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468 Cards in this Set

  • Front
  • Back

Purpose of this system is to facilitate exchange of respiratory gases between blood & atmosphere

Pulmonary system

Membrane walls of capillary and alveolus are made kf

Simple squamous epithelium

Thinnest barrier that can be constructed by human tissue

Simple squamous epithelium

Essential functions of lung

Ventilation and gas exchange

Movement of air into and out of deep structure of lung (where alveoli are) by expanding and contracting thoracic cavity

Ventilation

Air flowing in and out through airways that connect alveoli to atmosphere, takes place through alveolar capillary interface

Gas exchange

Bulk of gas transport accomplished by _____ through biochemical interactions of gases with hemoglobin protein contained w/in rbc

RBC

Enwrap lungs and line inner surfaces of thoracic cavity

Pleural membranes

Nasopharynx and oropharynx combine at their posterior extreme and Down into throat as the...

Pharynx


(Laryngopharynx)

Ridges on Roof of nasal cavity direct air along roof of cavity where it comes in contact with olfactory epithelium

Nasal turbinates

Muscular cartilaginous flap Protects food from entering airway

Epiglottis

Forms the Adams apple

Thyroid cartilage

Housed within thyroid cartilage, contains vocal cords

Larynx

Lungs are divided into large regions called

Lobes

Number of lobes in R lung

3

# of lobes in L lung

2

Lobes are further divided into 10_____ in each lung

Segments

Largest of airways in thoracic cavity, splits into 2 at midpoint of chest forming R & L mainstream bronchi, carrying air to each lung

Trachea

Through this receptor sympathetic input causes airways to dilate during stress allowing greater ventilation

B2

Through this receptor parasympathetic Activity causes airway constriction enhancing airways ability to clean itself

M3

Smooth muscle cell expresses which two receptors

B2


M3

Teaches becomes bronchioles when

Cartilage disappears and becomes smooth muscle

Epithelium in trachea and bronchi

Pseudostratified columnar

Epithelium in alveoli

Single layer of squamous

Epithelium in bronchiole

Cuboidal

3 types of cells present in alveoli

Type 1


Type II


Type III

Tendency to recoil, resists being stretched

Elastance

Tendency to accommodate being stretched, opposite of elastance

Compliance

Squamous epithelium alveolar cells forms alveolar walls

Type 1

Glandular epithelium alveolar cells secrete surfactant

Type II

Macrophage (WBC) alveolar cells, resident immune cells of lung

type III

Pressure 4( surface tension) divided by radius of chamber

Law of Laplace

Phospholipid molecule interspersed between water molecules on alveoli, causes surface tension to vary with size, prevents alveoli from collapsing, secreted by type II cells

Surfactant

Pathological condition in which type II cells don't produce enough surfactant , causing alveoli to collapse

Atelectasis

Gas stops moving by bulk flow and finishes journey by molecular motion at what point

End of bronchioles


(Terminal bronchioles)

In normal restful breathing inhale ____ & exhale _____

Actively, passively

Primary muscle of restful breathing

Diaphragm

Three body fluid compartments

ICF


Interstitial


Plasma

Percent of ICF and ECF in body water

ICF : 66%


ECF: 33%

Three body fluid compartments

ICF


Interstitial


Plasma

Two subdivisions of ECF and their percentagss

Interstitial: 25%


Plasma: 8%

Ions can't move across cell membrane they are either inside/ outside of cell , if they are outside they can move between ______ & ______

Interstitium and plasma

Ions can't move across cell membrane they are either inside/ outside of cell , if they are outside they can move between ______ & ______

