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322 Cards in this Set

  • Front
  • Back
Where are the Adrenal glands?
superior surface of the kidney
Hormones are ____________ chemical messengers.
blood-borne
Hormones control processes like:
Growth/development
Immunity and body defenses
Maintaining nutrient/water balance
How long do the effects of hormones last?
Short-lived or very long lasting
What type of feedback mechanism controls the release of hormones?
Negative feedback mechanism
3 categories of hormones
amino acid-based molecules
steroids
prostaglandins
Hormones can only affect a
target cell or target organ
What must be present for a hormone to work?
receptor protein
How do hormones alter cellular activity?
Changes to plasma membrane permeability
Synthesis of proteins/regulatory molecules
Activation/inactivation of enzymes
Stimulation of mitosis
Major endocrine organs
Pituitary
Parathyroid
Pancreatic Islets
Pineal
Placenta
Thyroid
Thymus
Testes
Ovaries
Adrenal
Do endocrine glands have ducts?
No
Endocrine glands have a rich______
blood supply
Some endocrine organs are solely endocrine but others
share functions with exocrine glands
What is the location of the pituitary gland?
hangs by a stalk under the hypothalamus
How big is the pituitary gland?
the size of a pea
What bone is the pituitary gland near?
The "Turks Saddle" of the sphenoid bone.
Lobes of the pituitary gland
anterior pituitary
posterior pituitary
What type of tissue is the anterior pituitary?
Glandular
What type of tissue is the posterior pituitary?
Nervous
All anterior pituitary hormones:
proteins (or peptides)
act through second-messenger systems
regulated by hormonal stimulus and negative feedback
4 of 6 anterior pituitary hormones are
tropic hormones
What are tropic hormones?
stimulates target organs, which are also endocrine organs
Posterior pituitary hormones are made by _______ in the ________.
neurosecretory cells
hypothalamus
Posterior pituitary is more of a ___________ organ than a _____________ center
Storage
production
Thyroid Gland secretes two hormones:
Thyroid hormone
Calcitonin
Thyroid hormone is made from
Colloid filled follicles
Calcitonin is made from
C cells
Thyroid hormone is two separate hormones
Thyroxine T4
Triiodothyronine T3
T3 is converted to T4 at the ___________
Target tissue
What does thyroid hormone control?
rate glucose is metabolized
general body metabolism
Thyroid hormone functions in normal growth of ____________ and __________ tissue
reproductive and nervous tissue
What substance which is also used in rocket fuel and drinking water?
Perchlorate
What does perchlorate inhibit and what is the result?
the uptake of iodine
reduce thyroid function
What are the symptoms of iodine deficiency?
Metabolic disorders
sluggishness
Coldness
Calcitonin causes blood __________ levels to be _________ by signaling the bones to ________ more.
calcium levels
reduced
absorb
Calcitonin acts as an antagonist to what hormone
parathyroid
Where and at what location is calcitonin made?
C cells adjacent to the thyroid follicles
What hormone is not present in elderly adults?
Calcitonin
Anterior lobe of the pituitary gland is what type of gland?
True gland
Anterior lobe of the pituitary gland releases what hormones?
Growth hormone
Prolactin
Follicle stimulating and lutenizing hormone
Thyrotropic hormone
Adrenocorticotropic hormone
Growth hormone acts directly on the bones and muscles therefore it is not _________
tropic
Growth hormone acts directly on the _____.
Bones and muscles
Growth hormones ___________ on the bones and muscles.
acts directly
Prolactin stimulates ______________ in the ____________ glands.
Milk production
Mammary glands
Follicle stimulating hormone and lutenizing hormone play a role in _________ hormones especially in ________
reproductive
women
Follicle stimulating hormone & lutenizing hormones are tropic or non-tropic hormones?
tropic
Thyrotropic hormones act on the ___________ to regulate _____________.
thyroid gland
metabolism
Thyrotropic hormones are tropic or non-tropic?
tropic
Adrenocorticotropic hormone acts on the ________________.
adrenal cortex
Protein hormones are ___________.
messengers
Protein hormones leave ____________.
the bloodstream
Protein hormones binds a ______________ on the _____________.
receptor
surface of the cell
What type of hormone binds a receptor on the surface of a cell.
