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6 Cards in this Set
- Front
- Back
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What is the mechanism of action for neuromuscular blockers?
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bind to alpha subunit -> depolarization -> muscle fasiculation
succinylcholine is the only drug |
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What is the mechanism of action of non depolarizing neuromuscular blockers?
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bind to alpha subunit but does not change configuration of receptor
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What factors prolong the actions of neuromuscular blockers?
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pH
hypercalceima antibiotics hypothermia neuromuscular disorders |
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What are side effects of anticholinesteraces such as physostigmine?
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bradycardia
GI hypermotility bronchospasm |
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What is the train of four? How often do you repeat it?
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Sending four supramaximal impulses to the animal and compare resulting twitch 1 to twitch 4
Every 10-20 seconds |
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What is the normal twitch ratio?
How many of the receptors need to be occupied to have a decreased twitch? |
1
75% |