Interstitium and plasma

When Fluid accumulates in interstitial space

Edema, third spacing fluid

Indented area of kidney

Hilum

Three tubes connected to hilum

Renal artery


Renal vein


Ureter

Indented area of kidney

Hilum

Delivers blood supply from abdominal aorta

Renal artery

Indented area of kidney

Hilum

Three tubes connected to hilum

Renal artery


Renal vein


Ureter

Delivers blood supply from abdominal aorta

Renal artery

Drains blood back to vena cava

Renal vein

Three tubes connected to hilum

Renal artery


Renal vein


Ureter

Delivers blood supply from abdominal aorta

Renal artery

Drains blood back to vena cava

Renal vein

Drains urine from kidney into bladder

Ureter

Indented area of kidney

Hilum

Three tubes connected to hilum

Renal artery


Renal vein


Ureter

Delivers blood supply from abdominal aorta

Renal artery

Drains blood back to vena cava

Renal vein

Drains urine from kidney into bladder

Ureter

Located in pelvic cavity and stores finished urine until urination

Urinary bladder

Indented area of kidney

Hilum

Three tubes connected to hilum

Renal artery


Renal vein


Ureter

Delivers blood supply from abdominal aorta

Renal artery

Drains blood back to vena cava

Renal vein

Drains urine from kidney into bladder

Ureter

Located in pelvic cavity and stores finished urine until urination

Urinary bladder

Two functional layers of kidney

Cortex medulla

Indented area of kidney

Hilum

Three tubes connected to hilum

Renal artery


Renal vein


Ureter

Delivers blood supply from abdominal aorta

Renal artery

Drains blood back to vena cava

Renal vein

Drains urine from kidney into bladder

Ureter

Located in pelvic cavity and stores finished urine until urination

Urinary bladder

Two functional layers of kidney

Cortex medulla

Functional layer of kidney , outer layer, continuous 3d band of tissue

Cortex

Indented area of kidney

Hilum

Three tubes connected to hilum

Renal artery


Renal vein


Ureter

Delivers blood supply from abdominal aorta

Renal artery

Drains blood back to vena cava

Renal vein

Drains urine from kidney into bladder

Ureter

Located in pelvic cavity and stores finished urine until urination

Urinary bladder

Two functional layers of kidney

Cortex medulla

Functional layer of kidney , outer layer, continuous 3d band of tissue

Cortex

Functional layer of kidney, inner layer, broken up into small segments

Medulla

Indented area of kidney

Hilum

Three tubes connected to hilum

Renal artery


Renal vein


Ureter

Delivers blood supply from abdominal aorta

Renal artery

Drains blood back to vena cava

Renal vein

Drains urine from kidney into bladder

Ureter

Located in pelvic cavity and stores finished urine until urination

Urinary bladder

Two functional layers of kidney

Cortex medulla

Functional layer of kidney , outer layer, continuous 3d band of tissue

Cortex

Functional layer of kidney, inner layer, broken up into small segments

Medulla

Innermost area of kidney where urine collects and drained by ureter

Renal pelvis

Indented area of kidney

Hilum

Entire outer surface of kidney is covered by fibrous sheath called

Capsule

Three tubes connected to hilum

Renal artery


Renal vein


Ureter

Delivers blood supply from abdominal aorta

Renal artery

Drains blood back to vena cava

Renal vein

Drains urine from kidney into bladder

Ureter

Located in pelvic cavity and stores finished urine until urination

Urinary bladder

Two functional layers of kidney

Cortex medulla

Functional layer of kidney , outer layer, continuous 3d band of tissue

Cortex

Innermost area of kidney where urine collects and drained by ureter where all calyx come together

Renal pelvis

Innermost area of kidney where urine collects and drained by ureter

Renal pelvis

Any loss that cannot be collected/ measured (everything except urine)

Insensible loss

Functional unit of the kidney, able to carry out complete job of forming urine, dead ended tube with open draining into calyx

Nephron

First funnel to catch urine many small nephrons drain here

Renal pyramid

First funnel to catch urine many small nephrons drain here

Renal pyramid

Exit of renal pyramid

Papilla

First funnel to catch urine many small nephrons drain here

Renal pyramid

Exit of renal pyramid

Papilla

Tube connects to pyramid to catch draining urine

Calyx

Tiny branches of renal arteries that lead into each nephron (goes into bowmans capsule)

Afferent arteriole

Tiny branches of renal arteries that lead into each nephron (goes into bowmans capsule)

Afferent arteriole

Capsule contains glomerulus and catches water electrolytes and waste products that are being filtered out by glomerulus then drains to proximal tubules

Bowmans capsule

Tiny branches of renal arteries that lead into each nephron (goes into bowmans capsule)

Afferent arteriole

All renal corpuscles lie in ___ region of kidney

Cortex

Three processes by which urine is formed

Filtration


Reapsorption


Secretion

Where does filtration occur

Glomerulus

Where does reabsorption occur

All along tubule

Where does secretion occur

Distal tube

Antiport function linked to more na+ reabsorption

Secretion

Capsule contains glomerulus and catches water electrolytes and waste products that are being filtered out by glomerulus then drains to proximal tubules

Bowmans capsule

Network of tiny capillaries that allow blood to be filtered with processes of diffusion and osmosis, waste products electrolytes and water start to leave the blood stream and enter bowmans capsule

Glomerulus

Bowmans capsule and glomerulus together as a single unit

Renal corpuscles

Flows into DCT , loop shape where diffusion takes place

Loop of henle

Concentrating out urine by resorbing some electrolytes/ h2o (diffusion/osmosis) items body wants to keep leave proximal tube and enter interstitial fluid. as electrolytes leave water follows along.