Protein hormones
Protein hormones activates a ________.
second messenger
What is the second messenger that a protein hormone activates?
enzyme on the cell membrane
When the protein hormone activates an enzyme what does it activate and what does it cost?
CAMP
costs an ATP molecule
What effect does CAMP have on the cell?
Acts on existing proteins or molecules.
Is the response time fast or slow for a protein hormone? Why?
fast because it acts on existing proteins or molecules in the cell
What stimulates endocrine glands?
Other hormones
Humeral
Nervous system
How do hormones stimulate other endocrine glands?
Endocrine gland targets another endocrine gland to signal the release of another hormone.
How does humeral stimulation of an endocrine gland work?
Through monitoring the blood for different substances.
Stimulated by concentrations of molecules in body fluids, usually blood
How does the nervous system stimulate endocrine glands?
Action potentials end at endocrine glands then neurotransmitters signal the release of a hormone
Hormones are always released in the _____
blood
When are nervous tissue involved in the stimulation of an endocrine gland?
only when they end at the gland
Where are most endocrine glands located in the body?
along the midline
Posterior pituitary is made of what type of tissue
Neural
Hormones made by cells in the hypothalamus are stored in the _______.
Posterior lobe of the pituitary
Pituitary makes two hormones
Antidiuretic hormone
Oxitocin
Antidiuretic Hormone targets________ and helps to conserve _______.
Kidney tubules
water
Oxitocin stimulates __________ by _______.
labor
uterine contraction
Oxitocin is a powerful ________.
Muscle contractin
Thyroid gland is located in the _________.
Base of throat below the Adams Apple
What does the thyroid gland look like?
butterfly shaped with two lobes
What connects the two lobes of the thyroid gland
Isthmus of the thyroid gland
Parathyroid regulates_____________
blood calcium levels
Beside regulating blood calcium levels what does the parathyroid do?
Stimulates kidneys and intestine to absorb more calcium
What is the major regulator of blood calcium levels and stimulates the kidneys to absorb more calcium?
Parathyroid
Where is the parathyroid gland?
posterior of the thyroid gland
How many parathyroid glands are there and where are they?
4 total, 2 on each lobe
Posterior of the thyroid gland
How does the parathyroid gland stimulate the release of calcium from the bone
Release PTH which stimulates osteoclasts to break down bone matrix
What stimulates osteoclasts to break down bone matrix to release calcium in the blood
Parathyroid gland
What stimulates kidneys and intestine to absorb more calcium to help increase blood calcium levels?
parathyroid gland
When the kidneys and intestine absorb more calcium what happens to the blood calcium levels?
Increases
What endocrine organ is located on the superior surface of the kidney?
Adrenal glands
Adrenal glands secrete:
Glucocorticoids
Mineralocorticoids (aldosterone)
Sex steroids (testosterone)
Epinephrine
Noroepinephrine
Which adrenal hormones are secreted by the cortex?
Glucocorticoids
Mineralocorticoids (aldosterone)
Sex steroids (testosterone)
Which adrenal hormones are secreted by the medula?
Epinephrine
Norepinephrine
Adrenal hormones secreted by the cortex are ________.
lipid hormones
Two glucocorticoids
Cortisol
Cortisone
Cortisol is responsible for
long term stress response
What do Glucocorticoids do?
glucose metabolism
release of prostaglandins
reduces swelling
What do Mineralocorticoids do?
