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82 Cards in this Set
- Front
- Back
What are the three major functions that animals use their absorbed chemical energy for?
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1. biosythesis
2. maintenance 3. generation of external work |
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Energy transfers are always ___
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inefficient
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Whenever high grade energy is transformed to another, some energy is converted into ___
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heat
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What is the bi-product of high grade, chemical bond energy?
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heat
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metabolism
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the sum of the body's total biochemical reactions
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anabolism
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synthesis of organic molecules storage of energy
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catabolism
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the breakdown of organic molecules into simpler compounds to release the energy stored in chemical bonds
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definition of metabolic rate
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rate of energy consumption: the rate at which chemical energy is converted to heat and external work
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energy is measured in
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joules or calories
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metabolic rates are expressed in
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calories per unit time or watts
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3 importances of metabolic rate
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1. food
2. activitiy 3. ecological drain |
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how is metabolic rate measure?
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direct and indirect calorimetry
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what is indirect calorimetry?
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1. respiratory exchange (oxygen consumption)
2. material-balance method (measuring chemical energy content of matter that enters and leaves the body) |
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what is the most common way to measure metabolic rate?
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respiratory exchange/oxygen consumption
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Break down of glucose:
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1 glucose + 6 oxygen = 6 carbon dioxide + 6 water +
energy 686 kcal |
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basal metabolic rate
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used to measure metabolic rate of endotherms
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basal metabolic rate is used to measure endotherms when they are:
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1. in its thermoneutral zone
2. fasting 3. resting |
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standard metabolic rate is used to measure:
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ectotherms while they are
1. fasting 2. resting |
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standard metabolic rate is specific to
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body temperature
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metabolic rate scales like
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.75
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large animals have ___ mass-specific metabolic rates than smaller animals
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lower
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transport work
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the work of transporting materials through membranes
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mechanical work
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general work or movement, the beating of cilia, the movement of chromosomes, and the contraction of muscles
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chemical work
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anabolic and catabolic reactions
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energy is stored in
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chemical bonds
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energy is released when
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the bonds are broken
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three main energy carriers
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NADH, NAD+, and ATP
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NADH
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the reduced form stores energu
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NAD+
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the oxidized form releases energy
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ATP
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the most versatile energy carrier
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why is atp such a suitable energy carrier?
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1. bc of its structure
2. bc of it can be recycled |
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what are 4 energy storage molecules
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1. glucose/carbohydrates
2. fats - fatty acids and triglycerides 3. proteins 4. nucleic acids |
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glucose is stored in the cell as
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glycogen
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4 main points about glucose:
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1. central to energy *metabolism
2. is *derived from diet, from glycogen, or can be synthesized from the cell (gluconeogenesis) 3. precursor to form most *carbohydrates 4. *cells require glucose |
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energy is used when it is in the form of
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ATP
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energy is stored when it is in the form of
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complex molecules, carbohydrates, fats, and proteins
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lipids posses how many more times of energy than carbohydrates?
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10
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what are the 3 kinds of lipids
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1. fatty acids]
2. triglycerides 3. phospholipids |
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order of preferance of fuel
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1. carbohydrates: glucose and glycogen
2. lipids 3. proteins |
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cellular respiration is
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the biochemical process of energy production
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glycolysis con
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low energy yield, only yields 2 moles of ATP per 1 mole of glucose
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glycolysis pros
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1. rate of atp production is fast
glycolysis is preferred when immediate energy is needed 2. does not require oxygen - glycolysis can proceed under anerobic conditions |
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4 main steps to oxidative metabolism
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1. acetyle coa
2. tricarboxylic acid cycle (krebs cycle) 3. electron transport system (ets) 4. oxidative phosphorylation |
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TCA cycle
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acetyl coa -> co2 and reducing equivalent NADH and FADH2 and GTP
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ETS
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reducing equivalents are oxidized to release energy and generate a proton gradient
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oxidative phosphorylation
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atp synthesis
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what are the products of oxydative phophorylation?
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1. oxygen gradient
2. heat 3. reactive oxygen |
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chemiosmosis
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the coupling of electron transport chain to atp synthesis
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atp synthase
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only place where H+ diffuses back into the mitochondrial matrix
input of H+ cause the cylindrical rotor to move and causes change in catalytic region which causes adp and inorganic phosphate to make atp |
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summarize glycolysis
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glucose to pyruvate, its anerobic
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glycolysis sum exchange
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1 mole glucose = 2 mole pyruvate, 2 moles atp
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con of glycolysis
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low energy yield
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pros of glycolysis
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1. fast
2. absence of oxygen |
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what happens with metabolism in the absence of oxygn
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glycolysis becomes the main source of energy. lactic acid and causes muscle fatigue
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what is actually happening in TCA cycle
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acetyl coa -> c02 FADH and NADH and gtp
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purpose of the electron transport chain
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the reducing agents become oxidized and a protein gradient is formed
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what does complex 5 of the electron transport chain do?
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carried the chemiosmotic pump run by protons going through and formation of atp
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chemiosmosis
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the coupling of the electron transport chain to the atp synthesis
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what about atp structure makes it a good energy carrier?
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1. high energy phosphate bonds
2. negative charge makes them unstable 3. instability make them easy to release energy 4. energy is released when atp is hydrolized into adp |
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what two tissue store the most glycoge?
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liver and muscle
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which tissue is capable of releasing glycogen directly intot he blood stream?
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liver
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what does muscle need in order to release glycogen into the blood?
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glycogen-6-phosphatase converts glycogen back into glucose first
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what is the main lipid storage form of energy?
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triglycerides
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phospholipids are broken down by
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phospolipases
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tryglycerides are broken down by
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lipases
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tryglycerides are stored in
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adipose tissue
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intermedietary metabolism
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generate fuel (glucose, amino acids) for cellular respiration (energy metabolism)
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3 things about glycolysis
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1. first step in catabolism
2. occurs in cell cytoplasm 3. occurs in the absence of oxygen |
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glycolysis: 1 glucose yields
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2 pyruvate + 2 atp
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TCA cycle: 2 mole pyruvate yields
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36 mole atp
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in anerobic conditions, what pyruvate used for?
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yeast and bacteria ferment to get ethanol
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where does ets occur?
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within inter mitochondrial membrane
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oxidation reaction:
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4e-+4H+ + o2 = 2H2o
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what makes glucagon hormone?
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adrenal gland
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how does thyroid hormone influence thermogenesis?
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thryoid hormone can trigger the release of UCP3 and this increases energy expenditure by reducing metabolic activity
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role of hormone in intermediary metabolism
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glycogen synthesis, breakdown, and glucose synthesis (glucogenesis)
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insulin
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incr glycogensis + glucose utilization
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glucagon + epinephrine =
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inc glycogenolysis (breakdown glycogne polymer into monomer)
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what hormones can stimulate the conversion of glucose to pyruvate?
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glucagon and cortisol
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what is the phosphocreatine shuttle?
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the way atp is stored in the muscle. atp is stored in the form of phosphocreatine and the conversion is done with the enzyme CPK
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phophoscreatine = (atp)
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5-10 times of atp
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after exercise has stopped, extra oxygen is required to
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metabolize lactic acid and replenish atp, phosphocreatine and glycogen
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