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191 Cards in this Set
- Front
- Back
Special Senses
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- olfaction, vision, gustation, hearing, equilibrium
- Detected by complex receptors in sense organs |
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Reflex Path for Special Senses (Complex Receptor)
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- Receptor cell receives stimulus
- Changes receptor cell potential - Changes Sensory Neuron Potential - Threshold - Action Potential Sent |
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Olfaction
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Sense of smell
Receptors react to airborne odorants |
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Olfactory Organs
1. Olfactory Epithelium |
- Has receptors w/ cilia lined knobs
- Cilia creates increased surface area network |
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Olfactory Organs
2. Lamina Propria |
- Vessels nerves glands and loose ct
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Olfactory Pathway
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odorants absorbed at cilia and bind receptors -> ap sent to CNS
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Olfactory Discrimination
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- Chemicals activate receptor combos
- CNS interprets smell due to pattern |
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Aging and Olfaction
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age ¯ olfactory sensitivity
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Gustation
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- Sense of taste
Receptors react to dissolved tastants |
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Gustatory Organs
Tongue |
Contains receptor taste buds (tb)
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Gustatory Organs
Filiform Papillae |
- Sharp projections grip food, no tbs
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Gustatory Organs
Fungiform Papillae |
- Rounded projection w/ a few tbs
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Gustatory Organs
Circumvallate Papillae |
Rounded projections w/ increased tbs
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Gustatory Organs
Taste Bud |
gustatory cell (gc) + specialized cells
-gc extends taste hairs (microvilli) thru taste pore |
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Gustatory Pathway
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- Tastants absorbed at microvilli and bind receptors -> ap sent to CNS
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Gustatory Discrimination
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- Chemicals activate receptor combos
CNS interprets taste due to pattern |
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Aging and Gustation
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Increase age decrease gustatory sensitivity
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Vision
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sense of sight involves accessory structures, eyes and photoreceptors
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Accessory Structures
Eyelashes |
Protect eye from debris
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Eyelids
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Wipers clear debris/lubricate eye
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Tarsal Glands
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Secretions lubricate eyelid
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Lacrimal Gland
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- Produce tears that lubricate/protect
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Lacrimal Apparatus
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produces, distributes and removes tears
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The Eye
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Visual sensing apparatus
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Fibrous Tunic (outer layer)
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Provides support/protection
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Sclera
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- White of eye with increased collagen/elastic
- Vascularized/innervated |
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Cornea
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- Transparent w/ ^^ collagen/elastic
- Not vascularized |
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Vascular Tunic (middle layer)
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Controls lens shape, light entry, and aqueous humor production
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Iris
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controls light entry by changing pupil (aperture) diameter
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Pupilary Constrictor Muscles
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concentric muscles contract = decrease pupil size
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Pupilary Dilator Muscles
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radial muscles contract = increase pupil size
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Ciliary Body
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- Has attachment sites for suspensory ligaments which hold lens
- Has ciliary muscles (change lens shape) (concentric muscle) |
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Choroid
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Contains capillaries/nerves
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Neural Tunic (inner layer)
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- retina
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Pigmented Region
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absorbs stray light (prevents echoes)
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Neural Region
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- Has photoreceptors that detect light
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Rods
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function in low light intensity - No color discrimination
- Increase [] around retinal periphery |
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Cones
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function in high light intensity - Color discrimination (RGB)
- Increase concentration in fovea of macula lutea |
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Accessory cells Bipolar Cells (bc)
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- Link photoreceptors w/ ganglion cells
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Ganglion Cells (gc)
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- Gc axons bundle and exit eye as the optic disc (blind spot)
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Horizontal Cells
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- Increase or decrease communi. Between pr and bc
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Amacrine Cells
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Increase or decrease communi between bc and gc
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Posterior Cavity
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vitreous body (maintains shape)
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Anterior Cavity
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aqueous humor nourishes lens/cornea
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Lens Accommodation
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lens changes shape to focus on image regardless of distance object is from the eye
-ciliary muscle controls suspensory ligament tension, affects lens shape |
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Ciliary Muscle Contraction
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Lens rounds = focus on nearby object
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Ciliary Muscle Relaxation
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lens flattens = focus on distant object
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Image Reversal
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- Light from each portion of object is focused on diff part of retina
- Brain is capable of compensating for image reversal |
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Visual Acuity
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- Clarity of vision
