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5 Cards in this Set
- Front
- Back
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Lithium |
Narrow Therapeutic index, 0.6 to 1.2 mEq/L. Hyponatremia increases its resorption in Renal Proximal convoluted tubule 20% of Creatinine clearance rate Thiazide diuretics increase levels. Mannitol / Acetazolamide decrease serum levels.
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HIV Parturient |
C-section lowers vertical transmission ruptured membranes > 4hrs, chorioamnionitis, stds increase vertical transmission, invasive procedures, breast-feeding Regional Anesthesia - no increased risk proven |
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Desmopressin |
helps to increase the level of von Willebrand factor (vWF) in plasma by promoting its secretion from Weibel–Palade bodies, the storage granules of endothelial cells.
monitor patients Factor vIII and vWF levels (60-80% ) good for surgery
antidiuretic property => water retention and hyponatremia. Good for type 1 useless for vWF type 2 (releases more defective vWF)
Rapid administration -> Flushing/hypotension
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von Willebrand's Disease |
Type 1 - quantitative defect Type 2 - qualitative defect, 4 diff phenotypes Type 3 - Complete deficit |
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Ketamine |
Analgesic Psychedelic NMDA (N-methyl-d-aspartate )receptor antagonist potent cerebral vasodilator increases the (CMR02) cerebral metabolic rate of oxygen consumption and (ICP) intracranial pressure centrally mediated sympathetic effect on the CNS (HR++ , BP++, Myocardial o2 consumption++) direct myocardial depressant |
