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27 Cards in this Set

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What are the three stages of wound healing?

Inflammatory phase


Proliferation phase


Maturation phase



What takes place during the inflammation phase?

Vasoconstriction, platelet aggregation




Lasts 3-5 days after wound (or longer, if the wound is more severe)

What takes place during the proliferation phase?

Seen 2 weeks after injury




Epithelization- basal epithelium breaks off and produces more epithelium *no hair brough




Angiogenesis




Fibroplasia- ECM, collagen, elastin formation (granulation tissue placed, 7-10 days)

What happens during the maturation phase?

Contraction of the wound, happens 7-9 days after wound




Scar is formed, but will always be 15-20% weaker than the original skin

What are some management factors that interfere with healing?

*Tension, motion, pressure, inadequate debridement, devitalized tissue (eschar), dessication, maceration




(dessication- gets too dry, masseration- too wet)

Define eschar

Dead skin, often associated with burns




Ideal medium for bacterial growth and impedes wound healing

What host factors can interfere with wound management?

Protein deficiency, anemia, uremia, cushing's, addison's, diabetes, vitamine A,C, and E deficiency, corticosteroid medication, chemotherapy, sepsis and old age

What local wound factors can interfere with wound healing?

Oxygen tension, temperature, radiation, neoplasia, infection, foreign body, devitalized tissue, eschar

What are the stages of wound management?

Cleanse


Debride


Lavage- with 0.05% chlorhexidine, 0.1-1.0% povodine-iodine (Inactivated with organic materials), hyperchlorous solutions


Bandage




*don't use hydrogen peroxide for open wound

What are the different options for the contact layer of a bandage?

Wet to dry bandage- causes debridement when removed


Negative pressure- provides suction and faster granulation


Alignates- made from seaweed, forms a gel and then is removed in 3 days

When a wound is in it's proliferation phase, what can you use to as a contact layer in a bandage?

Hydrogels- moist wound environment for granulation




Hydrocolloids- insoluble gel that retains fluid and promotes epithelization. Used for superficial burns




Petroleum impregnated- provides contraction, reduces epithelization

What situations are antibiotics indicated in wound management?

For extensively deep trauma


For contaminated wounds that had to be closed (with a drain)

What situations would make an equine case an emergency?

Airway/breathing obstructed, severe hemorrhage, any clinical signs associated with a surgical lesion (sepsis, dystocia, pain, trauma), urinary obstruction

What is the definition of celiotomy?




What are the categories of?

Surgical incision into the abdominal wall (usually the same as laparotomy)




Treatment- to remove foreign debris


Diagnostic- mass biopsy


Anaphylactic- spay


Elective

What is different about the linea alba in cats?

The linea alba is wider caudally and it is separate from the subcutaneous tissues so you can move around the subcutaneous tissues to find the linea alba (this is not the same case in dogs)




*linea alba is always widest at the umbilicus

What extra precautions need to be taken when making an abdominal incision in the preputial area of a male dog?

Curve the incision laterally around the prepuce




*will have to ligate the preputial vein

What type of suture and suture pattern would you use to close a celiotomy?

Prolonged absorbable/non-absorbable suture




simple interrupted or continuous




*with 6-8 extra throws at the end if you do the continuous pattern

What are the holding layers that you want to incorporate when you close a celiotomy? What layers don't you want to include?

Yes- the external rectus sheath and linea alba




No- the viscera/omentum or any subcutaneous tissue

How do you want to close the subcutaneous layers after you have a holding layer established?




The skin?

SQ- use 3 or 4-0 absorbable suture and a simple cutaneous or buried interrupted pattern




Skin-


Subcuticular, use 3 or 4-0 absorbable


Subcutaneous or cruciate suture, use a 4-0 nonabsorbable suture


*lg. animals are usually closed with ford-interlocking, horizontal mattress or staples

Define gossybipoma. how can you prevent it?

Gossybipoma- a retained surgical sponge




Count them in/out, don't leave in abdomen (always in hand/with forceps), use radio-opaque gauze

When bacteria is present in the abdomen, what is the immune reaction?




What types of things in the stomach make the inflammation worse?

Vasodilation, fibrin formation in order to try to wall off the infection, ileus and rigidity of the intestines




Bile salts, gastric mucous, hemoglobin, barium, increased fluid all make the inflammation worse

What are the ways you classify peritonitis?

primary- from microbes outside the abdomen, usually monomicrobial


Secondary- perforation in intestinal wall , usually polymicrobial - 25% mortality due to not seen until clinical signs already seen


Aseptic- mechanical, foreign body, chemical, parasitic

In chemical peritonitis, what fluids are most irritating? Less irritating?

Most- gastric fluids and pancreatic enzymes




Least irritating- sterile urine and bile

How do you diagnose a case of peritonitis?

PE, imaging, fluid analysis (cytology, lactate, glucose)




*fluid analysis after abdominocentesis is the best tool- do both an aerobic and anaerobic culture

How do you use blood-fluid and peritoneal lactate to diagnose a case of septic peritonitis?

Can only be used in dogs*




Blood-fluid lactate indicator with >2.0mmol/L




Peritoneal lactate indicator with >2.5mmol/L

How do you diagnose uroperitoneum?

Fluid analysis reveals:


Fluid:serum creatinine >2.4:1, potassium >1.4:1




Culture


Contrast imaging

How do you initially start treating a case of septic peritonitis?

Source control, damage control, fluid therapy, drainage, antibiotics




Antibiotics- start emperically then culture-based. Use cephalosporin/ampicillin, aminoglycoside, fluoroquinolone (if no resistance) or metronidazole