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63 Cards in this Set

  • Front
  • Back

What is an aldose

Carbonyl at end of carbon chain


In aldehyde group

What is a ketose

Carbonyl not at the end of carbon chain


In ketone group

What are isomers

mirror images around chiral carbons

What is the most common isomer form in CHO's in living organisms

D isomer

When does a CHO exist in a cyclical not straight chain structure

more than 5 C

Alpha anomer

-OH of anomeric (carbonyl) C is down

Beta anomer

-OH of anomeric (carbonyl) C is up

What is a CHO derivative

Hydroxyl group replaced with:


another substituent


carbon is oxidized


hydroxyl is phosphorylated

What are the 4 main CHO derivatives

1. Amino Sugars = -OH to -NH2



2. Deoxy Sugars = -OH to -H



3. Acidic sugars = -CH2OH to -COO-



4. Sugar phosphates = -OH to -OPO3-2-

4 main classifications of CHO's

1. Monosaccharides = simple sugar



2. Disaccharides = 2 monosacchrides



3. Oligosaccharides = 3~9 monosaccharides



4. Polysaccharides = 10+ monosaccharides

What determines the name of the glycosidic bond between two monosaccharides

1. Position of C involved



2. Anomeric configuration of those C's


(alpha "u" shaped, beta "s" shaped)

3 important disaccharides and their linkage

1. Maltose - glc(alpha1 to 4)glc



2. Lactose - gal(beta1 to 4)glc



3. Cellobiose - glc(beta1 to 4)glc

2 important starches and their likage

1. Amylose - glc(alpha1 to 4)glc - linear



2. Amylopectin - glc(alpha1 to 6)glc - branches


(24-30 residues)

How does glycogen structure differ from amylopectin

Similar structure but more frequent branching (8-12 residues)

Structure of cellulose, hemicellulose and pectin

Cellulose = glc(beta1 to 4)glc



Hemicellulose = heteropolysaccharide



Pectin = heteropolysaccharide

What is lignin

NOT a CHO



part of cell wall



complex polymer of aromatic alcohols

2 main places CHO's found

1. Endosperm



2. Plant cell wall

3 main components of cell wall and their function

1. Cellulose = individual chains form microfibrils



2. Hemicellulose & Pectin = cross link cellulose microfibrils



3. Lignin = bonded to cellulose and hemicellulose, like concreted surrounding steel rods (cellulose)

4 main functions of CHO's

1. Not essential



2. Provide source of energy



3. Starch and glycogen = energy storage



4. Plant cell wall

Where does most CHO digestion occur

Small intestine

Origin, Substrate, Action, and End products of:


Pancreatic amylase

Origin = pancreas



Substrate = Starch



Action = dextrins



End Products = Maltose, isomaltose, glucose

Origin, Substrate, Action, and End products of:


Maltase and Isomaltase

Origin = Sm Intestine



Substrate = Maltose, isomaltose



End products = glucose

Origin, Substrate, Action, and End products of:


Lactase

Origin = Sm Intestine



Substrate = lactose



End products = glucose and galactose

Origin, Substrate, Action, and End products of:


Sucrase

Origin = Sm Intestine



Substrate = sucrose



End products = glucose and fructose

_______ breaks alpha(1-4) bonds in amylose and amylopectin and yields ___, ____, and _____

Alpha-amylase breaks alpha(1-4) bonds in amylose and amylopectin and yields maltose, maltotriose and limit dextrins

______ cleaves ______ bonds as well as alpha(1-4) bonds at non-reducing ends of amylose/amylopectin and yields ________

Amyloglucosidase cleaves alpha(1-6) bonds as well as alpha(1-4) bonds at non-reducing ends of amylose/amylopectin and yields glucose

_______ cleaves alpha(1-4) bonds of maltose and yields ______

Maltase cleaves alpha(1-4) bonds of maltose and yields glucose

Where is the most absorption of CHO's

duodenum and ileum

What is the active transporter of Glucose

Sodium-glucose linked transoprter

What is the passive transporter of Glucose

Glucose transporter

What is the beginning and end products of Glycolysis and what is net products

Glucose to Pyruvate



2 ATP, 2 Pyruvate, 2 NADH

The conversion of _________ to _________ is the intermediate step between glycolysis and citric acid cycle and it yields _________

pyruvate to acetyl-CoA



yields 2 NADH/glucose or 1 NADH/pyruvate

What is the beginning and end products of the Citric Acid Cycle and what is net products