- Defined as detail seen at 20 feet by person with normal vision |
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Rhodopsin
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Visual pigment absorbs light
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Opsin
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- Membrane spanning protein
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Retinal
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Chromophore can maintain 11-cis or 11-trans shape
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Light Absorption Process
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photon strikes 11-cis retinal -11-cis retinal converted to 11-trans retinal
-opsin activated - -> info sent to CNS |
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Bleaching
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- Breakdown of retinal and opsin
- Enzymatic conversation of 11-trans retinal -> 11-cis retinal require ATP |
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Color Vision
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- Retina contains blue, green and red cones
- Integration of info from these cones provides color discrimination |
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Hearing and Equilibrium
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- Hair cells respond to mechanical movement
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External Ear
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Collects/directs sound
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Auricle
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- Funnel channels sound
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External Acoustic Canal
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- Passage to tympanic membrane
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Tympanic Membrane (tm)
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converts sound waves > mechanical movements
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Middle Ear
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Conducts sound to inner ear
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Auditory (Eustachian) Tube
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Permits pressure equalization
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Auditory Ossicles
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- Bones transfer tm movement to oval window
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Inner Ear
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contain hair cells (receptors for hearing/equilibrium)
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Membranous Labyrinth (ml)
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- Tubes/channels filled with endolymph
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Bony Labyrinth (bl)
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- Dense bone surrounds ml
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Vestibule
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Sense static equilibrium
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Semicircular Canals (sc)
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Sense dynamic equilibrium
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Dynamic Equilibrium
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ability to control body during motion
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Semicircular Ducts (sd)
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tubes within scs -
Ant/post/lateral sds sense rotation |
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Ampulla
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Enlargements at end of each sc
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Crista
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- Raised floor of cells with hair cels
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Cupula
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gel structure "floats" in endolymph
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Hair Cells
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- Contain stereo/kinocilia in cupula
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Dynamic Balance Sensation
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sc moves, endolymph in scd moves > cupula moves > cilia move > signal sent to CNS
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Static Equilibrium
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ability to control body while body is stationary
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Vestibule
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- Between sc and cochlea
Has endolymph filled sacs |
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Utricle
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- Large membranous sac responds to forward/backward head movements
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Maculae
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- Sensory receptors in saccule/utricle
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Otolith
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- Gel matrix + carbonate crystals (statoconia)
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Hair Cells
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- Contain stereocilia/kinocilia embedded in gel matrix
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Static Balance Sensation
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head movement causes otolith to slide > cilia move > signal sent to CNS
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Hearing
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Sense of sound
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Cochlea (detail)
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Snail shaped structure
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Vestibular Duct (vd)
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perilymph filled tube
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Tympanic Duct (td)
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Perilymph filled tube
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Cochlear Duct
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Endolymph filled tube between vd/td
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Organ of Corti
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contains hair cell receptors
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Basilar Membrane (bm)
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- Base of oc below hair cells
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Tectorial Membrane (tm)
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- Gel like roof overlies hair cells
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Hearing Sensation
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sound waves > mech. movement of tm /ossicles > oval window moves > fluid vibrations > bm moves > hair cells strike tm > signal sent to CNS
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Pulmonary Circuit
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Cary blood to gas exchange surface
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Systemic Circuit
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Carry blood to rest of body
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Arteries
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Carry blood away from heart
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Veins
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- Carry blood to heart
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Capillaries
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- Thin vessel connects veins/arteries
- Allow for gas/nutrient exchange |
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Pericardium
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Lining of pericardial cavity
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Visceral Pericardium (vp)
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Covers surface of the heart
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Parietal Pericardium (pp)
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Covers surface of pericardial sac
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Pericardial Cavity
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Space between vp and pp
- Contains pericardial fluid (lubricant) |
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Epicardium (vp)
