

Very small spaces between endothelial cells and a complete basement membrane

Where are continuous capillaries found?

In nervous tissue, skeletal muscle tissue, and adipose tissue

What characterizes a fenestrated capillary?

There are large pores in the wall of the endothelium and a complete basement membrane

What do the pores of a fenestrated capillary allow for?

Increased ease of movement of substances across the membrane

Where are fenestrated capillaries found?

In endocrine glands, the kidneys, and the digestive tract (particularly the small intestine)

What characterizes a discontinuous capillary?

Wide gaps in the endothelium and an incomplete basement membrane

Where are discontinuous capillaries found?

In the liver and the spleen

What is the movement of water and dissolved solutes from the blood, across the capillary membrane, to the interstitial space?

Filtration

Where does the greatest amount of filtration take place in the capillary?

At the arterial end of the capillary

What is the movement of water and dissolved solutes from the interstitial space, across the capillary membrane, back into the blood?

Reabsorption

Where does the greatest amount of reabsorption take place in the capillary?

At the venous end of the capillary

What are the two kinds of pressures involved in filtration and reabsorption?

1. Hydrostatic pressures and 2. osmotic pressures

What is hydrostatic pressure defined as?

Pressure that fluid is exerting on the walls of a vessel

What is osmotic pressure defined as?

The strength by which a solution draws in water across a membrane

As the concentration of solution increases...

...osmotic pressure increases

What is Intercapillary Hydrostatic Pressure?

Blood pressure within the capillary

What is intercapillary hydrostatic pressure also known as?

Blood hydrostatic pressure

As blood travels from the arterial end to the venous end, blood pressure...

...decreases (35 mmHg -> 15 mmHg)

What process does intercapillary hydrostatic pressure contribute to?

Filtration

What is Interstitial (fluid) Hydrostatic Pressure?

Fluid pressure outside of the capillary

What process does interstitial (fluid) hydrostatic pressure contribute to?

Reabsorption

In order to have osmotic pressure...

...solutes must be present (blood and hemolymph)

What contributes to plasma osmotic pressure (POP)?

Proteins within the blood

What process does plasma osomtic pressure contribute to?

Reabsorption

Why is interstitial (fluid) osmotic pressure (IOP) less than plasma osmotic pressure (POP)?

There are not as many large solutes present in the interstitial space

What process doe interstitial osmotic pressure contribute to?

Filtration

What is the sum of filtration pressures equal to?

Intercapillary hydrostatic pressure + Interstitial osmotic pressure

What is the sum of reabsorption pressures?

Plasma osmotic pressure + Interstitial hydrostatic pressure

When the sum of filtration pressures > the sum of reabsorption pressures...

...filtration occurs

When the sum of filtration pressures < the sum of reabsorption pressures...

...reabsorption occurs

When the sum of filtration pressures = the sum of reabsorption pressures...

...there is no net movement

What is edema?

A situation in which bodily tissues contain an excessive amount of hemolymph between cells, causing swelling.

What are some causes of edema?

Systemic hypertension, trauma to the tissue, a decrease in [plasma protein], and poor lymphatic drainage

If blood pressure is high enough, there may be more filtration down the length of the capillary, therefore...

...there is an increase in intercapillary hydrostatic pressure

Trauma in the tissue causes the release of many chemicals, one such is histamine. What does histamine do?

It causes vasodilation and increases vascular permeability. Therefore, proteins move out of blood and into interstitial space, decreasing reabsorption.

What happens when there is a decrease in [plasma proteins]?

There is a decrease in plasma osmotic pressure. Therefore, there is a decrease in reabsorption.

What two factors contribute to mean arterial blood pressure?

Total peripheral resistance and cardiac output

What is total peripheral resistance?

The impedious (resistance) to blood flow

What is cardiac output?

It is equal to stroke volume

What are some factors that can influence total peripheral resistance?

Blood viscosity, length of blood vessels, and vascular diameter

An increase in blood viscosity...

...results in an increase in total peripheral resistance, which increases mean arterial blood pressure

A decrease in blood viscosity...

...results in a decrease in total peripheral resistance, which decreases mean arterial blood pressure

What can increase blood viscosity?

Polycythemia

An increase in the length of a blood vessel...

...results in an increase in total peripheral resistance, which increases mean arterial blood pressure

A decrease in the length of a blood vessel...

...results in a decrease in total peripheral resistance, which decreases mean arterial blood pressure

An increase in vascular diameter...

...results in a decrease in total peripheral resistance, which decreases mean arterial blood pressure

A decrease in vascular diameter...

...results in an increase in total peripheral resistance, which increases mean arterial blood pressure

What is the vasomotor center?

A group of neurons within the medulla oblongata that influences vasodiameter

What connects the vasomotor center to blood vessels?

Sympathetic nerve fibers

An increase in the frequency of action potentials...

...results in vasoconstriction, which increases blood pressure

A decrease in the frequency of action potentials...

...results in vasodilation, which decreases blood pressure

What is the function of barroreceptors?

To monitor tension on vessel walls caused by blood pressure

When blood pressure changes, what is the response of the barroreceptors?

The propagate action potentials up to the vasomotor center telling it to constrict or dilate vessels

What is microcirculation?

Circulation through the capillary bed

In order to regulate blood flow through the capillary...

...the pre-capillary sphincter must relax or contract

When the pre-capillary sphincter is relaxed...

...there is blood flow through the capillary bed

When the pre-capillary sphincter is contracted...

...there is no blood flow through the capillary bed