PCT


Proximal convoluted tubule

Continues the process of reabsorption of electrolytes (na+&h20) if body needs to retain water then tubule continues to re absorb h2o which concentrates urine further and causes Urine to look darker. If body needs to get rid of h2o distal tubule will allow more water to stay in urine

DCT


distal convoluted tubule

Final step of urine concentration carries concentrated urine to renal pyramid

Collecting duct

When electrolytes/h20 leave proximal/distal tube & enter interstitial fluid, they eventually pass into system of these capillaries and return to main blood stream

Peritubular capillaries

Nephron tubule composed of simple epithelium membrane surrounding _______

Elongated lumen

Tiny branches of renal arteries that lead into each nephron (goes into bowmans capsule)

Afferent arteriole

All renal corpuscles lie in ___ region of kidney

Cortex

Three processes by which urine is formed

Filtration


Reapsorption


Secretion

Where does filtration occur

Glomerulus

Where does reabsorption occur

All along tubule

Where does secretion occur

Distal tube

Antiport function linked to more na+ reabsorption

Secretion

All urine formation is driven by ____ ________ everything other than sodium is moving by cotransport antiport electrical gradient or osmosis

Na+ reabsorption

Capsule contains glomerulus and catches water electrolytes and waste products that are being filtered out by glomerulus then drains to proximal tubules

Bowmans capsule

Network of tiny capillaries that allow blood to be filtered with processes of diffusion and osmosis, waste products electrolytes and water start to leave the blood stream and enter bowmans capsule

Glomerulus

Bowmans capsule and glomerulus together as a single unit

Renal corpuscles

Flows into DCT , loop shape where diffusion takes place

Loop of henle

Concentrating out urine by resorbing some electrolytes/ h2o (diffusion/osmosis) items body wants to keep leave proximal tube and enter interstitial fluid. as electrolytes leave water follows along.

PCT


Proximal convoluted tubule

Continues the process of reabsorption of electrolytes (na+&h20) if body needs to retain water then tubule continues to re absorb h2o which concentrates urine further and causes Urine to look darker. If body needs to get rid of h2o distal tubule will allow more water to stay in urine

DCT


distal convoluted tubule

Final step of urine concentration carries concentrated urine to renal pyramid

Collecting duct

When electrolytes/h20 leave proximal/distal tube & enter interstitial fluid, they eventually pass into system of these capillaries and return to main blood stream

Peritubular capillaries

Nephron tubule composed of simple epithelium membrane surrounding _______

Elongated lumen

Checks how well kidneys are working, estimates how much blood passes through glomeruli, rate at which plasma fluid is being pushed through glomerulus sleeve into bowmans space

Glomerular filtration rate (GFR)

Checks how well kidneys are working, estimates how much blood passes through glomeruli, rate at which plasma fluid is being pushed through glomerulus sleeve into bowmans space

Glomerular filtration rate (GFR)

Three factors used to calculate GFR

Concentration, rate urine was produced in 24hrs, concentration of the same substance in plasma (serum)

Checks how well kidneys are working, estimates how much blood passes through glomeruli, rate at which plasma fluid is being pushed through glomerulus sleeve into bowmans space

Glomerular filtration rate (GFR)

Three factors used to calculate GFR

Concentration, rate urine was produced in 24hrs, concentration of the same substance in plasma (serum)

GFR is affected by ..

Anything decreases amount of blood flowing through kidney (hypertension,heartfailure, atherosclerosis)

Affected by pressures (hydrostatic,osmotic,microcircation) and Fick factors (area/permeability)

GFR

Affected by pressures (hydrostatic,osmotic,microcircation) and Fick factors (area/permeability)

GFR

Only factor of GFR kidney can control

Hydrostatic pressure by operating afferent & efferent arterioles that control pressure on glomerulus

Steroid hormone increases calcium reabsorption

Vitamin D

Steroid hormone increases calcium reabsorption

Vitamin D

Peptide hormone decreases phosphate reabsorption

PTH

Steroid hormone increases calcium reabsorption

Vitamin D

Peptide hormone decreases phosphate reabsorption

PTH

Peptide hormone increases water reabsorption

ADH

Rate of filtration affected by

Area


Permeability


P gradient (hydrostatic)


P gradient (osmotic)

Rate of filtration affected by

Area


Permeability


P gradient (hydrostatic)


P gradient (osmotic)

Rate of filtration influenced by these Factors inside kidney

Integrity of glomerulus


Control of afferent/efferent arterioles

Rate of filtration affected by

Area


Permeability


P gradient (hydrostatic)


P gradient (osmotic)

Rate of filtration influenced by these Factors inside kidney

Integrity of glomerulus


Control of afferent/efferent arterioles

Rate of filtration influenced by these factors outside kidney

Systemic BP


Serum protein content

Rate at which a substance is removed from the blood by the kidneys is called its

Clearance

Rate at which a substance is removed from the blood by the kidneys is called its

Clearance

Plasma is the remainder of blood volume if we subtract HCT so u can also estimate renal blood flow by this formula

