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222 Cards in this Set

  • Front
  • Back
Another name for muscle cells
Muscle fibers
Four basic characteristics of muscle tissue
contractability, excitability, extensibility, elasticity
Types of muscles
Skeletal, Smooth, Cardiac
Is skeletal striated or non-striated?
striated
Skeletal muscles pull or push bones?
pull
Is skeletal voluntary?
yes
Is cardiac striated?
yes
Is cardiac muscle voluntary or involuntary
involuntary
What does cardiac muscle do?
Contractions cause the heart to beat, which propels blood though the blood vessels
What does skeletal muscle do?
Pull bones causing movements around joins
Is smooth muscle striated or non-striated?
non-striated
What does smooth muscle do?
Propels substances through certain organs
Blood vessels, digestive organs, urinary organs, and reproductive organs are lined with what kind of muscle?
smooth muscle
What does peristalsis do?
Propels food from one end of the digestive tract to another
Movement of the body and materials within the body are functions of what types of muscle?
Smooth and skeletal
What is thermoregulation?
heat generation during muscle contraction
Thermoregulation is a function of what type of muscle
Skeletal
Posture, body and organ support, protection from injury are functions of what type of muscle
Skeletal
Cardiovascular pump is a function of what type of muscle
Cardiac
Stabilization and strengthening of joints are functions of what type of muscle?
skeletal
What are myofilaments?
Proteins, actin and myosin, that fill most of the cell
What are 3 common structures for all muscle types?
myofilaments, sarcolemma, sarcoplasma
How does actin filaments work?
The actin filaments can slide past the myosin filament using the energy of ATP, thus shortening [contracting] the muscle.
What is sarcolemma?
The plasma membrane of a muscle cell; specific to the muscle cell
What is sarcoplasma?
The cytoplasm of the muscle cell; specific to the cell
What is epimysium?
The connective tissue of the muscle
What is fascia?
Hypodermis of the skin
How continuous is the epimysium?
It is continuous throughout the hypodermis of the skin
What is a fascicle?
A bundle of muscle
What is a perimysium?
The covering of the fasicle
What is endomysium?
Covering the sarcolemma of each cell
How is the endomysium formed?
When the perimysium thins and weaves around individual muscle fibers
What does the epimysium separate?
individual muscles within a group of muscles
The epimysium is continuous _____?
with the tendon of the muscle it covers
What is a tendon?
tissue that connects muscles to bone
What two things cover skeletal muscle fibers?
Sarcolemma and endomysium
What are myofibrils?
Tubular units along the long axis of the cell (Skeletal)
What are sarcomeres?
The basic structural and function units of contraction in a skeletal muscle cell
Myofilaments
Constructed from thick and thin filaments
Actin
Protein; thin filaments
Myosin
Thick protein filaments;
What do actin and myosin do?
Cause muscle contraction
What are sarcoplasmic reticulum and T-tubules?
specialized smooth endoplasmic reticulum and myofibrils that aid the influx of calcium for coordinated contraction of sacromeres through the myofibrils
Speed of skeletal muscle
Rapid, greater force, relaxes rapidly
Speed of smooth muscle
Slow to contract, sustains its force of contraction (though weaker) relatively longer than skeletal muscle, relaxes slowly
what is the Neuromuscular Junction?
The connection between the sarcolemma of the skeletal muscle and the innervating terminal synaptic end bulbs of a motor axon
ACH pathway within NMJ
The ACh receptors of the sarcolemma that respond to the ACh from the axon are the motor end plate. The ACh affects protein channels in the sarcolemma and starts the contraction. AChE within the synaptic cleft stops the effect of the ACh
Motor Unit
Somatic motor axon and its branches that contact motor end plates
What is the origin of a muscle?
The proximal and/or most stable portion of a muscle; tendon usually attaches to a bone
What is the insertion of a muscle?
The distal and/or most mobile portion of a muscle; tendon attaches to bone or to special CT
What is aponeurosis?
Flat sheet of CT
What is the belly of skeletal muscle?
the region of contraction
What is action of a skeletal muscle
When contraction occurs between the origin and insertion (e.g. flexion, abduction, rotation, etc)
Functional classification
amount of mobility
structural classification
type of tissue that binds the joint and whether or not the joint has a joint cavity
Types of functional classification
synarthroses, amphiarthroses, diarthroses
Types of structural classification
Fibrous, cartilaginous, or synovial
Types of fibrous Joints
Suture, syndesmoses, gomphosis
Types of cartilaginous joints
Synchrondroses (hyaline cartilage), symphysis (fibrocartilage),
types of synovial joint
plane, hinge, pivot, condyloid, saddle, ball and socket
What is a synovial joint
Bond ends/parts covered with articular cartilage/within an articular capsule lined with a synovial membrane
6 Common features of a synovial joint
1. Articular cartilage of hyaline cartilage; absorbs compression
2. Joint of synovial cavity "potential space that holds synovial fluid
3. Articular Capsule - composed of an outer fibrous capsule of dense irregular tissue
4. Synovial fluid - viscous fluid made from blood and fibroblasts that lubricate the jont and nourish the articular cartilage