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Mesothelium + connective tissue
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Myocardium
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Muscle tissue + nerves/ blood vessels
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Endocardium
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- Endothelium + connective tissue
-lines inner chamgers of heart |
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Cardiac Muscle Tissue
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cells are small, branched, striated and mononucleated
-cells join at intercalated discs (with gap junctions) |
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Auricles
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- Extensions of atria
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Atrioventricular (Coronary) Sulcus
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Groove between atria/ventricles
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Interventricular Sulcus
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Groove between ventricles
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Right Atrium (ra)
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receives deO2 blood from systemic circuit via superior/inferior vena cava
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Right Ventricle
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receives deO2 blood from ra -pumps deO2 blood into pulmonary circuit (pulmonary arteries) at lower pressure
-has trabeculae carneae (ridges) |
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Tricuspid Valve
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- Three cusps, chordae tendineae attach cusps to papillary muscle
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Pulmonary Semilunar Valve
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- Three cusps
- Guards pulmonary trunk/arteries |
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Left Atrium (la)
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receives O2 blood from pulmonary circuit via pulmonary veins
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Left Ventricle
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receives O2 blood from la -pumps O2 blood into systemic circuit at higher pressure (thicker muscle)
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Bicuspid Valve
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- Two cusps chordae tendineae attach cusps to paiillary muscle
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Aortic Semilunar Valve
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Three cusps
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Coronary Arteries
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- Supply O2 blood to atria/ventricles
- blood enters |
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Coronary Veins
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drain deO2 blood from heart
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Conducting Cells
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control/coordinate heartbeat as ap moves thru conducting system
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Contractile Cells
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ap produce contractions/propel blood
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Sinoatrial (SA) Node
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- Has pacemaker cells - establish hr
- In right atrium |
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Internodal Pathways
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- Connect SA/AV nodes
- Pass ap to atrial contractile cells |
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Atrioventricular (AV) Node
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- Ap is delayed
- atria contract In floor of right atrium |
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Atrioventricular Bundle
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- Moves ap down interventricular septum
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Bundle Branches
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moves ap down interventricular septum-
ap moves to moderator band: papillary muscle contracts, chordae tendinae (ct) tense, keep cusps from flipping back into atria |
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Purkinje Fibers
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- Ap moves across ventricles
- Contraction from apex to base |
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Action Potential Depolarization
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- Sodium channel open fast, Na moves in
- Ca+ channels open slow, Ca moves in while Na pumped out |
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Repolarization
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- Ca channel close slow, K channel open slow, K moves out
- Tp restored, K channels close slow |
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Absolute Refractory Period
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membrane can’t respond to 2nd stimulus
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Relative Refractory Period
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membrane can respond to greater than normal 2nd stimulus
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Electrocardiogram (ECG)
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Monitors electrical activity
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P Wave
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- Corresponds to atrial depolarization
- Atria contract after P peak |
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QRS Complex
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- Corresponds to ventricular depolarization
- Ventricles contract after R peak Atrial repol. Occurs (masked) |
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T Wave
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- Corresponds to ventricular repolar.
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PR Interval
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- From start of atrial depol to start of ventricular depol
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QT Interval
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- From start of ventricular depol to end of vent. Repol.
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Atrial Systole
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atria contract and “top off” ventricles with blood
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Atrial Diastole
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Atria relax
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Ventricular Systole
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ventricles contract, Pventricles > Patria, AV close, Pventricles > Paorta or pulmonary trunk, SLs open, blood fills aorta or pulmonary trunk
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Ventricular Diastole
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Patria > P ventricles, SLs cloes, AV's open, passive filling of ventricles
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Heart Sounds
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Use stethoscope to hear heart sounds
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First Heart Sound (S1/Lubb)
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- AV valves closing
Start of ventricular systole |
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Second Heart Sound (S2/Dupp)
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- SL valves close
- Start of ventricular diastole |
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Cardiodynamics
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movements/forces during cc
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End Diastolic Volume (EDV)
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- Blood volume in each ventricle at end of ventricular diastole
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End Systolic Volume (ESV)
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- ^ at end of ventricular systole
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Stroke Volume (SV)
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- Blood volume pumped from each ventricle in one heart beat
- EDV-ESV |
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Cardiac Output (CO)
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- BV pumped from each ventricle in one minute
