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35 Cards in this Set

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  • Back
What are general considerations of local anesthetics?
-use sterile solution and injection equipment
-always aspirate before injecting
-do not inject into infected and inflamed areas
What are local anesthetics?
tertiary amines connected to a aromatic ring
can be aminoesters - procaine
can be aminoamindes - lidocaine
How are local anesthetics metabolised?
enzymatic hydrolysis is the primary metabolic pathway

aminoesters hydrolyzed by plasma cholinesterases

aminoamides undergo N dealkylation and hydrolysis in hepatic ER
What are the onset of action and duration of lidocaine, mepivicaine and bupivicaine?
lidocaine 3-5 minutes: 1-2 hours
mepivicaine 5-10 minutes: 1.5- 3 hrs
Bupivacaine 20-30 minutes: 4-6 hours
What is the mechanism of action for local anesthetics?
inhibit voltage gated sodium channels

block activation of channel and prevent depolarization of cell membrane

can be in ionized form - water soluble
unionized form - free base and lipid soluble
What are adverse effects of local anesthetics?
-systemic toxiciity
-direct damage to tissues-neurotoxic and myotoxic
-allergic reactions
-methemoglobinemia benzocaine (cats)
What are the signs of CNS toxicity due to local anesthesia?
muscle twitching and convulsions
unnconciousness
coma
respiratory arrest
What are the signs of cardiovascular toxicity from local anesthetics?
blockade of sodium channels in purkinkinje fibers and myocardium depresses electrophysiologic and mechanical function of the heart

sinus bradycardia and sinus arrest

toxic doses causes vasodilation and hypotension

bupivacaine is sepecially cardiotoxic

never give bupivacaine IV
What local anesthetic should you never give IV?
bupivicaine
how do you treat systemic toxicity due to local anesthetics?
support ventilation and control convulsions
Where do you apply topical anesthesia, where is it effective?
less effective?
applied to skin or mucous membranes

very effective on mucous membranes of eyes, nose and mouth

less effective penetration of intact skin
Where do you apply infiltration anesthesia?
subcutaneous injection of small volumes of local anesthetics into tissues

diffusion into surrounding tissues anesthetizing nerve fibers and endings

incisional line block (linea alba)
inverted L block
soaker catheters - intermittant injections
What are peripheral nerve blocks?
infection in the immediate vicinity of individual peripheral nerves or nerve plexus

used for cranial nerves, cervical and thoracic nerves
lumbar and sacral nerves
What is an infraorbital nerve block used for?
upper dental arcade, upper lip, nose, dorsal aspect of nasal cavity soft and hard palates

used for extraction of canines, incisors and premolars
What is a maxillary nerve block used for?
ipsilateral upper dental arcade, maxilla
What is a mandibular nerve block used for?
ipsilateral incisors, canine tooth, premolars, skin and mucosa of the chin and lower lip
What is a mental nerve block used for?
rostral mandible, ipsilateral canine and incisors

middle mental foramen, ventral to the lower first and second premolars
What are examples of cervical and thoracic nerve blocks?
brachial plexus block
forelimb nerve block
forefoot block
intercostal nerve block
Where are the brachial plexus blocks?
C6,C7,C8 and T1

indicated for surgeries or injuries distral to mid diaphysis of humerus
What is a nerve stimulator?
a current applied to the needle as it is inserted into a patient

the closer the needle is to the nerve the less current is needed to stimulate the nerve

the principle of a nerve stimulate can be used to locate any nerve not just the brachial plexus
What are the uses of forelimb blocks?
anesthesia of front leg distal to elbow joint-radial , ulnar and metacarpal fractures

four point block
median, ulnar, musculocutaneous nerves
radial nerve
What are the uses of a foot block?
provides anesthesia distal to carpus common for a declaw

insert needle on dorsomedial aspect of carpus just proximal to joint
-median nerve and palmar and dorsal cutaneous branches of ulnar
What are the uses of lumbar and sarcal nerve blocks?
anesthesia of hind leg distal to hip, saphenous, common peroneal and tibial nerve block
What is the saphenous nerve and what does it do?
saphenous = branch of femoral nerve that is sensory to medial surface of the thigh, stifle and lower leg
What does the common peroneal nerve do?
branch of the sciatic nerve

sensory to the dorsal aspect of lower leg

identify the fibula and inject dorsal and posterior to head of fibula
What does the tibial nerve do?
branch of sciatic nerve

sensory to caudal aspect of lower leg
Id medial and lateral heads of the gastrocnemius and inject in between
What are indications for hindlimb nerve blocks?
procedures from stifle distally (including stifle)
What are indications of an infraorbital nerve block in large animals?
anesthesia of upper lip and nose for suturingnasal laceration

placement of a nose ring in cattle
What are indications of a auriculopapebral block in large animals?
used in horses and cattle for examination and treatment of eye

blockade of auriculopalpebral nerve (motor) akinesia of eyelids
What are the indications of the supraorbital nerve block?
sensation to upper eyelid

nerve emerges from supraorbital foramen
What are the indications for peterson and retrobulbar blocks?
enucleation of eyeball, removal of tumors from eye and eyelids
What are the indications for a caudal epidural?
for surgical procedures involving tail, perineum, anus, rectum, vulva, prepuce and skin of the scrotum
-injection of small volume of LA into epidural space at either sacrococcygeal or first intercoccygeal space
What are the indications for cranial epidurals?
use lidocaine or bupivacaine

analgesia as far as T5 in dogs

dural sac closer to L7-S1 in cats
What are contraindications of epidurals?
sepsis
coaguopathy
local infection at site
lumbosacral fractures or dislocations
uncorrcted hypovolemia
What are complications of epidurals?
injection into vertebral vein
hypoventilation
apnea
hypotension