5. Reinforcing ligaments and articular discs can be extracapsular or intracapsular
6. Nerves and blood vessels - nerves detect pain and movement or stretching; blood supply nourishes tissues and synovial fluid production
Proprioception
determining position for balance
What are bursae and tendon sheaths
fibrous coverings that contain synovial fluid and are associated with synovial joints
Gliding movement
flat surfaces of two bones slip across each other
Angular
The angle between two bones is changed (flexon, extension, abduction, adduction)
Rotation
a bone turns around its own long axis (lateral rotation, medial rotation of the thigh)
What is a formed element?
Specialized tissue called blood
Four primary functions of blood
Transport
Regulates internal chemical environment
Clotting
Protection and prevention
Blood is major contributor of? (primary function of blood)
Regulation of the internal chemical environment including osmotic pressures, water content of the tissues and thermoregulation
Transport (primary function of blood)
nutrients and waste materials, oxygen and carbon dioxide, hormones, enzymes, carrier proteins, minerals, lipids, carbohydrates
Clotting (primary function of blood)
reduce blood loss
Protection and prevention (primary function of blood)
prevention and protection from the effects of pathogens and toxins
Composition of blood
plasma & formed elements
Plasma composition
92% water; 7% proteins
What do proteins in blood plasma aid with
aid in hyperosmotic pressure to reduce water loss to tussues and maintain blood pressure
Four Parts of blood plasma proteins
albumins, globulins, fibrinogens, minerals
albumin
transport fatty acids and steroids
globulins
for antibodies made from B cells
What are fibrinogens for?
for blood clotting
What are the formed elements in blood
erythrocytes
erythrocytes consists of?
RBCs, WBCs, and thrombocytes
What do RBCs not have and what does this mean?
a nucleus, mitochondria, and ribosomes; means no mitosis and no aerobic respiration
What is hemoglobin comprised of?
4 globulin molecules, each with an atom of iron.
How does hemoglobin pick up oxygen
the oxygen attaches to the iron in the globulin molecules.
The RBC's "body" permits what three properties?
strength, flexibility, and a relatevly large surface area
What is rouleaux form?
When RBCs stack themselves like coins
What does traveling in rouleaux form allow RBCs to do
they travel through capillaries and can squeeze between cell spaces
ATP is made by the RBCs through which pathway
anaerobically
Where are RBCs removed?
Macrophages via spleen and liver
What are two properties of a granulocytes
All have a lobed nucleus and granules in the cytoplasm
What are agranulocytes?
Have large rounded or bean-shaped nucleus without granules
Types of Granulocytes
neutrophils, eosinophils, basophils,
neutrophils
most numerous, granules are lysogenic enzymes that are neutral to dye; phagocytize pathogenic bacteria and foreign material
What is pus?
dead neutrophils
Eosinophils
Phagocytic but target allergens or parasites; enzyme granules acid stain red
Basophils
rarest; granules stain with basic blue dye; granules source of histamine released in damaged tissue to increase capillary permeability
Monocytes
Largest WBC and phagocytic; becomes free macrophage in tissues after leaving the capillaries
Name the 3 different lymphocytes and what they do
inclues B, T, and Natural killer cells; part of cellular and antibody immune system against specific pathogens or antigens
What are antigens
foreign substance that produces an immune response
tunica externa
mostly elastic fibers and collagen fibers that protect the blood vessel and anchor it to surrounding structures. The tunica externa is infiltrated with visceral nerve fibers [Why?] and, in the larger arteries and veins, has its own blood supply, the vasa vasorum, ("vessels of the vessel"), to supply nutrients and O2 to the tissues of the vessel wall
What is diapedesis?
When WBCs migrate across the endothelium
Hematopoeisis/hemopoiesis
The process of making new blood cells
What tissue produces RBCs, granulocytes, WBCs, and platelets?
Myeloid tissue,
What is the vasa vasorum?
blood vessel of the blood vessel
What tissue can produce granulocytes and platelets?
myeloid and lymphoid tissue
Active marrow sites in adulthood
ilia, sternum, and bodies of vertebrae
3 Properties of Elastic or Conducting Arteries?
1. Largest arteries with an internal elastic membrane, great amount of elastic tissue in the tunica media and relatively less smooth muscle
2. Largest lumen; allows them to conduct blood from the heart to the muscular arteries
3. Examples? Pulmonary trunk, aorta, brachiocephalic, common carotid, subclavians, and common iliac arteries..
What is the Mediastinum?
The region between the lungs
3 Properties of Muscular or Distributing Arteries
1. Medium to small-sized arteries (arterioles) that distribute blood to specific body parts or organs.
2. Their tunica media contains relatively more smooth muscle and less elastic tissue than elastic arteries. The smooth muscle is also subject to vasoconstriction and vasodilation.
3. Examples: External & internal carotids, axillary, brachial, radial, femoral, tibial.
The superior part of the heart is called ?
The base
part of the heart that is aimed inferiorly towards the left hip and rests on the diaphram
apex
2 Properties of collateral circulation
1. Venous return to the heart is improved by collateral circulation.