Target kidney tubules for re-absorption of ions
regulates blood sodium levels and thus blood pressure
What does aldosterone do?
regulates water balance
Aldosterone is what type of hormone?
mineralocorticoid
What is the major site of the sex steroids?
reproductive organs
Sex steroids are made in _____ amounts throughout ______.
low
life
Androgens are made mainly in the ________
Adrenal glands
Some estrogens are made here -
Adrenal glands
Adrenal medulla is innervated by the
sympathetic nervous system
Adrenal medulla is responsible for
fight or flight response
Catecholamines
Epinephrine (adrenaline)
Nor epinephrine (nor adrenaline)
Dual role of pancreatic islets
digestive
endocrine
Beta cells secrete the hormone
insulin
What secretes the hormone insulin?
beta cell in the pancreatic islets
What does insulin do?
signals cells to take up more circulatory glucose, reducing blood glucose levels
What is the antagonist to insulin?
Glucagon
What does glucagon do?
Causes glucose release from the liver during times or low blood sugar.
What cells secrete glucagon?
alpha cells
Pineal gland is located
in the brains third ventricle
Pineal gland shape
pinecone shaped
What is secreted by the pineal gland?
Melatonin
Melatonin is highest __________ and lowest around __________
night
noon
What is melatonin believed to regulate?
sleep cycle and timing of sexual maturity
Thymus gland is located
in the upper thorax, posterior to the sternum
Thymus gland secretes
thymosin
What does thymosin do?
Helps the thymus act as an incubator for T cells which help boost your immune response
Ovarian hormones
estrogens
progesterone
Estrogens are produced by
Graafian follicles
Estrogens promote the development of
secondary sexual characteristics in females
Progesterone maintains pregnancy by
discouraging contractions
Progesterone is secreted by the
corpus luneum
Testicular hormones secrete ____________ and is necessary for the ________________.
testosterone
production of sperm
Placenta is only present during ________. It ________ & __________ on demand.
pregnancy
grows and degenerates
Placenta works on other ___________________.
endocrine organs
Functions of bones
Structure and support
Protect
Movement
Storage
Blood cell formation
Blood cell formation
Hematopoiesis
Happens within the bone marrow
Bone types
Long bones
Short bones
Flat bones
Irregular bones
Sesamoid bones
Bone Tissue Types
Compact bone
Spongy bone
Epiphysis
End of the bone
Proximal
Distal
Diaphysis
Bone shaft
Epiphyseal line
Junction of Diaphysis and Epiphysis
Remnant of the epiphyseal plate
Periosteum
Give blood vessels a point to attach to
Fibrous covering
Tribeculae
rods of spongy bone
Medullary cavity
Marrow
Thin fibrous lining on the inside of the medulary cavity
endosteum
Osteocytes rest in
Lacunae
Bone matrix
Organic - collagen
Inorganic - Mineral Salts
Hydroxyapatite
Types of Joints
Fibrous
Cartilaginous
Synovial
Fibrous joints
connected by fibrous connective tissue
No movement or some movement
Syndemoses
In fibrous joints where fibers are longer than the distance of the joint and there is movement
Cartilaginous Joints
Bone ends are connected by cartilage
Amohiarthrotic
Synarthrotic
Amphiathrotic
Type of Cartilaginous joint
Pubic symphysis
Intervertebral joints
Synarthrotic
Type of Cartilaginous joint
Joint between the first ribs and sternum
Synovial joints
where articulating bone ends are separated by a joint cavity containing synovial fluid
Synovial joints - location
all the joints of the limbs
4 distinguishing features of synovial joints
Hyaline articular cartilage
Fibrous articular capsule line with a synovial membrane
Joint cavity with synovial fluid
Reinforcing ligaments
Types of muscle
Skeletal
Smooth
Cardiac
Muscle Function
Produce movement
Maintain posture
Stabilize joints
Generate heat
Muscle prefixes
Myo
Mys
Sarco
Muscle function - produce movement
Almost all movement in our bodies are produced by muscle
Muscle function - maintain posture
Skeletal muscle functions make tiny adjustments to maintain posture
Muscle function - stabilize joints
Many joints are poorly fitting and must be stabilized by tendons of skeletal muscles
Muscle function - generate heat
Almost 3/4 of the energy in ATP escapes as heat
Smooth muscle
Involuntary
Walls of hollow organs
Propels substances along a definite pathway
Smooth muscle cells
Spindle shaped with a single nucleus
Arranged into longitudinal and circular layers
Smooth muscle cells have ________, _________ contraction
slow
sustained
Smooth muscle performs ______________ function.