Rpf*100


___________


100 * HCT

Only subject to filtration but is not reabsorbed or secreted

Creatinine

Only subject to filtration but is not reabsorbed or secreted

Creatinine

GFR is equivalent to

RPF


Renal plasma flow rate

What kind of epithelium is on descending loop of henle

Simple squamous

What kind of epithelium is on descending loop of henle

Simple squamous

What kind of epithelium is on ascending loop of henle

Columnar

What kind of epithelium is on descending loop of henle

Simple squamous

What kind of epithelium is on ascending loop of henle

Columnar

Descending loop of Henley is called ____ limb

Thin

What kind of epithelium is on descending loop of henle

Simple squamous

What kind of epithelium is on ascending loop of henle

Columnar

Descending loop of Henley is called ____ limb

Thin

Ascending loop of henle is called ___\ limb

Thick

What kind of epithelium is on descending loop of henle

Simple squamous

What kind of epithelium is on ascending loop of henle

Columnar

Descending loop of Henley is called ____ limb

Thin

Ascending loop of henle is called ___\ limb

Thick

Portion of loop of henle very water permeable

Thin descending limb

What kind of epithelium is on descending loop of henle

Simple squamous

What kind of epithelium is on ascending loop of henle

Columnar

Descending loop of Henley is called ____ limb

Thin

Ascending loop of henle is called ___\ limb

Thick

Portion of loop of henle very water permeable

Thin descending limb

Portion of loop of henle has cells full of enzymes, pumps and other protein machinery, performs vigorous active transport that results in large amount of solute reabsorption (impermeable to water)

Thick ascending loop

When filtrate is initially formed it is essentially _____ with ____

Isotonic , plasma

Senses any increase in sodium chloride in distal tubule of kidney and secreted locally active vasopressor (paracrine) which acts on afferent arterioles to decrease GFR

Macula densa

Molecule reabsorbed by active transport (only thing actively transported)

Na+

Molecule reabsorbed by active transport (only thing actively transported)

Na+

Two acids are pulled into tubule cell by cotransport with na+ and flow out the other side by facilitated diffusion

Glucose


Amino acids

Molecule reabsorbed by active transport (only thing actively transported)

Na+

Two acids are pulled into tubule cell by cotransport with na+ and flow out the other side by facilitated diffusion

Glucose


Amino acids

Molecule follows electrical gradient created by na+ reabsorption

Cl-

Molecule reabsorbed by active transport (only thing actively transported)

Na+

Two acids are pulled into tubule cell by cotransport with na+ and flow out the other side by facilitated diffusion

Glucose


Amino acids

Molecule follows electrical gradient created by na+ reabsorption

Cl-

Molecule follows osmotic gradient created by all those solutes moving out of the urine and into the blood

Water

Molecule reabsorbed by active transport (only thing actively transported)

Na+

Two acids are pulled into tubule cell by cotransport with na+ and flow out the other side by facilitated diffusion

Glucose


Amino acids

Molecule follows electrical gradient created by na+ reabsorption

Cl-

Molecule follows osmotic gradient created by all those solutes moving out of the urine and into the blood

Water

Molecule secreted when aldosterone prompts the tubule cells to make /install luminal k+ channels

K+

Molecule reabsorbed by active transport (only thing actively transported)

Na+

Two acids are pulled into tubule cell by cotransport with na+ and flow out the other side by facilitated diffusion

Glucose


Amino acids

Molecule follows electrical gradient created by na+ reabsorption

Cl-

Molecule follows osmotic gradient created by all those solutes moving out of the urine and into the blood

Water

Molecule secreted when aldosterone prompts the tubule cells to make /install luminal k+ channels

K+

Molecule secreted when systemic ph is low, as acid builds up in the body , the tubule cells convert co2 into acid , secreting the H+ into the tubule and saving the hco3 (bicarbonate ion) helping to buffer more h+ in body

H+

Molecule reabsorbed by active transport (only thing actively transported)

Na+

Two acids are pulled into tubule cell by cotransport with na+ and flow out the other side by facilitated diffusion

Glucose


Amino acids

Molecule follows electrical gradient created by na+ reabsorption

Cl-

Molecule follows osmotic gradient created by all those solutes moving out of the urine and into the blood

Water

Molecule secreted when aldosterone prompts the tubule cells to make /install luminal k+ channels

K+

Molecule secreted when systemic ph is low, as acid builds up in the body , the tubule cells convert co2 into acid , secreting the H+ into the tubule and saving the hco3 (bicarbonate ion) helping to buffer more h+ in body

H+

Secreted when build up of amino groups from using protein as fuel is shuttled into tubule cells as glutamine .. This is then broken down to Nh3, h+, & hco3

Nitrogenous wastes

Molecule reabsorbed by active transport (only thing actively transported)