Acetyl-CoA to Co2



Yields: 4 CO2, 2 ATP, 6 NADH, 2 FADH2

What is the beginning and end products of Oxidative Phosphorylation and what is net products

NADH/FADH2 to ATP



Yields: 2.5 ATP/NADH or 1.5 ATP/FADH2

Which is a higher energy carrier, NADH or FADH2

NADH

In __________ pyruvate is converted to glucose

Gluconeogenesis

How does gluconeogenesis differ from glycolysis

glycolysis in reverse



requires 6 ATP equivalents



Oxaloacetate is and intermediate



Other enzymes differ

Another word for glycogen degradation is

glycogenolysis

What are the steps of glycogenolysis and what is yielded

1. Glycogen phosphorylase breaks alpha(1-4) bonds


2. Debranching enzyme breaks alpha(1-6) bonds



Yield: 1 glucose-1-P and conserves 1 ATP

What is another word for glycogen synthesis

Glycogenesis

What are the steps of glycogenesis

1. Glycogen synthase elongates alpha(1-4) chains of UDP-glucose


2. Glycogen branching enzyme forms alpha(1-6) branches



requires 2 ATP equivalents

What is the main point of glycogenesis

makes more non-reducing ends to increase sites for synthesis and degredation

What happens in the pentose phosphate pathway

1. Pentoses converted to corresponding sugar phosphates



2. Sugar phosphates then fed into glycolysis (EMP)

What is the total ATP yield from 1 molecule of Glucose

Total = 32


Glycolysis = 2 ATP, 2 NADH (5 ATP) = 7 ATP


A. CoA = 0 ATP, 2 NADH (5 ATP) = 5 ATP


C.A.C. = 2 ATP, 6 NADH (15 ATP), 2 FADH2 (3 ATP) = 20 ATP

______ secreted by ________ in response to high blood glucose

Insulin is secreted by pancreas in response to high blood glucose

________ secreted by ________ in response to low blood glucose

Glucagon is secreted by the pancreas in response to low blood gluose

5 effects of Insulin

1. increase glucose uptake


2. increase glycogen synthesis


3. decrease glycogen degredation


4. increase lipogenesis


5. decrease lipolysis

4 effects of Glucagon

1. decrease glucose uptake


2. increase glycogen degradation


3. increase glucoeogenesis


4. increase lipolysis

Approximately ______ percent of bacteria attached to feed particles

70 %

Are protozoa associated or attached

associated

What are the two steps to plant cell wall breakdown by gut microbes

1. Cellulolytics break down cellulose and hemicellulose into solubilized oligo and polysaccharides



2. Other species ferment to acetate, butyrate, methane and propionate

What are the 2 limits to hydrolysis by gut microbes

1. Rate - dependent upon surface area



2. Extent - dependent upon lignin

What are the steps to fermentation of CHO's by gut microbes and what is the ATP yield

1. Glucose to pyruvate



2. Pyruvate to SCFA, CO2, H2, and Methane



Yields 2-4 mol ATP per mol of glucose, plus extra for methane

What are the 4 most common abnormalities of CHO digestion

1. Malabsorption of of sucrose and lactose



2. Diabetes mellitus



3. Acute Acidosis



4. Chronic Acidosis or SARA (sub acute rumen acidosis)

What are the 3 types of diabetes

Type 1 = don't produce insulin, childhood diabetes



Type 2 = don't sense insulin



Gestational = don't sense insulin during pregnancy, most common in animals

What causes acute acidosis

abrupt transition from forage to grain, lactate accumulates and pH drops below 5.2


What microbes cause acute acidosis



What microbes alleviate it

Cause = streptococcus bovis



Alleviate = Megasphaera elsdenii

What causes chronic acidosis

After adaptation to high grain, chronic episodes of low pH b/w 5.2 and 5.6



no accumulation of lactate



poor rumination = poor salivation = poor liquid dilution rate = less VFA washed out = low pH

What is the way to tell if a cow has chronic acidosis

milk fat depression

What are the main 4 effects of chronic acidosis

1. Milk fat depression



2. Ulceration and scarring ofrumen wall



3. Migration of fusobacterium necrophorum from ruminal ulcers to liver



4. formation of liver abscesses

How can you treat chronic acidosis

increase fiber to stimulate rumination and increase pH

Most concentrates are high in _________

starch

Most forages are high in ________, ________ and ___________

cellulose, lignin and other cell wall components