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30 Cards in this Set

  • Front
  • Back
What type of agent is used most often for premedications?
How about induction?
IV
IV or inhalants
Where do IV meds get delivered first?
What inhibits a drug from leaving the vascular space?
Blood -> vessel rich group - > muscle -> fat

-protein binding
-ionization
-pH
What makes a drug easier to cross the BBB?
lipid soluble
small molecular weight
Blood blow
What are the major barbiturates?
Phenobatbital (12mins onset)
Pentobarbitol (30 sec onset)
Thiopental (15 sec onset)
Is phenobarbital used for general anesthesia?
no it is used for seizures
duration of action is 6-12 hours
What are the CNS effects of barbiturates?
Depression
GABA receptors
no analgesia

causes increased heart rate and decreased blood pressure
What does induction and arousal from anesthesia depend mostly on?
redistribution
Ketamine and tiletamine are examples of what type of anesthetic agent?
What "tone" does it increase? What must therefore be giving with it?
Dissociative
Sympathetic tone
Muscle relaxant
Does ketamine provide analgesia? What reflexes are intact?
Yes
Palpebral, laryngeal, swallowing, slight nystagmus
What are counterindications of ketamine?
1) Brain disorders, ex. seizures
2) Glaucoma
3) Cats with kidney disfunction
What is the only induction imidazole derivative?
Etomidate

the are no cardiovascular or respiratory effects

keep away from light
What kind of drug is saffan?
What animal can't it be used?
Why?
Steroid
Dogs
Histamine release
What is alfaxan missing that's in saffan?
Is induction and recovery slow or rapid?
Is there respiratory depression? How given?
Alfadolone
Rapid
Very little
IV or IM
What type of drug is propofol?
How long after opening must you discard it?
Can you refridgerate this drug?
Phenol derivative
6 hours
No
What are adverse effects of propofol?
cardiovascular depression
respiratory depression
pain at injection site
Where is propofol metabolized?
liver
lungs
kidney
blood
Out of Propofol, Alfaxalone, ketamine or theiobromide, what increase sympathetic tone and provides analgesia?
ketamine
What induction agent is best used in patients with liver disease?
propofol
What drug is contraindicated in a patient with kidney disease?
ketamine
What drug is most likely to cause post induction apnea?
propofol
What is the only induction imidazole derivative?
Etomidate

the are no cardiovascular or respiratory effects

keep away from light
What kind of drug is saffan?
What animal can't it be used?
Why?
Steroid
Dogs
Histamine release
What is alfaxan missing that's in saffan?
Is induction and recovery slow or rapid?
Is there respiratory depression? How given?
Alfadolone
Rapid
Very little
IV or IM
What type of drug is propofol?
How long after opening must you discard it?
Can you refridgerate this drug?
Phenol derivative
6 hours
No
What are adverse effects of propofol?
cardiovascular depression
respiratory depression
pain at injection site
Where is propofol metabolized?
liver
lungs
kidney
blood
Out of Propofol, Alfaxalone, ketamine or theiobromide, what increase sympathetic tone and provides analgesia?
ketamine
What induction agent is best used in patients with liver disease?
propofol
What drug is contraindicated in a patient with kidney disease?
ketamine
What drug is most likely to cause post induction apnea?
propofol