Na+

Two acids are pulled into tubule cell by cotransport with na+ and flow out the other side by facilitated diffusion

Glucose


Amino acids

Molecule follows electrical gradient created by na+ reabsorption

Cl-

Molecule follows osmotic gradient created by all those solutes moving out of the urine and into the blood

Water

Molecule secreted when aldosterone prompts the tubule cells to make /install luminal k+ channels

K+

Molecule secreted when systemic ph is low, as acid builds up in the body , the tubule cells convert co2 into acid , secreting the H+ into the tubule and saving the hco3 (bicarbonate ion) helping to buffer more h+ in body

H+

Secreted when build up of amino groups from using protein as fuel is shuttled into tubule cells as glutamine .. This is then broken down to Nh3, h+, & hco3

Nitrogenous wastes

Nh3 diffuses in tubule & h+ secreted by antiporting combine in tubule to form the insoluble _____ which is then trapped outside and can't get back in body

Nh4+

Average urine volume per day

1.4 liters

Retrieves large portion of water that still remains in tubule after PCT increasing amount of na+ and water absorbed

Countercurrent mechanism

Controls rate of GFR by sensing how fast filtrate is running through tubule

TGF


Tubuloglomerular feedback

Retrieves large portion of water that still remains in tubule after PCT increasing amount of na+ and water absorbed

Countercurrent mechanism

Controls rate of GFR by sensing how fast filtrate is running through tubule

TGF


Tubuloglomerular feedback

When there is too much na+ filtrate will be running too ___ & GFR will be too. _____

Fast

Retrieves large portion of water that still remains in tubule after PCT increasing amount of na+ and water absorbed

Countercurrent mechanism

Controls rate of GFR by sensing how fast filtrate is running through tubule

TGF


Tubuloglomerular feedback

When there is too much na+ filtrate will be running too ___ & GFR will be too. _____

Fast

If na+ is too low filtrate will be flowing too ____ and GFR will be too _____

Slow

Retrieves large portion of water that still remains in tubule after PCT increasing amount of na+ and water absorbed

Countercurrent mechanism

Controls rate of GFR by sensing how fast filtrate is running through tubule

TGF


Tubuloglomerular feedback

When there is too much na+ filtrate will be running too ___ & GFR will be too. _____

Fast

If na+ is too low filtrate will be flowing too ____ and GFR will be too _____

Slow

How does macula densa decrease na+ when there is too much

Drop pressure in glomerulus by dilating efferent arterioles

Retrieves large portion of water that still remains in tubule after PCT increasing amount of na+ and water absorbed

Countercurrent mechanism

Controls rate of GFR by sensing how fast filtrate is running through tubule

TGF


Tubuloglomerular feedback

When there is too much na+ filtrate will be running too ___ & GFR will be too. _____

Fast

If na+ is too low filtrate will be flowing too ____ and GFR will be too _____

Slow

How does macula densa decrease na+ when there is too much

Drop pressure in glomerulus by dilating efferent arterioles

How does macula densa raise na+ when too low

Increase pressure in glomerulus by dilating afferent arteriole & allowing efferent arteriole to constrict

Urine with a lot of water, what we do when over hydrated

Dilute urine

Urine with a lot of water, what we do when over hydrated

Dilute urine

Urine has less water , what we do when dehydrated

Concentrated urine

Urine with a lot of water, what we do when over hydrated

Dilute urine

Urine has less water , what we do when dehydrated

Concentrated urine

Urine is accomplished by not secreting ADH

Dilute urine

Urine with a lot of water, what we do when over hydrated

Dilute urine

Urine has less water , what we do when dehydrated

Concentrated urine

Urine is accomplished by not secreting ADH

Dilute urine

Urine accomplished by secreting ADH which puts in more water channels at distal tube to take back more water

Concentrated urine

Process of urination emptying bladder

Micturition

Micturition is controlled by what type of reflec

Parasympathetic

Micturition is controlled by what type of reflec

Parasympathetic

Micturition can in turn be controlled by conscious neural input from brain called

Cortex

Sphincter subject to conscious neural input from brain

External sphincter

Micturition is controlled by what type of reflec

Parasympathetic

Micturition can in turn be controlled by conscious neural input from brain called

Cortex

Sphincter subject to conscious neural input from brain

External sphincter

Failure of reflex mechanism to empty bladder

Paralytic ileus

Micturition is controlled by what type of reflec

Parasympathetic

Micturition can in turn be controlled by conscious neural input from brain called

Cortex

Sphincter subject to conscious neural input from brain

External sphincter

Failure of reflex mechanism to empty bladder

Paralytic ileus

Sympathetic reflex at bladder only operates during

Orgasm to prevent using urethral tract

Micturition is controlled by what type of reflec

Parasympathetic

Micturition can in turn be controlled by conscious neural input from brain called