housekeeping
Smooth muscle gross anatomy
Juxtaposed muscle layers allow the organ to change shape easily to move things throughout the body
Cardiac muscle
Striated
Involuntary
Cardiac muscle is only found in the
heart
Cardiac muscle arranged in
Spiral, figure 8 shapes
Cardiac muscle fibers are ____________ cells joined by ___________
Branching
Intercalated discs
Heart contractions are closely __________ and heart beats at a ________ rate set by an internal _____________.
coordinated
Steady
Pacemaker
Skeletal muscle fibers are __________ shaped.
Cigar
Skeletal muscle fibers are __________ cells
multinucleate
Skeletal Muscle is subject to _____________ control.
Can also be _____________.
voluntary
involuntary
Skeletal muscle fibers are __________ together by ________ tissue for _______ and __________.
bundled
connective
strength
support
Skeletal muscles can ________ considerably in ______.
vary
shape
Skeletal muscle fibers can be _________-shaped, ________-shaped or _________.
spindle
fan
circular
Muscle fibers are ____________ in a continuously ____________ fashion.
sheathed
expanding
_________ eventually blend into the _____ or _________ which ________ the muscle to the ________.
Epimysia
tendon
aponeuroses
attaches
bone
Muscle fiber =
muscle cell
Muscle fibers are bundled together into
fascicles
Fascicles are bound together by connective tissue called
Epimyceum
Muscle fibers are wrapped by connective tissue called________ and that is called a ___________
perimycium
Fascicle
_______ and _______ can travel into the fascicles.
Blood vessels
nerves
Epimycia come together to form a _______.
tendon or aponeuroses
Plasma membrane in muscle is called
sarcolemma
Long specialized organelles with a specialized banding pattern is called a
Myofibril
Myofibril
Long specialized organelles with a specialized banding pattern
Contractil unit of the muscle
Sarcomere
Thin filament of a sarcomere
actin
Thick filament of a sarcomere
myosin
Myosin heads are _________ that link _____ and ______ during contraction.
cross bridges
actin
myosin
_________ are cross bridges that ________ actin and myosin during _______.
Myosin
link
contraction
Myosin contains ______ enzymes which split ______ during contraction.
ATPase
ATP
Muscles are __________ and _________.
contractile
irritable
In order to contract, muscles must be stimulated by a _________.
nerve
_______________ may stimulate a ______ or ________ of muscle cells
Motor neurons
few
100's
Motor unit
One neuron + all of the cells it stimulates
Muscle banding
Dark - A bands
Light - I bands
Myofilaments fron z disk to z disk are repeating units of
sarcomeres
Sarcoplasmic reticulum
Equivalent of endoplasmic reticulum
Sarcoplasmic reticulum stores
calcium
Muscles have the ability to respond to ____________ stimuli
electrical
Neurotransmitter =
messenger
______________ form junctions with the sarcolemma.
Axon terminals
Gap between axon terminal and sarcolemma
synaptic cleft
The synaptic cleft is filled with __________
interstitial fluid
Neuromuscular junction
Axon terminals form junctions with the sarcolemma
A ___________ (Acteylcholine ACh) is released, ___________ across the _______ cleft, & binds to _____________ on the __________.
neurotransmitter
diffuses
synaptic
membrane proteins
synaptic cleft
Muscle neurotransmitter
Acetylcholine, ACh
After ACh binds to membrane proteins the __________ becomes temporarily more permeable to _______.
