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11 Cards in this Set
- Front
- Back
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Clinical features of anemia?
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-easily fatigue, tiredness, SOB
-pallor -decr. appetite -lightheadedness -incr. C.O. (compensatory) |
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Common to ALL anemias?
SaO2? PaO2? O2-content? |
SaO2 = nml
PaO2 = nml O2-content = LOW |
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What tests are used to diagnose Anemia?
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-Complete Blood Count (CBC)
-Periph Blood Smear (PBF) -Bone Marrow exam (w/ Prussian Blue) -Iron studies |
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What typical Iron studies are ordered?
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-serum Iron levels
-serum ferritin levels -Total Iron Binding Capacity (TIBC) -% Iron saturation |
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How long does it take to restore serum RBC to normal levels?
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5-7 days
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How long does a reticulocyte circulate in the blood till it matures to a mature RBC?
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1-2 days
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What is the avg life span of a mature RBC in circulation?
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120 days
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What are some features of anemia d/t
ACUTE Blood Loss? |
-immed hemodilution (normocytic normochromic)
-incr Leukocytosis (early) -incr EPO -reticulocytosis (after 5-7 days) -reticulocytes = polychromatic macrocytes -accompanied Thrombocytosis |
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What are some causes of anemia d/t CHRONIC BLOOS LOSS?
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GI Tract Lesions;
-ulcers, neoplasms, Meckels Divert, PUD, worms GYN disturbances; -menorrhagia, leiomyomas |
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What is a typical cause resulting in Anemia d/t Acute Blood Loss?
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Trauma
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Heriditary Spherocytosis (presents as a Chronic HA)
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• AD
• Ankyrin = most common defect • Spherocytes destroyed in spleen (splenomegaly) = Extravascular hemolysis • Unconjugated bilirubin Jaundice • Aplastic crisis • Confirm Dx: Osmotic fragility test |
