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82 Cards in this Set

  • Front
  • Back
What are the three major functions that animals use their absorbed chemical energy for?
1. biosythesis
2. maintenance
3. generation of external work
Energy transfers are always ___
inefficient
Whenever high grade energy is transformed to another, some energy is converted into ___
heat
What is the bi-product of high grade, chemical bond energy?
heat
metabolism
the sum of the body's total biochemical reactions
anabolism
synthesis of organic molecules storage of energy
catabolism
the breakdown of organic molecules into simpler compounds to release the energy stored in chemical bonds
definition of metabolic rate
rate of energy consumption: the rate at which chemical energy is converted to heat and external work
energy is measured in
joules or calories
metabolic rates are expressed in
calories per unit time or watts
3 importances of metabolic rate
1. food
2. activitiy
3. ecological drain
how is metabolic rate measure?
direct and indirect calorimetry
what is indirect calorimetry?
1. respiratory exchange (oxygen consumption)
2. material-balance method (measuring chemical energy content of matter that enters and leaves the body)
what is the most common way to measure metabolic rate?
respiratory exchange/oxygen consumption
Break down of glucose:
1 glucose + 6 oxygen = 6 carbon dioxide + 6 water +
energy 686 kcal
basal metabolic rate
used to measure metabolic rate of endotherms
basal metabolic rate is used to measure endotherms when they are:
1. in its thermoneutral zone
2. fasting
3. resting
standard metabolic rate is used to measure:
ectotherms while they are
1. fasting
2. resting
standard metabolic rate is specific to
body temperature
metabolic rate scales like
.75
large animals have ___ mass-specific metabolic rates than smaller animals
lower
transport work
the work of transporting materials through membranes
mechanical work
general work or movement, the beating of cilia, the movement of chromosomes, and the contraction of muscles
chemical work
anabolic and catabolic reactions
energy is stored in
chemical bonds
energy is released when
the bonds are broken
three main energy carriers
NADH, NAD+, and ATP
NADH
the reduced form stores energu
NAD+
the oxidized form releases energy
ATP
the most versatile energy carrier
why is atp such a suitable energy carrier?
1. bc of its structure
2. bc of it can be recycled
what are 4 energy storage molecules
1. glucose/carbohydrates
2. fats - fatty acids and triglycerides
3. proteins
4. nucleic acids
glucose is stored in the cell as
glycogen
4 main points about glucose:
1. central to energy *metabolism
2. is *derived from diet, from glycogen, or can be synthesized from the cell (gluconeogenesis)
3. precursor to form most *carbohydrates
4. *cells require glucose
energy is used when it is in the form of
ATP
energy is stored when it is in the form of
complex molecules, carbohydrates, fats, and proteins
lipids posses how many more times of energy than carbohydrates?
10
what are the 3 kinds of lipids
1. fatty acids]
2. triglycerides
3. phospholipids
order of preferance of fuel
1. carbohydrates: glucose and glycogen
2. lipids
3. proteins
cellular respiration is
the biochemical process of energy production
glycolysis con
low energy yield, only yields 2 moles of ATP per 1 mole of glucose
glycolysis pros
1. rate of atp production is fast
glycolysis is preferred when immediate energy is needed
2. does not require oxygen - glycolysis can proceed under anerobic conditions
4 main steps to oxidative metabolism
1. acetyle coa
2. tricarboxylic acid cycle (krebs cycle)
3. electron transport system (ets)
4. oxidative phosphorylation
TCA cycle
acetyl coa -> co2 and reducing equivalent NADH and FADH2 and GTP
ETS
reducing equivalents are oxidized to release energy and generate a proton gradient
oxidative phosphorylation
atp synthesis
what are the products of oxydative phophorylation?
1. oxygen gradient
2. heat
3. reactive oxygen
chemiosmosis
the coupling of electron transport chain to atp synthesis
atp synthase
only place where H+ diffuses back into the mitochondrial matrix
input of H+ cause the cylindrical rotor to move and causes change in catalytic region which causes adp and inorganic phosphate to make atp
summarize glycolysis
glucose to pyruvate, its anerobic
glycolysis sum exchange
1 mole glucose = 2 mole pyruvate, 2 moles atp
con of glycolysis
low energy yield
pros of glycolysis
1. fast
2. absence of oxygen
what happens with metabolism in the absence of oxygn
glycolysis becomes the main source of energy. lactic acid and causes muscle fatigue
what is actually happening in TCA cycle
acetyl coa -> c02 FADH and NADH and gtp
purpose of the electron transport chain
the reducing agents become oxidized and a protein gradient is formed
what does complex 5 of the electron transport chain do?
carried the chemiosmotic pump run by protons going through and formation of atp
chemiosmosis
the coupling of the electron transport chain to the atp synthesis
what about atp structure makes it a good energy carrier?
1. high energy phosphate bonds
2. negative charge makes them unstable
3. instability make them easy to release energy
4. energy is released when atp is hydrolized into adp
what two tissue store the most glycoge?
liver and muscle
which tissue is capable of releasing glycogen directly intot he blood stream?
liver
what does muscle need in order to release glycogen into the blood?
glycogen-6-phosphatase converts glycogen back into glucose first
what is the main lipid storage form of energy?
triglycerides
phospholipids are broken down by
phospolipases
tryglycerides are broken down by
lipases
tryglycerides are stored in
adipose tissue
intermedietary metabolism
generate fuel (glucose, amino acids) for cellular respiration (energy metabolism)
3 things about glycolysis
1. first step in catabolism
2. occurs in cell cytoplasm
3. occurs in the absence of oxygen
glycolysis: 1 glucose yields
2 pyruvate + 2 atp
TCA cycle: 2 mole pyruvate yields
36 mole atp
in anerobic conditions, what pyruvate used for?
yeast and bacteria ferment to get ethanol
where does ets occur?
within inter mitochondrial membrane
oxidation reaction:
4e-+4H+ + o2 = 2H2o
what makes glucagon hormone?
adrenal gland
how does thyroid hormone influence thermogenesis?
thryoid hormone can trigger the release of UCP3 and this increases energy expenditure by reducing metabolic activity
role of hormone in intermediary metabolism
glycogen synthesis, breakdown, and glucose synthesis (glucogenesis)
insulin
incr glycogensis + glucose utilization
glucagon + epinephrine =
inc glycogenolysis (breakdown glycogne polymer into monomer)
what hormones can stimulate the conversion of glucose to pyruvate?
glucagon and cortisol
what is the phosphocreatine shuttle?
the way atp is stored in the muscle. atp is stored in the form of phosphocreatine and the conversion is done with the enzyme CPK
phophoscreatine = (atp)
5-10 times of atp
after exercise has stopped, extra oxygen is required to
metabolize lactic acid and replenish atp, phosphocreatine and glycogen