sarcolemma
Na+ & K+ ions
The electric disruption caused by ACh
action potential
Muscle contractions are a
graded response
Graded muscle contractions can be produced in two ways
Change of frequency of muscle stimulation
Change of number of muscle cells being stimulated
Individual muscle cells have an __________ response to contraction, but whole muscles are made of ________ of ____________.
all-or-none
100's
motor units
Nerve impulses are delivered so _____ that the muscle cannot completely ____ between stimuli.
quickly
relax
Muscle contractions are ___________ together, resulting in _________ and ______ contractions.
summed
stronger
smoother
As stimulation frequency increases, there is no __________ and muscle reaches __________.
relaxation
Fused tetanus
Fused tetanus
Increased stimulation
No relaxation
To provide a _____________ muscle contraction, we _________ the frequency of muscle fiber ________.
smooth, graded
increase
stimulation
Stronger contraction
increase number of muscle cells being stimulated
Working muscles store very limited supplies of
ATP
How many seconds worth of ATP do working muscles store
4-6 s
Muscle fatigue is due to
oxygen debt
Muscle fatigue - Without _________, ___________ will begin to accumulate.
oxygen
lactic acid
No oxygen and _____________ of the muscle tissue will cause the muscle to stop _________.
decreased pH
contracting
____________ must be paid back when muscles fatigue.
Oxygen debt
Lactic acid is cleared from muscle within a few _________
hours
Muscle shortening
isotonic contractions
Tension builds but no sliding
Isometric contractions
Continuous partial contractions in your muscle. Different motor units stimulated in a systematic way
Muscle tone
Muscle tone
Continuous partial contractions
Different motor units stimulated in a systematic way
Three ways to regenerate ATP
Directly in the muscle
Anarobic glycolysis
Aerobic respiration
Regenerate ATP directly in the muscle
Doesn't use oxygen
Doesn't give much ATP
Anarobic glycolysis
Generates lactic acid
Aerobic respiration
Use oxygen
36 ATP per Oxygen
Muscle disuse
atrophy
All muscles _____ at least one _______.
cross
joint
Origin
attachment to an immoveable bone
Insertion
attachment to a movable bone
The bulk of muscle lies
proximal to the joint it crosses
How many attachments do all muscles have?
two
Muscle can't ______ only ______.
push
pull
During contraction the muscle _________ moves toward the ________
insertion
origin
Types of body movements
flexion
extension
rotation
abduction
adduction
circumduction
flexion
decreasing angle between body parts
extension
increasing angle between body parts
circumduction
move in circles
Abduction
moving away from the body
adduction
moving toward the body
Muscle with the major responsibility for a certain movement
prime mover
muscle that opposes or reverses a prime mover
antagonist
muscle that aids a prime mover in a movement and helps prevent rotation
synergist
stabilizes the origin of a prime mover
fixator
Rectus indicates a
straight muscle
Maximus indicates a
large muscle
straight muscle
rectus
large muscle
maximus
4 major regions of the brain
Cerebral hemispheres
Diencephalon
Brain Stem
Cerebellum
Cerebrum has how many hemispheres
2 (duh)
Characteristics of cerebrum
gyri
sulci
fissures
Gyri
Ridges
Sulci
shallow grooves
Fissures
Deep grooves
Ridges of cerebrum
Gyri
Shallow grooves of cerebrum
Sulci
Deep grooves of cerebrum
Fissures
Lobes of the cerebrum
Frontal
Parietal
Temporal
Occipital
Frontal lobe
motor area
Parietal lobe
somatic sensory area
Temporal and occipital lobe
impulses from the body's special sense organs
Motor area of the brain
Frontal lobe
Somatic sensory area of the brain
Parietal lobe
Receives impulses from the sense organs
Temporal and occipital lobe
Visual area of the brain
Temporal lobe
Hearing and olfactory area of the brain
Occipital lobe
Thalmus
Hypothalmus
Hepithalmus
Diencephalon
Diencephalon
Thalmus
Hypothalmus
Hepithalmus
Brain stem
Midbrain
Pons
Medula Oblongata
Reticular formation
Midbrain
reflex centers
Hearing and vision