Cortex

Sphincter subject to conscious neural input from brain

External sphincter

Failure of reflex mechanism to empty bladder

Paralytic ileus

Sympathetic reflex at bladder only operates during

Orgasm to prevent using urethral tract

The bladder will not back up into kidneys and damage them bc at high volume discomfort will override ______

Brains conscious control to stop It from emptying

Ph Lower than 7.4

Acidosis

Ph Lower than 7.4

Acidosis

Ph higher than 7.4

Alkalosis

Normal hco3- level

24.1

Normal pco2 lecel

40

Ph Lower than 7.4

Acidosis

Ph higher than 7.4

Alkalosis

Normal hco3- level

24.1

Normal pco2 lecel

40

Ph Lower than 7.4

Acidosis

Ph higher than 7.4

Alkalosis

Normal hco3- level

24.1

Normal pco2 lecel

40

This type of acidosis would occur in patient whose pulmonary system healthy and functioning normally

Metabolic acidosis

Ph Lower than 7.4

Acidosis

Ph higher than 7.4

Alkalosis

Normal hco3- level

24.1

Normal pco2 lecel

40

This type of acidosis would occur in patient whose pulmonary system healthy and functioning normally

Metabolic acidosis

Type of acidosis would form person fails to perform adequate ventilation or gas exchange

Respiratory acidosis

Low ph and excess respiratory acid (co2) would cause

Respiratory acidosis

Low ph and excess respiratory acid (co2) would cause

Respiratory acidosis

Examples of this acid imbalance : Brain stem injury, sedation, copd , airway disease

Respiratory Acidosis

Low ph


High pco2 level


Normal to high hco3

Respiratory acidosis

Type of acidosis would cause hyperventilation rapid and onset observable

Metabolic acidosis

Type of acidosis would cause hyperventilation rapid and onset observable

Metabolic acidosis

Cause of LOW ph is excess acid not from c02


Increased h+ production


Loss of hco3


Normal to low pco2

Metabolic acidosis

Acidosis with Excess acid such as cells using lipids for fuel instead of glucose

Metabolic acidosis

May occur when fasting or dieting

Metabolic acidosis

When patient is in this acidosis kidney will attempt to compensate by secreting acid using na+/h+ exchange mechanism

Respiratory acidosis

Two ways patient can become alkalotic

Ph rise above normal


Loses too much acid from system

Two ways patient can become alkalotic

Ph rise above normal


Loses too much acid from system

Example of this alkalosis would be prolonged vomiting/ poisoning

Metabolic alkalosis

Two ways patient can become alkalotic

Ph rise above normal


Loses too much acid from system

Example of this alkalosis would be prolonged vomiting/ poisoning

Metabolic alkalosis

High ph


Normal to high pco2


High hco3-

Metabolic alkalosis

Two ways patient can become alkalotic

Ph rise above normal


Loses too much acid from system

Example of this alkalosis would be prolonged vomiting/ poisoning

Metabolic alkalosis

High ph


Normal to high pco2


High hco3-

Metabolic alkalosis

Alkalosis would cause hypoventilation rapid onset and observable

Metabolic alkalosis

Cause of this alkalosis would be excess bicarb (buffer) & loss of h+ (source in change is metabolic function)

Metabolic alkalosis

Alkalosis occurs when patient breathes too vigorously

Respiratory alkalosis

Alkalosis due to excess co2 loss

Respiratory alkalosis

Alkalosis due to excess co2 loss

Respiratory alkalosis

Example of this alkalosis would be hyperventilation and high altitude

Respiratory alkalosis

Alkalosis due to excess co2 loss

Respiratory alkalosis

Example of this alkalosis would be hyperventilation and high altitude

Respiratory alkalosis

High ph


Low pco2


Low to normal hco3-

Respiratory alkalosis

Serum anion gap


(Na+) - (hco3-) + (cl-)


Increases during

Metabolic acidosis

Kidney detects low bp and releases

Renin

Kidney detects low bp and releases

Renin

Release of renin leads to activation of

Angiotensin

Kidney detects low bp and releases

Renin

Release of renin leads to activation of

Angiotensin

Angiotensin constricts arteries and veins which increase _____, _____,& ______

Preload


SV


Co

Kidney detects low bp and releases

Renin

Release of renin leads to activation of

Angiotensin

Angiotensin constricts arteries and veins which increase _____, _____,& ______

Preload


SV


Co

Angiotensin triggers release of aldosterone which help to raise bp by increasing

Na reabsorption

Two forms of renal failure

Acute and chronic

Two forms of renal failure

Acute and chronic

Presence of inflammation indicating presence of infection. (Protein and blood cells present in urine)

Nephritis

Two forms of renal failure

Acute and chronic

Presence of inflammation indicating presence of infection. (Protein and blood cells present in urine)

