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89 Cards in this Set

  • Front
  • Back

Digestion

- The mechanical and chemical breakdown of foods into forms that cell membranes can absorb

Mechanical Digestion

- Breaks down large particles into smaller ones, but does not change chemical composition

Chemical Digestion

- Breaks down food particles by changing them into simpler chemicals

Digestive System

- Organs of the digestive system carry out mechanical and chemical digestion, as well as ingestion, propulsion, absorption, and defecation

Alimentary Canal

- Consists of organs that extend from the mouth to the anus; the food passageway

Accessory Organs

- Consists of organs that empty secretions into the alimentary canal; food does not pass through them

Alimentary Canal

- A muscular tube about 8 m long


- Passes through the thoracic and abdominopelvic cavities


- Composed of 4 layers

Mucosa

- Innermost layer, mucous membrane

Submucosa

- Nourishes cells, transports absorbed food molecules

Muscularis

- Muscles tissue, moves tube and food materials



Serosa

- Outermost layer; serous fluid eliminates friction

Mixing Movements

- Muscle in small sections contracts rhythmically


- Does not move materials in one direction


- Example: Segmentation

Propelling Movements

- Moves materials in one direction


- Example: Peristalsis

Peristalsis

- Ring of contraction progresses down tube; propels food particles down the tract

Submucosal Plexus

- Controls secretions

Myenteric Plexus

- Controls gastrointestinal motility

Parasympathetic Impulses

- Increase activities of digestive system (secretion and motility)

Sympathetic Impulses

- Inhibit digestive actions (secretion and motility)

Mouth

- First part of alimentary canal


- Ingests food


- Functions as an organ of speech and sensory reception


- Surrounded by lips, cheeks, tongue, palate


- Includes oral cavity and vestibule

Mastication

- Mechanical breakdown of solid particles, mixes them with saliva

Cheeks

- Form the lateral walls of the mouth

- Contain muscles for facial expression and chewing


- Have an inner lining of stratified squamous epithelium (moist)

Lips

- Highly mobile structures that surround the mouth opening


- Sensory receptors judge temperature and texture of food

Tongue

- Thick, muscular organ that occupies the floor of the mouth, and nearly fills the oral cavity when the mouth is closed

Lingual Frenulum

- Connects tongue to floor of mouth



Papillae

- Projections that move food, contain taste buds

Lingual Tonsils

- Lymphatic tissue masses on root of tongue

Palate

- Forms the roof of the oral cavity


- Consists of a hard (bony) anterior part and a soft (muscular) posterior part


- The uvula extends from the soft palate

Palatine Tonsils

- Lymphatic masses on sides of tongue

Pharyngeal Tonsils

- Adenoids


- Masses of lymphatic tissue in posterior wall of pharynx

Teeth

- Hardest structures in the body


- 20 primary (deciduous)


- 32 secondary (permanent)

Dental Caries

- Cavities within enamel of a tooth


- Formed when sticky foods lodge between teeth or in crevices of molars


- Bacteria on teeth metabolize sugars


- Acidic by- products destroy enamel and dentin

Prevention of Dental Caries

- Brush and floss


- Dental exams and cleanings


- Fluoride treatments


- Sealants

Salivary Glands

- Secrete saliva


- Moistens food particles and binds them together


- Dissolves food so it can be tasted

Saliva

- Contains enzymes (begin chemical digestions of carbohydrates) and bicarbonate ions (keep pH favorable for enzyme activity and protect teeth from acidic foods)

Salivary Secretions

- The different pairs of salivary glands have varying proportions of 2 types of secretory cells (serous cells and mucous cells)

Serous Cells

- Produce a watery fluid containing a digestive system called salivary amylase

Salivary Amylase

- Splits starch and glycogen into disaccharides

Mucous Cells

- Secrete mucus

Mucus

- Binds food particles and lubricates food while swallowing

Pharynx

- Cavity posterior to the mouth


- Extends from nasal cavity to esophagus


- As well as the esophagus, it does not help in food digestion


- this cavity and the esophagus have muscular walls, which function in swallowing