2. Most parts of the body receive blood from more than one arterial branch, called an arterial anastomosis. Arteries that do not anastomose, e.g., those supplying the toes and fingers, are called end arteries. If their blood flow is permanently stopped, the cells supplied will die. Think of the effects of frostbite or diabetes
surface of the heart that is the surface of the right atrium and ventricle
Sternocostal surface
What is serous pericardium?
A thin, double-layered serous membrane
Arterial anastomosis
receiving blood from more than one arterial branch
What is the pericardial sac
a thin, double layered serous membrane
serous pericardium
thing, double layered serous membrane
What are end arteries
Arteries that do not anastomose
External layer of the double layer of the heart
parietal pericardium
What is visceral pericardium
where the parietal layer reflects over the hearts surface; also known as epicardium
Pericardial cavity
potential space between the visceral and parietal pericardia
Four properties of capillaries
1. The average lumen diameter is 0.01 mm (10 microns), large enough for RBCs to slip through in single file or in roleaux formation.

2. Purpose: Exchange nutrients, O2/ CO2 and waste products with cells

3. Precapillary smooth muscle sphincters can constrict, cutting off blood flow through the preferred channel of a capillary bed; instead blood flows through the arteriovenosus anastomoses . This is also called vasoconstriction.

4. Capillaries may be continuous, fenestrated or sinusoids. What are the microanatomical differences called clefts or fenestrae? In what organs would each of these types of capillaries be found?
What does the serous fluid within the pericardial cavity do?
lubricates the visceral and parietal pericardia membranes so they can glide smoothly against one another during the heartbeat
Four types of arteries that transport blood away from the heart
1. Elastic or conducting arteries
2. Muscular or distributing arteries
3. Collateral circulation
4. Capillaries
What is the fibrous pericardium and what does it do?
a thick, dense CT covering the pericardial sac; attaches the heart to the diaphram and to the great blood vessels that exit the base
What is the myocardium
The middle layer of the heart wall; mostly cardiac muscle
Most of the blood are in the ____?
Veins 65%-70%
What is the fibrous skeleton
Connective tissue that binds myocardium into bundles
What is the endocardium?
the inner epithelial layer lining the myocardium
Why do veins return blood to the heart without BP?
1. Large size of the lumen offers little resistance to blood flow
2. One way valves in extremeties stop blood from flowing backwards
3. Skeletal muscle compresses veins to push blood to heart
What are intercalculated discs?
A result of adjacent cellular plasma membranes that interlock with the aid of intermediate filaments.
Heart's right side pump is known as the
Pulmonary circuit
Heart's left side pump is known as the
Systemic Circuit
Venous valves
values that stop backflow of blood in veins
Two chambers of the cardiovascular pump have
atrium and ventricle
Describe the pulmonary pump
Blood returning from the body is O2 poor, CO2 rich