Nephritis

See only protein (no blood in urine ) bc cause does not involve inflammation but autoimmune destruction of integrity of glomerulus

Nephrosis

Two forms of renal failure

Acute and chronic

Presence of inflammation indicating presence of infection. (Protein and blood cells present in urine)

Nephritis

See only protein (no blood in urine ) bc cause does not involve inflammation but autoimmune destruction of integrity of glomerulus

Nephrosis

GFR initially goes up and then as disease progresses GFR goes down

Nephrosis

Two forms of renal failure

Acute and chronic

Presence of inflammation indicating presence of infection. (Protein and blood cells present in urine)

Nephritis

See only protein (no blood in urine ) bc cause does not involve inflammation but autoimmune destruction of integrity of glomerulus

Nephrosis

GFR initially goes up and then as disease progresses GFR goes down

Nephrosis

GFR goes down from the beginning

Nephritis

Bladder urethra and ureter are lined with _____ epithelium

Transitional

The total volume of the respiratory system

TLC


Total lung capacity

The total volume of the respiratory system

TLC


Total lung capacity

Maximum volume of ventilation available for the maximum oxygen it demands of the body

Vital capacity

The total volume of the respiratory system

TLC


Total lung capacity

Maximum volume of ventilation available for the maximum oxygen it demands of the body

Vital capacity

Spaces that can never be emptied under normal ventilatory functions (do not completely collapse)

Residual volume

The total volume of the respiratory system

TLC


Total lung capacity

Maximum volume of ventilation available for the maximum oxygen it demands of the body

Vital capacity

Spaces that can never be emptied under normal ventilatory functions (do not completely collapse)

Residual volume

Larger of exp/inspir. Reserves greater lung space that can be inflated using accessory muscle/energy


Active inhale passive exhale

Inspiratory reserve

The total volume of the respiratory system

TLC


Total lung capacity

Maximum volume of ventilation available for the maximum oxygen it demands of the body

Vital capacity

Spaces that can never be emptied under normal ventilatory functions (do not completely collapse)

Residual volume

Larger of exp/inspir. Reserves greater lung space that can be inflated using accessory muscle/energy


Active inhale passive exhale

Inspiratory reserve

Normal person breath at rest using only diaphragm to inflate the base of lungs (midpoint of TLC)

Tidal volume

The total volume of the respiratory system

TLC


Total lung capacity

Maximum volume of ventilation available for the maximum oxygen it demands of the body

Vital capacity

Spaces that can never be emptied under normal ventilatory functions (do not completely collapse)

Residual volume

Larger of exp/inspir. Reserves greater lung space that can be inflated using accessory muscle/energy


Active inhale passive exhale

Inspiratory reserve

Normal person breath at rest using only diaphragm to inflate the base of lungs (midpoint of TLC)

Tidal volume

Active exhale passive inhale


Below resting point, muscles can be used to compress lung

Expiratory reserve

Why does tidal volume occur in middle of breathing range (TLC)

Elastance lowest


Capacitance highest

Air flows into and out of lungs through

Tubular airways

Formula for flow of air

Driving pressure divided by resistance

Atmospheric pressure at sea level

760 mmhg

Factor affected when determining flow of airways

Radius

What type of molecule is surfactant

Phospholipid

Interior of thoracic cage and is lined with thin squamous membrane called

Parietal pleura

Exterior surface of lung is covered with

Visceral pleura

Two pleuras slide back and forth when chest cage expands

Visceral


Parietal

What type of molecule is surfactant

Phospholipid

Interior of thoracic cage and is lined with thin squamous membrane called

Parietal pleura

Exterior surface of lung is covered with

Visceral pleura

Two pleuras slide back and forth when chest cage expands

Visceral


Parietal

Inter pulmonary pressure is equal to atmospheric pressure (760mmhg) ....

At rest between breaths

What type of molecule is surfactant

Phospholipid

Interior of thoracic cage and is lined with thin squamous membrane called

Parietal pleura

Exterior surface of lung is covered with

Visceral pleura

Two pleuras slide back and forth when chest cage expands

Visceral


Parietal

Inter pulmonary pressure is equal to atmospheric pressure (760mmhg) ....

At rest between breaths

At the beginning of a breath as air flows in lung space is enlarged and diaphragm contracts , so intrapulmomary pressure is _____ 760 mmhg

Less than

What type of molecule is surfactant

Phospholipid

Interior of thoracic cage and is lined with thin squamous membrane called

Parietal pleura

Exterior surface of lung is covered with

Visceral pleura

Two pleuras slide back and forth when chest cage expands

Visceral


Parietal

Inter pulmonary pressure is equal to atmospheric pressure (760mmhg) ....

