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35 Cards in this Set

  • Front
  • Back

Classes of seizures

partial (focal, local)


generalized


status

Simple partial sz

Partial


common with cerebral lesions


no loss of consciousness


short


motor symptoms start in one part and spread


paresthesias


flashing lights


vocalizations


hallucinations

Complex partial seizure

Partial


Simple partial seizure followed by impaired level of consciousness


May have aura, staring, automatisms



Partial sezures

Simple partial (no LOC)


Complex partial (altered LOC)

Generalized seizures

Absence


Tonic-clonic

Absence

Generalized




Sudden arrest of motor activity with blank stare


The whole body

Tonic-clonic sz

Generalized




Aura


tonic contractions (repetitive involuntary contractions of muscle)


loss of consciousness


clonic contractions (sustained)


incontinence


postictal period



Status epilepticus

series of tonic-clonic sezures lasting >10 min


may occur when awake or asleep


doesn't regain consciousness between seizures

Most important test in determining seizure classification

EEG



CT head

indicated for new onset seizures

Meds for acute seizures

benzos:


diazepam


lorazepam


phenytoin


phosphyenytoin (pro drug of dilantin)


phenobarb


barbitruates

Sz maintenance

carbamazepine


phenytoin


phenobarb


valproic


primodone


clonazepam




never discontinue abruptly, always taper

Parkinson's disease patho

insufficient dopamine

Parkinson's main symptoms

tremmor - slow, most conspicuous at rest, inhanced by stress




rigidity




bradykinesia - slow

Other parkinson's symptoms

wooden facies


imparied swallowing


drooling


decreased blinking


Myerson's sign

Myerson's sign

Parkinson's disease




repetitive tapping over the bridge of the nose produces a sustained blink response

Meds for PD

dopamine


anticholinergics

Dopamine meds for PD

Manage Bradykinesia




carbi-Levo


amantadine


pramipexole


ropinorole



Anticholinergics in PD

allevieate tremmor and rigidity




Benztropine (cogentin)


Trihexyphenidyl (artane)

myesthenia gravis patho

reduction of the number of acetylcholine receptor sites at the neuromuscular junction

Myesthenia gravis ss

weakness typically worse after exercise, better after rest




Ptosis


diplopia


dysarthria


dysphagia


extremity weakness


fatigue


respiratory difficulty




eyes+ other stuff



Ptosis

droopy eyelid

Sensory and DTR in myesthenia

NORMAL

Myesthenia gravis labs

antibodies to ACh receptors (AChR-ab)


Edrophonium test (to differentiate a myasthenic v cholinergic crisis)



Myesthenia management

Anticholinesteras drugs


pyridostigmine


bromide


immunosuppressives


plasmapheresis


vent support during crisis

Multiple sclerosis

Autoimmune




Weakness


numbness (sensory!)


loss of coordination


vision


speech


bladder




Motor + sensory





MS patho

immune system attacks myelin

MS ss

weakness, numbness, tingling, may progress in all limbs


spastic paraparesis


diplopia


disequilibrium


urinary


optic atrophy


nystagmus

MS diagnostic

Never based on labs alone




elevated CSF IgG




MRI

MS management

steroids hasten recovery from acute relapses, but no effect on long term




antispasmodics


interferons


immunosuppressive


plamapheresis

Bell's palse

CN VII (facial)


paralysis - abrupt onset


pain about the eye and weakness


Unable to move forehead


ipsilateral resrtiction of eye closure



forehead movement

Stroke - can move forehead of affected side


Bell's palsy - can't move forhead

Bell's palsy tx

prednisone


acyclovir


eye gtt



Trigeminal neuralgia

CN V


Stabbing, electric-shock



Trigeminal tx

antiseizure durgs - carbamazepine


muscle relaxants


tricyclics