Blood enters RA -> RV

Pumps blood to pulmonary arteries to the lungs for gas exchange, adding O2 and removing CO2

Oxygenated blood returns to the left atrium via the pulmonary veins
The liver receives the blood from which two vessels?
Hepatic artery and the hepatic portal vein
Describe the systemic circuit pump
Blood in the
LA -> LV
LV -> Aorta
Aorta branches into systemic arteries, then into increasingly smaller arterties, then finally into capillaries that carry blood to body tissues
Hepatic artery delivers _______ blood for the liver cells
oxygenated
Describe blood returning from capillaries to the heart
O2 deficient blood goes into increasingly larger veins that merge to empty blood into superior or inferior vena cava, which delivers blood to RA
Left and right atria are separated by?
interartrial septum
Atria musculature thin- or thick- walled?
Thin walled
Which veins do the hepatic portal vein collect blood from?
Superior messenteric vein
Inferior messenteric vein
Splenic vein
Apex is formed by the?
Left ventricle
What does the superior messenteric vein do?
Drains the small intestine, portions of the large intestine, and the stomach
Describe cardiac cycle
1. Atria contract (systole) & then relax
2. Ventricles contract (systole) while atria relax (diastole)
3. All four chambers relax
The right AV valve
tricuspid valve
The left AV valve
bicuspid valve
what does the inferior messenteric vein do?
drains the lower large intestine
Collagenous cords that anchor the cusps to the papillary muscles protruding from the ventricular walls
chordae tendineae
lubb dub is produced by?
bicuspid and tricuspid valves (lub)
semilunar valves (dub)
What does the splenic vein do?
drains blood from the spleen, stomach, pancreas, and large intestine
The pacemaker of the heart
Sinoatrial node (SA node); a small mass of specialized cells in the right atrial wall inferior to the opening of the superior vena cava; sets the RESTING heart rate
What can stimulate an increase in heart rate?
1. nerve impulses from sympathetic nervous system
2. noreprinephrine in the blood from the adrenal gland
Hepatic portal vein ______ blood from the veins
collects
Describe the electrical conduction system (pathway) of the heart
SA node-> AV node -> bundle of HIS -> branch to L&R bundle branches -> Purkinje fibers
2 Properties of sinusoids
Relatively large lumens and incomplete endothelial linings
Impulse is received by the AV node in the?
inferior interatrial septum
SA node impulses travel along the?
cardiac muscle cells via the intercalated discs
Purkinje fibers stimulates the?
ventricular myocardium
What is a portal system?
venous system that moves blood from capillaries to veins to capillaries
Bundle of his stimulates the?
interventricular septum
What are the three basic types of blood vessels?
arteries, capillaries, and veins
How many arteries and veins does the umbilical cord consit of?
two unbilical arteries and one umbilical vein
All blood vessels have what kind of epithelium?
simple squamous epithelium aka endothelium
What is the ductus venosus?
A vascular shunt allowing most of the blood to bypass the fetal liver circulation; empties into inferior vena cava
All capillaries are how thick?
one cell thick
What is the smallest branch of artieries?
arterioles
How many layers do blood vessels have? (except capillaries)
3 capillaries
Blood from the RA of a fetus mostly flows to the? (Describe pathway)
foramen ovale -> LA -> LV; most blood bypasses the RV
Name the three layers of blood vessels
1. inner layer = tunica interna
2. middle layer = tunica media
3. outer layer = tunica externa
What happens to the foramen ovale after birth?
It becomes the fossa ovalis
tunica interna
endothelium with an overlying connective tissue with some elastic fibers. The endothelium is a continuation of the endocardial lining of the heart, the only common layer in all blood vessels, including the capillaries
What is the tunica media?
mostly circular smooth muscle and some elastic c.t., responds to the sympathetic n.s. causing vasoconstriction. Vasodilation occurs when the sympathetic ceases innervation.
What happens to the blood that does enter the RV of a fetus?
it is pumped into the pulmonary trunk, where the ductus arteriosus sends most of the blood into the aorta, bypassing the lungs again
What happens to the ductus arteriosus after birth?
it becomes the ligamentum arteriosum
What is lymph?
Fluid collected by lymph capillaries from leaky capillary and cell fluid
Lymph is not drained from the?
brain, avascular tissue, or marrow
Describe the path of lymph
capillaries -> lymphatic vessels -> larger lymph vessels, ducts -> returned to the circulatory system
What is Lymphoid tissue
Any tissue that produces B lymphocytes; may be in the form of nodes or nodules
Where are nodes found?
in the lymphatic tissue
Where are nodules found?
in the intestinal lining or respiratory lining; Mucosa-Associated Lyphatic Tissue (MALT)
What is Mucosa-Associated lymphatic Tissue?
Nodules found in the intestinal lining or respiratory tract
What is the smallest lymphoid organs?
Lymph nodes containing nodules.
Spleen
Removes RBCs and WBCs
What is "red pulp"
is a reservoir and remover of RBCs in the spleen
What does the thymus do?
it is the source of T lymphocytes; receives pre-T lymphocytes from bone marrow
What do B lymphocytes do?
produce specific antibodies when activated by antigens
What enters the Lymphatic capillaries?
interstitial fluid, ions, some nutrients and proteins and WBCs
What permits the different substances to enter the lymphatic capillaries?
one-way valves
What makes circulation possible in lymph vessels?
Muscle contraction and movement (e.g. milking the vessels)
What kind of muscle is in the larger lymph vessels?
Smooth muscle
Describe the pathway of lymph in Lymphatic vessels
Lymph capillaries -> lypmph collecting vessels ->