Esophagus

- Tubular organ that extends from the pharynx to the stomach


- A muscular food passageway from the pharynx to the stomach


- Penetrates the diaphragm through the esophageal hiatus


- Contains mucous glands in submucosa


- As well as the pharynx, it does not help in food digestion

Lower esophageal (cardiac) sphincter

- Regulates food passage into the stomach

Stomach

- J- shaped, pouch- like organ, about 25-30 cm long


- Inferior to the diaphragm, in the upper- left portion of the abdominal cavity


- Rugae are folds of mucosa and submucosa that allow for distention


- Receives food from the esophagus


- Mixes food with gastric juice


- Initiates protein digestion


- Has limited absorption


- Moves food into small intestine


- Has an inner circular layer


- An outer longitudinal layer


- Some portions have third (innermost) layer of oblique fibers

Gastric Juice

- Gastric glands contain 3 types of secretory cells, which produce this mixture


- Produced continuously

Neural Regulation

- Sympathetic impulses -> Decrease gastric activity


- Parasympathetic impulses -> Increase gastric activity; promote release of histamine, which stimulates gastric secretion

Hormonal Regulation

- Somatostatin -> Inhibits Hydrochloric acid secretion


- Gastrin -> Increases gastric juice secretion


- Cholecystokinin (CCK) -> Released by small intestine cells when proteins and fat enter the small intestine; decreases gastric motility

Gastric Absorption

- Gastric enzyme pepsin beings breaking down proteins


- Wall of stomach is not well- adapted to absorb digestive products


- The stomach does absorb: Some water, Certain salts, Certain lipid- soluble drugs, Some alcohol

Pancreas

- An endocrine gland, secreting insulin & glucagon to regulate blood glucose


- Also an exocrine gland of the digestive system


- In its exocrine function, it secretes digestive fluid called Pancreatic Juice


- Has a large head, that fits into the curvature of the duodenum


- The tail lies against the spleen

Pancreatic Duct

- Along with the common bile duct from the live and gall bladder, empties into the duodenum of the small intestine

Hepatopancreatic Ampulla

- Pancreatic duct and common bile duct join at this dilated tube

Hepatopancreatic Sphincter

- Surrounds ampulla; controls movement of bile and pancreatic juice into duodenum

Pancreatic Juice

- Contains enzymes that digest carbohydrates, fats, proteins and nucleic acids

Components of Pancreatic Juice

- Pancreatic amylase


- Pancreatic lipase


- Trypsin


- Chymotrypsin


- Carboxypeptidase


- Nucleases


- Bicarbonate Ions

Pancreatic Amylase

- Splits starch and glycogen into disaccharides

Pancreatic Lipase

- Breaks down triglycerides

Trypsin

- Digests protein


- Released as inactive trypsinogen, which is activated by enterokinase in small intestine

Chymotrypsin

- Digest proteins


- Released as inactive, activated by trypsin

Carboxypeptidase

- Digest proteins


- Released as inactive, activated by trypsin (form of proteins)

Nucleases

- Digest nucleic acids

Bicarbonate Ions

- Make pancreatic juice alkaline


- Buffer stomach acid

Secretin

- Stimulates pancreas to release pancreatic juice high in bicarbonate ions

CCK

- Stimulates pancreas to release pancreatic juice high in enzymes

Liver

- Largest internal organ


- Located in the upper- right abdominal quadrant, just beneath the diaphragm


- Reddish- brown organ


- Well- supplied with blood vessels

Liver Structure

- Has 4 lobes:


1. Right lobe: Largest


2: Left lobe: Small than right lobe


3. Quadrate lobe: Minor lobe, near gallbladder


4. Caudate lobe: Minor lobe, near inferior vena cava

Hepatic Lobules

- Functional units of the liver


- Consist of plates of hepatic cells radiating out from a central vein


- Hepatic sinusoids run between plates of cells

Hepatic Portal Vein

- Oxygen- poor blood from the digestive tract is transported to the liver through this vein


