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35 Cards in this Set
- Front
- Back
What are general considerations of local anesthetics?
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-use sterile solution and injection equipment
-always aspirate before injecting -do not inject into infected and inflamed areas |
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What are local anesthetics?
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tertiary amines connected to a aromatic ring
can be aminoesters - procaine can be aminoamindes - lidocaine |
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How are local anesthetics metabolised?
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enzymatic hydrolysis is the primary metabolic pathway
aminoesters hydrolyzed by plasma cholinesterases aminoamides undergo N dealkylation and hydrolysis in hepatic ER |
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What are the onset of action and duration of lidocaine, mepivicaine and bupivicaine?
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lidocaine 3-5 minutes: 1-2 hours
mepivicaine 5-10 minutes: 1.5- 3 hrs Bupivacaine 20-30 minutes: 4-6 hours |
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What is the mechanism of action for local anesthetics?
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inhibit voltage gated sodium channels
block activation of channel and prevent depolarization of cell membrane can be in ionized form - water soluble unionized form - free base and lipid soluble |
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What are adverse effects of local anesthetics?
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-systemic toxiciity
-direct damage to tissues-neurotoxic and myotoxic -allergic reactions -methemoglobinemia benzocaine (cats) |
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What are the signs of CNS toxicity due to local anesthesia?
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muscle twitching and convulsions
unnconciousness coma respiratory arrest |
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What are the signs of cardiovascular toxicity from local anesthetics?
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blockade of sodium channels in purkinkinje fibers and myocardium depresses electrophysiologic and mechanical function of the heart
sinus bradycardia and sinus arrest toxic doses causes vasodilation and hypotension bupivacaine is sepecially cardiotoxic never give bupivacaine IV |
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What local anesthetic should you never give IV?
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bupivicaine
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how do you treat systemic toxicity due to local anesthetics?
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support ventilation and control convulsions
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Where do you apply topical anesthesia, where is it effective?
less effective? |
applied to skin or mucous membranes
very effective on mucous membranes of eyes, nose and mouth less effective penetration of intact skin |
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Where do you apply infiltration anesthesia?
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subcutaneous injection of small volumes of local anesthetics into tissues
diffusion into surrounding tissues anesthetizing nerve fibers and endings incisional line block (linea alba) inverted L block soaker catheters - intermittant injections |
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What are peripheral nerve blocks?
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infection in the immediate vicinity of individual peripheral nerves or nerve plexus
used for cranial nerves, cervical and thoracic nerves lumbar and sacral nerves |
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What is an infraorbital nerve block used for?
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upper dental arcade, upper lip, nose, dorsal aspect of nasal cavity soft and hard palates
used for extraction of canines, incisors and premolars |
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What is a maxillary nerve block used for?
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ipsilateral upper dental arcade, maxilla
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What is a mandibular nerve block used for?
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ipsilateral incisors, canine tooth, premolars, skin and mucosa of the chin and lower lip
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What is a mental nerve block used for?
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rostral mandible, ipsilateral canine and incisors
middle mental foramen, ventral to the lower first and second premolars |
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What are examples of cervical and thoracic nerve blocks?
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brachial plexus block
forelimb nerve block forefoot block intercostal nerve block |
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Where are the brachial plexus blocks?
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C6,C7,C8 and T1
indicated for surgeries or injuries distral to mid diaphysis of humerus |
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What is a nerve stimulator?
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a current applied to the needle as it is inserted into a patient
the closer the needle is to the nerve the less current is needed to stimulate the nerve the principle of a nerve stimulate can be used to locate any nerve not just the brachial plexus |
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What are the uses of forelimb blocks?
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anesthesia of front leg distal to elbow joint-radial , ulnar and metacarpal fractures
four point block median, ulnar, musculocutaneous nerves radial nerve |
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What are the uses of a foot block?
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provides anesthesia distal to carpus common for a declaw
insert needle on dorsomedial aspect of carpus just proximal to joint -median nerve and palmar and dorsal cutaneous branches of ulnar |
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What are the uses of lumbar and sarcal nerve blocks?
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anesthesia of hind leg distal to hip, saphenous, common peroneal and tibial nerve block
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What is the saphenous nerve and what does it do?
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saphenous = branch of femoral nerve that is sensory to medial surface of the thigh, stifle and lower leg
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What does the common peroneal nerve do?
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branch of the sciatic nerve
sensory to the dorsal aspect of lower leg identify the fibula and inject dorsal and posterior to head of fibula |
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What does the tibial nerve do?
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branch of sciatic nerve
sensory to caudal aspect of lower leg Id medial and lateral heads of the gastrocnemius and inject in between |
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What are indications for hindlimb nerve blocks?
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procedures from stifle distally (including stifle)
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What are indications of an infraorbital nerve block in large animals?
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anesthesia of upper lip and nose for suturingnasal laceration
placement of a nose ring in cattle |
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What are indications of a auriculopapebral block in large animals?
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used in horses and cattle for examination and treatment of eye
blockade of auriculopalpebral nerve (motor) akinesia of eyelids |
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What are the indications of the supraorbital nerve block?
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sensation to upper eyelid
nerve emerges from supraorbital foramen |
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What are the indications for peterson and retrobulbar blocks?
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enucleation of eyeball, removal of tumors from eye and eyelids
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What are the indications for a caudal epidural?
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for surgical procedures involving tail, perineum, anus, rectum, vulva, prepuce and skin of the scrotum
-injection of small volume of LA into epidural space at either sacrococcygeal or first intercoccygeal space |
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What are the indications for cranial epidurals?
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use lidocaine or bupivacaine
analgesia as far as T5 in dogs dural sac closer to L7-S1 in cats |
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What are contraindications of epidurals?
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sepsis
coaguopathy local infection at site lumbosacral fractures or dislocations uncorrcted hypovolemia |
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What are complications of epidurals?
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injection into vertebral vein
hypoventilation apnea hypotension |