At rest between breaths

At the beginning of a breath as air flows in lung space is enlarged and diaphragm contracts , so intrapulmomary pressure is _____ 760 mmhg

Less than

In the middle of a breath lung pressure equilibrates with atmospheric pressure so pressure = ____ mmhg in the middle of breath

760

What type of molecule is surfactant

Phospholipid

Interior of thoracic cage and is lined with thin squamous membrane called

Parietal pleura

Exterior surface of lung is covered with

Visceral pleura

Two pleuras slide back and forth when chest cage expands

Visceral


Parietal

Inter pulmonary pressure is equal to atmospheric pressure (760mmhg) ....

At rest between breaths

At the beginning of a breath as air flows in lung space is enlarged and diaphragm contracts , so intrapulmomary pressure is _____ 760 mmhg

Less than

In the middle of a breath lung pressure equilibrates with atmospheric pressure so pressure = ____ mmhg in the middle of breath

760

At the end of breath air flows out and lung space is reduced (diaphragm relaxes) so intrapulmomary pressure is _____ that 760mmhg

Greater

Law says a quantity of gas always exerts a pressure

Dalton's law

Law says a quantity of gas always exerts a pressure

Dalton's law

In a mixture of gases the % of each gas in that mixture is equal to the portion of pressure exerted by that gas this is the gas's

Partial pressure Pgas

Law says a quantity of gas always exerts a pressure

Dalton's law

In a mixture of gases the % of each gas in that mixture is equal to the portion of pressure exerted by that gas this is the gas's

Partial pressure Pgas

Total pressure of whole mixture of atmospheric gases at sea level is

760 mmhg

98% of oxygen traveling to tissues in arterial blood is bound to _____ and only 2% remains in ______ state

HGB , dissolved

1/3 of co2 traveling in blood remains in dissolved state and about 2/3 traveling in blood has been converted to ______ bound to _____

Acid, HGB

Law says blood tends to release oxygen as serum ph decreases because hemoglobin has less affinity for binding oxygen in an acidic condition

Bohr effect

Law says blood tends to release oxygen as serum ph decreases because hemoglobin has less affinity for binding oxygen in an acidic condition

Bohr effect

Enables blood to release oxygen at tissues

Bohr effect

Three factors exercised muscle (greatest level of all three Bohr factors)

Warm


Hypercarbic


Acidic

Describes Variables that effect the diffusion of gases across a permeable barrier

Ficks law

Describes Variables that effect the diffusion of gases across a permeable barrier

Ficks law

Areas that are ventilated but do not provide any gas exchange

Deadspace

Describes Variables that effect the diffusion of gases across a permeable barrier

Ficks law

Areas that are ventilated but do not provide any gas exchange

Deadspace

Each Fick factor can be altered in normal physiology or disease except ______

Solubility of the gases

Describes Variables that effect the diffusion of gases across a permeable barrier

Ficks law

Areas that are ventilated but do not provide any gas exchange

Deadspace

Each Fick factor can be altered in normal physiology or disease except ______

Solubility of the gases

Primary controller for ventilatory pattern is a cluster of neurons called

Dorsal respiratory group (DRG)

Neurons in brainstem that respond to decreasing systemic oh (primary controller for adjusting ventilation pattern)

Central chemosensors

Two chemoreceptors

Central peripheral

Two chemoreceptors

Central peripheral

Where are central chemoreceptors located

Brainstem

Two chemoreceptors

Central peripheral

Where are central chemoreceptors located

Brainstem

Where are peripheral chemosensors located

Carotids

Two chemoreceptors

Central peripheral

Where are central chemoreceptors located

Brainstem

Where are peripheral chemosensors located

Carotids

Chemoreceptor that sense ph, stimulates DRG , inhibits MIN

Central chemoreceptor

Two chemoreceptors

Central peripheral

Where are central chemoreceptors located

Brainstem

Where are peripheral chemosensors located

Carotids

Chemoreceptor that sense ph, stimulates DRG , inhibits MIN

Central chemoreceptor

Chemoreceptor that senses Po2, stimulates DRG , inhibits MIN

Peripheral chemoreceptor

Two chemoreceptors

Central peripheral

Where are central chemoreceptors located

Brainstem

Where are peripheral chemosensors located

Carotids

Chemoreceptor that sense ph, stimulates DRG , inhibits MIN

Central chemoreceptor

Chemoreceptor that senses Po2, stimulates DRG , inhibits MIN

Peripheral chemoreceptor

Located in lungs, stretch activated, inhibit DRG, stimulate MIN

Mechanoreceptors

Two gases effecting green house effect

Water vapor


Co2

Exit of renal pyramid

Papilla

Exit of renal pyramid

Papilla

Tube connects to renal pyramid to catch draining urine

Calyx

In upper airways you need ____ to clean out particulate matter that gets into airways

Cilia (mucus)