- It mixes with oxygen- rich blood from the hepatic artery


- This blood filters through the hepatic sinusoids

Hepatocytes

- Adjust nutrient concentrations, as the nutrients from the digestive tract flow by


- Bile produced by hepatocytes leaves the liver through bile ducts

Bile

- A yellowish- green liquid that hepatic cells continuously secrete


- Components are: Water, bile salts, bile pigments, cholesterol and electrolytes

Hepatitis

- Inflammation of the liver


- Many types: chronic or acute


- Some common cause is one of several types of viruses


- Some people have symptoms, and some do not (They can still be carriers)


- Some forms are blood- borne


- Transmitted by contact with food, body fluids or objects contaminated with feces that contain the virus


- Antibiotics are not effective against the virus


- C accounts for about half of all known cases

Gallbladder

- A pear- shaped sac on inferior surface of liver


- It stores and concentrates bile


- Cystic duct from this organ joins with the common hepatic duct from liver to form common bile duct



Gallstone

- Gallbladder normally concentrates bile salts, bile pigments, cholesterol


- Sometimes cholesterol precipitates and forms solid crystals


- Crystals can enlarge


- Causes: excess bile concentration, too much cholesterol secretion by liver, or inflammation of the gallbladder

Hormone CCK (Cholecystokinin)

- Causes the gallbladder to contract, in response to fats entering the duodenum.


- The bile is then released into the duodenum

Small Intestine

- Tubular organ that extends from the pyloric sphincter to the beginning of the large intestine


- Fills most of the abdominal cavity


- Receives chyme from stomach, and liver and pancreatic secretions


- Completes digestion of the nutrients in chyme


- Absorbs products of digestion


- Transports the remaining residue to the large intestine

Parts of the small intestine

- This organ consists of 3 parts:


1. Duodenum: shortest and most fixed portion of small intestine


2. Jejunum: Middle portion, thicker and more active than ileum


3. Ileum: Distal portion; contain's Peyer's patches (Lymph nodules)

Peptidases

- Break down peptides into amino acids

Sucrase, maltase, lactase

- Break brown disaccharides into monosaccharides

Lipase

- Breaks down fats into fatty acids and glycerol

Peristalsis

- Wave-like pushing movements that propel chyme in proper direction down the small intestine

Segmentation

- Ring- like contractions that move chyme back and forth (mixing movement)

Parasympathetic Impulses

- Stimulate both mixing and peristaltic movements, and sympathetic impulses inhibit them

Large Intestine

- Named because diameter is greater than that of small intestine


- 1.5 m long


- At distal, end, opens to outside of body through the anus


- Consists of cecum, colon, rectum, and anal canal


- Has little or no digestive function


- Contains tubular glands containing goblet cells; secrete mucus, the only significant secretion


- Absorbs water and electrolytes


- Forms feces and carries out defecation

Cecum

- Pouch, forms beginning of large intestine


- Appendix is attached; contains lymphatic tissue

Colon

- Ascending, transverse, descending and sigmoid portions

Rectum

- Extends from sigmoid colon to anal canal

Anal Canal

- Last 2.5- 4 cm of large intestine; opens to outside as anus


- Internal and external anal sphincters guard anus

Feces

-Composed of materials not digested or absorbed, and also contain:


1. Water 2. Electrolytes 3. Mucus 4. Bacteria 5. Bile pigments, which provide the color after bacterial alteration


- The pungent color is produced by bacterial compounds, including:


1. Phenol 2. Hydrogen Sulfide 3. Indole 4. Skatole 4. Ammonia

Diverticulosis

- Weakening of intestinal wall leads to protrusion membrane; forms outpouchings that can become inflamed and infected

Inflammatory Bowel Disease

- Group of disorders, including:


1. Ulcerative Colitis: Affects mucosa & submucosa of large intestine; causes blood diarrhea, cramps


2. Chron's Disease: More serious; affects all layers, and occurs in both small and large intestines; causes diarrhea and pain

Colorectal Cancer

- Cancer of the large intestine or rectum


- Fourth most common cancer in US


- Screening tests include fecal occult blood test and colonoscopy