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Neural Control of Heart Rate
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centers in medula receive chemical/pressure info-SA/AV nodes innervated
-acetylcholine opens K+ channels, slows depolarization = ¯ hr -norepinephrine opens Na+,Ca+ channels, speeds depolarization = hr |
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Arteries
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- Carry blood away from the heart
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Arterioles
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- Smallest branches of arteries
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Capillaries
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- Smallest vessels (gas exchange)
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Venules
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- Smallest branches of veins
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Veins
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- Carry blood toward heart
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Tunica Intima
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- Inner endothelial layer + ct
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Tunica Media
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- Middles muscular layer + ct
- Controls vessel diameter |
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Tunica Externa
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Outer layer provides support
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Artery Detail
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thicker walls, smooth muscle
- Expand under high pressures. = decreased capacitance |
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Elastic Arteries (ea)
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transport blood volume= diameter - Transport increased blood volume = increased diameter
- Increased elastic fibers = increased resilience = tolerate pressure changes |
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Muscular Arteries (ma)
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contain smooth muscle, change diameter - Deliver blood to tissues
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Arterioles
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contain smooth muscle, change diameter (smaller diameter than ma)
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Capillary Detail
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- Endothelial tube + basal lamina
- No tm or te - Smallest diameter, permit gas/nutrient exchange |
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Continuous Capillary
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complete endothelial lining - Permits small solute/ H2O diffusion, prevents cell/protein movement
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Fenestrated Capillary
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porous endothelial lining - Permits larger solute/H2O/small peptide diffusion
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Thoroughfare
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- Typical capillary bed
- Connections between arterioles and venules |
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Metarteriole Region
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- Contains a lot of smooth muscle with precapillary sphincters (control flow)
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Arterial Anastomosis
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Two arteries (collateral) feed a capillary bed
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Arteriovenous Anastomosis
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- Arteriole/venule connect, bypass capillary bed
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Vein Detail
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thinner walls, ¯ smooth muscle-Expand under low pressure = increased capacitance
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Venules
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smallest diameter of veins - Smallest diameter of veins
- Lack tunica media - Have valves (one way flow) |
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Medium Sized Veins
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- Thin tunica media, tunica externa with more elastic/collagen
- Have valves (one way flow) |
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Large Veins
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Largest diameter of veins
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Blood Flow
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Based on many factors
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Blood Pressure
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- Increase pressure = increase flow
- Decrease pressure = decrease flow |
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Vessel Resistance
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- Increase resistance = decrease flow
- Decrease resistance = increase flow - Dependent on multiple factors |
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Vessel Diameter
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- Increase diameter = decrease resistance
- Based on smooth muscle contraction/relaxation - Friction |
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Vessel Length
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- Increase length = increase resistance
- Does not change appreciably - Baby -> adult - Massive weight loss/gain - Friction |
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Blood Viscosity
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- Based on (suspended materials)
- Increase viscosity = increase resistance 5x more than water |
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Blood Turbulence
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- Swirling of blood (mostly seen A -> V)
- Increase turbulence = increase resistance |
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Arterial Blood Pressure
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Control/coordinate heartbeat
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Systolic Pressure (sp)
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- Max bp at ventricular systole
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Diastolic Pressure (dp)
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- Min bp at ventricular diastole
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Pulse Pressure (pp)
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- Difference between sp and dp
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Mean Arterial Pressure (MAP)
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- Average bp, MAP = dp + (pp/3)
- SP = 120 mmHG, dp = 99mm HG, MAP? |
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Venous Pressure (vp)
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vp is ¯ = ¯ flow, diameter = flow-venous return helped by many factors
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Skeletal Muscle Contraction
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- VP is decreased = decrease flow diameter
- Increases = increased flow Venous return helped by many factors |
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Valves
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- Contractions push blood through veins
Fainting |
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Respiratory Pump (thoracic cavity)
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- Movement of tc helps move blood
- TC expands = reduced pressure, reduced pressure = more air flow = pulls blood into S/IVC - TC compresses = more pressure; air out = pulls blood into RA |
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Capillary Pressures
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- Affect capillary exchange
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Net Hydrostatic Pressure (NHP)
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- Pushes H20/solutes from blood .> IF
- FILTRATION |
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Net Colloid Osmotic Pressure (NCOP)
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- Pulls H2O/solutes from IF -> blood
- REABSORPTION |
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Net Filtration Pressure (NFP)
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NFP= NHP - NCOP
-if + then fluid/solutes move from blood > IF (filtration) -if - then fluid/solutes move from IF > blood (reabsorption) |