Study your flashcards anywhere!

Download the official Cram app for free >

  • Shuffle
    Toggle On
    Toggle Off
  • Alphabetize
    Toggle On
    Toggle Off
  • Front First
    Toggle On
    Toggle Off
  • Both Sides
    Toggle On
    Toggle Off
  • Read
    Toggle On
    Toggle Off
Reading...
Front

How to study your flashcards.

Right/Left arrow keys: Navigate between flashcards.right arrow keyleft arrow key

Up/Down arrow keys: Flip the card between the front and back.down keyup key

H key: Show hint (3rd side).h key

A key: Read text to speech.a key

image

Play button

image

Play button

image

Progress

1/74

Click to flip

74 Cards in this Set

  • Front
  • Back
Centrifugation of whole blood yields:
an upper layer, a middle layer, and a lower layer.
The upper layer of centrifuged whole blood is the:
plasma
the middle layer of centrifuged whole blood:
buffycoat, WBC's and platelets
the bottom layer of centrifuged whole blood:
red blood cells
the formed elements of blood are the
cellular components
the cellular components of blood consist of
red blood cells, white blood cells and platelets.
the fluid portion of blood is the
plasma
the percentage of red blood cells of the total blood volume is called the:
hematocrit
the normal hematocrit (percentage of red blood cells of total blood volume) is
45%
plasma makes up what percent of total blood volume
55%
blood volume of the average adult is
5 liters or 8% of their body weight
the viscocity of blood is what to water
4.5 or 5.5 times that of water.
the ph of blood is
7.35 to 7.45
the temperature of blood in teh thorax is
38 degrees C or 100.4 degrees F (core body temperature)
What are the major inorganic solute of plasma?
sodium and chloride
sodium and chloride contribute to what
the osmotic pressure of blood
Plasma proteins make up what percent of plasma
7-9%
The albumin plasma proteins are waht percent of total protein.
60-80%
the albumin plasma proteins are made in the
liver
albumin plasma proteins are important for
maintaining the osmotic pressure of blood
the alpha and beta globulins are made in the
liver
the alpha and beta globulins transport
lipids and fat soluble vitamins in the blood
Gamma globulins are the
blood antibody fractions
what is the normal red blood cell count in the male
5.4 million per cubic millimeter (cmm)
what is the normal red blood cell count in the female?
4.8 million per cubic cmm
what is the higher concentration of red blood cells in the male due to
testosterone
testosterone stimulates what
red bood cell formation
the cells of red blood cells are
biconcave discs.
the red blood cells reasure
7.5 microns in diameter and 2 microns thick
Red blood cells lack
a nucleus adn mitochondria
red blood cells respire
anaerobically
the average life span of a red blood cell
120 days
after about 120 days, teh red blood cell is then
destroyed by the liver, spleen and bone marrow
function of red blood cell
to transport oxygen and CO2
Hemoglobin makes up what percent of fresh wieght (wet weight) of red blood cells
33-34%
the normal hemoglobin content of blood is infants is:
14-20 grams/deciliter (g/100ml)
the normal hemoglobin content of blood in adult males is
13-18g/deciliter
the normal hemoglobin content of blood in females is
12-16g/dl
hemolgobin consists of
red pigment "heme", bound to the protein component globin
the globin portion is made up of
two alpha and two beta polypeptide chains
in a hemoglobin molecule there are
4 hemes
the 4 hemes of a hemoglobin molecule each consist of
a tetrapyrrole (porphyrin) and one iron atome.
in hemeglobin, iron is in the..
ferrous state
in hemoglobin, one molecule of oxygen will
combine with one iron atom
per hemoglobin molecules, there will be how many oxygens molecules?
4
a single red blood cell contains how many hemoglobin molecules:
250 million
a single red blood cell contains how many molecules of oxygen?
one billion
methemoglobin is hemoglobin in which
iron has been oxidized to the ferric form
iron in the ferric form cannot
transport oxygen
a small amount of what is present in red blood cells?
iron in the ferric form
drugs that are oxidizing agents can cause an increase in what
methemoglobin in the red blood cells
Hematopoises refers to the
formation of all blood cells
erythropoisis refers to
specifically to the formation of red blood cells
Hyocytoblast is waht kind of cell
stem cell
hemocytoblasts are present where
in red bone marrow
hemocytoblasts are present in the (specific)
myeloid tissue
hemocytoblasts have the potential to form
any blood cell
the stem cell transforms into the what
proerythroblast
when the stem cell transforms into the proerythroblast, it is commited to
form an erythrocyte
From the proerythroblast, the sebsequent stages of the stem cell are
erythroblast, normoblast, reticulocyte
during erythropoiesis, the erethroblast and the normoblast do waht
make hemoglobin.
the nucleus is lost in the
late normoblast
from hemocytoblast to reticulocyte takes how long
3-5 days
the reticulocyte is the
cell type that enters the peripheral circulation
the reticulocyte matures into
an erythrocyte in two days after release.
reticulocyte blood counts are
an approximation of the rate of red blood cell formation
Materials needed to make red blood cells include:
carbohydrates, lipids, amino acids, iron, vitamin B-12, and folic acid.
what is needed for nucleic acid synthesis?
two vitamins
Iron is stored in the liver as
ferritin or hemosiderin (complexed with proteins)
What is the blood transport protein for iron?
transferrin
What happens when red blood cells lyse at the end of their life span?
some components of hemoglobin are recycled.
The fact that red blood cells lyse at the end of their life span and some components of hemoglobin are recycled is true for...
iron and amino acids that make up the globin portion.
for iron and amino acids that make up the globin portion, what happens to the heme at the end of the life span?
the heme is degraded to bilirubin.
what is bilirubin?
a yellow pigment that gives color to bile