Pons
Nuclei involved with the control of breathing
Has its own rhythm
Medula oblongata
controls vital visceral activities
Heart
Reticular formation
extends entire length of brain stem involved with visceral motor control
Cerebellum
precise motor control
balance
equilibrium
Spinal cord nerves
Carvical 8
Thoracic 12
Lumbar 5
Sacral 5
Nerves at the end of spinal cord
Cauda Equina
Horses tail
Functions of the nervous system
Monitor changes
Process and interpret
Effect responses
Sensory input
Stimuli are gathered to monitor changes
Nervous system process and interpret
Integrates signals and decides what should be done
Motor input
Activates muscles or glands after sensory input and interpret
Central nervous system - organs
The brain and the spinal cord
Central nervous system - function
interpret incoming signals and issue instructions
Peripheral nervous system
Nerves that extend from the brain and the spinal cord
PNS functional divisions
Sensory (afferent) division
Motor (efferent) division
Sensory division
Afferent - conveys information to the CNS
Motor division
Efferent - carries activating impulses to the muscle of glands effecting a motor response
Motor division is divided into
Somatic motor system
Autonomic motor system
Supporting cells of the nervous tissue
Neuroglia
Types of neuroglia
Astrocytes
Microglia
Ependymal cells
Oligodendrocytes
Astrocyte
1/2 of neural tissue
Liaison between capillaries and neural tissue
Microglia
phagocytic cells that dispose of dibris
Ependymal cells
line brain cavity and spinal cord
Cushions and circulate CSF
Oligodendrocytes
form myelin sheaths around nerve fibers
What is one of the last areas of the brain to mature
Hypothalamus
Formed in the choroid plexuses of the brain
Cerebrospinal fluid CSF
Similar to Blood Plasma
Cerebrospinal fluid
somatic nervous system
What you have control over
The autonomic nervous system is divided into
Sympathetic
Parasympathetic
Sympathetic nervous system
Fight or flight
Parasympathetic nervous system
resting and digesting
Thyroid follicles
hollow structures internal to the thyroid gland
Thyroid hormone targets___________ because all body _________ depend on a continuous supply ________ energy for power.
every cell
cells
chemical
Thyroid hormones are made up of
two - tyrosine amino acid
three or four Iodines
T3 is formed at
target tissue
Calcitonin id produced by
parafollicular cells
Parafollicular cells are found
in connective tissue between follicles
Calcitonin is released in blood in response to
increase in calcium levels
What hormone decreases blood calcium levels?
calcitonin
When blood calcium levels drop what hormone is released by what gland?
Parathyroid hormone
Parathyroid gland
When blood calcium levels are too high what hormone is released by what gland?
Calcitonin
Thyroid
When is Calcitonin released?
When is PTH released?
When blood calcium levels are raised
When blood calcium levels drop
Growth hormone is directed toward
the growth of skeletal muscles and long bones
Growth hormone plays an important role in determining
final body size
Growth hormone is a ___________ sparing ____________ hormone that causes ___________ to be built into ________ and stimulates target cells to ________ in size and _______.
protein
anabolic
amino acids
proteins
grow
divide
While growth hormone stimulates cell growth it also causes _______ to be __________ and used for ________ while sparing ________ to maintain _______.
fat
broken down
energy
glucose
blood sugar
Thyrotropic hormone stimulates the
growth and activity of the Thyroid gland
Gonadotropic hormones
Follicle stimulating hormone
Luteinizing hormone
Follicle stimulating hormone stimulates
follicle development in the ovaries to produce estrogen and sperm development in the testes
Luteinizing hormone triggers
ovulation and causes the rupture follicle to produce progesterone and some estrogen
testosterone by the interstitial cells of the testes
Anterior Pituitary gland is called the ___________ gland because it
master
controls the activity of many endocrine glands