Lymph nodes-> lymphatic trunks-> Lymphatic Ducts

Right lymphatic ducts drains the right superior quarter of the body -> right subclavian vein

Rest of the body is drained into thoracic duct -> left subclavian vein

Thoracic duct drains the lower appendages and abdomen and thorax through the **cisterna chyli**
What processes are involved in respiration?
pulmonary ventilation, external respiration, internal respiration
What is pulmonary ventilation?
it involves inhalation and exhalation
External respiration
gas exchange between the alveoli of the lungs and the blood
Internal respiration
gas exchange between the blood and tissue cells
External nares
nose entrance
What are the external nares lined with?
skin that contains coarse hairs that filter large particles from inhaled air
What are the nasal cavities, the sides, conchae, and ethmoid lined with?
ciliated pseudostratified columnar epithelium with many goblet cells
What do goblet cells secrete in the nasal cavities?
mucus that contains lysozymes
What do the capillaries in the CT below the mucous membrane of the nose do?
Heat incoming air that swirls around the conchae and ethmoid
What are the three subdivisions of the pharynx?
nasopharynx, oropharynx, laryngopharynx
Where is the nasopharynx?
posterior to the nasal cavities and extends to the level of the soft palate
What mucous membrane does the oropharynx consist of?
nonkeratinized stratified squamous epithelium
What mucous membrane does the laryngopharynx consist of?
nonkeratinized stratified squamous epithelium
What is the larynx composed of?
9 pieces of cartilage, mostly made of hyaline;

1. Thyroid cartilage
2. Epiglottis
3. True and false vocal cords
What does the thyroid cartilage contain?
the laryngeal eminence which is on the anterior median surface
What is the laryngeal eminence?
Adam's apple
What do the false vocal cords do?
help hold your breath when they are brought together
What do true vocal cords do?
Have elastic tissue and vibrate to produce sound as air passes upwards from the lungs;

Skeletal muscles attach to arytenoids and other cartilages;

tension of cord changes = pitch changes
The trachea divides into the
right and left primary bronchi
What is the trachea lined with
ciliated pseudostratified columnar epithelium
What is the tracheal wall reinforced with?
C-shaped rings of hyaline cartilage
What do the C-shaped rings of hyaline cartilage in the tracheal wall do?
allow the esophagus to expand during swallowing
What part of the lung is the main recipient of inhaled objects?
the right primary bronchus
The walls of alveoli contain what type of epithelial cells?
simple squamous epithelial cells; type I cells
What do the alveolar and capillary walls form?
alveolar-capillary membrane
What do type II cells produce
surfactant fluid
what does surfactant fluid do?
lowers the surface tension of the alveolar fluid
What are the prime movers of inspiration?
The diaphram and external intercostal muscles