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55 Cards in this Set
- Front
- Back
Lymphatic system functions (4) |
1. To return tissue fluid + proteins back to bloodstream from interstitium 2. To transport products of fat digestion (chylomicrons) 3. To filter bacteria + other harmful substances from body's fluids 4. To manufacture lymphocytes + antibodies |
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Lymph |
Clear/straw-coloured fluid circulating in lymphatic system |
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Composition of lymph |
Similar to blood plasma but lower in protein as larger protein molecules cannot leave blood capillaries |
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2 places lymph composition undergoes change |
1. Small intestine - higher levels of fat (chyle) 2. Liver |
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Lymphatic vessels begin... |
In body tissues as tiny mesh of lymph capillaries, slowly link up as they move toward heart |
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2 lymphatic ducts lymph vessels will drain into one of |
1. Right + left lymphatic ducts 2. Cisterna chyll (thoracic duct) |
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Lymphatic ducts drain into |
Cranial vena cava, near right atrium and return fluid to the heart. |
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Lymph nodes |
Small round structures made up of lymphoid tissue, found interspersed throughout lymphatic system |
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Lymph node function |
Filters lymph that flows through as it returns to bloodstream |
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Macrophages in lymph nodes function |
Remove harmful contaminants from lymph |
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Lymphocytes |
Produced in lymph nodes and are released into lymph |
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Lymphocytes enter bloodstream when |
Lymph drains into cranial vena cava |
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Lacteal |
Projection of lymph vessel where digested fat is absorbed |
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Thymus gland |
Important site for T-lymphocyte maturation |
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Tonsils are full of |
Lymphocytes |
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The spleen contains |
Numerous macrophages |
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Gut Associated Lymphoid Tissue (GALT) |
Found in small intestinal mucosa, also known as Peyer's Patches (aggregated lymphatic nodules) |
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Movement of materials to lymph vessels occurs by |
Hydrostatic pressure and osmosis |
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Hydrostatic pressure in capillaries compared to interstitial areas |
30 mmHg compared to 0 |
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The pressure differential between capillaries and interstitial areas does what |
Forced fluids from capillary bed into tissue spaces |
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What will remain within the capillaries even with pressure difference |
Large protein molecules, blood cells and similar materials |
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Lymph vessels transport |
Interstitial fluid to veins of circulatory system |
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As hydrostatic pressure of blood in capillaries drops, the osmotic effect of retained substances increases until |
At venule side of capillary bed it has become half as great as hydrostatic pressure on arterial side |
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Osmotic pressure does what |
Pulls tissue fluids back into bloodstream with dissolved waste products |
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Hydrostasis and osmosis (6) |
1. Pressure differential or capillaries and interstitial areas forces fluids from capillary bed into tissue spaces 2. Large protein molecules, blood cells and similar materials remain within capillaries 3. Hydrostatic pressure of capillary blood drops, osmotic effect of retained substances increases 4. Venule side of capillary bed has become half as great as hydrostatic pressure on arterial side 5. Osmotic pressure pulls tissue fluids back into bloodstream together with dissolved waste products 6. Transference of excess interstitial fluid directly to lymphatic vessels occurs at same time |
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Sinoatrial node/pacemaker |
Electrochemical activator built into cardiac muscle |
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Parts of hearts electrical conduction system (5) |
1. Pacemaker 2. AV node 3. Bundle branches 4. Bundle of His 5. Purkinje fibers |
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Cardiac electrical impulse (7) |
1. Electrical impulse initiated by SA node 2. Impulse spreads out over atria, both contract 3. Depolarizes AV node 4. Conducting fibers (Av bundle or bundle of His) 5. Down right and left bundle branches 6. Bundle of His distributes charge over medial surface of ventricles 7. Contraction of ventricles is stimulated by the Purkinje fibers to the myocardium |
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ECG |
Recording of electrical changes as they accompany the cardiac cycle |
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P wave |
Atrial depolarization — spread of an impulse from SA node through both atria |
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QRS complex |
Atrial depolarization, ventricular depolarization - spread of impulses across ventricles |
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T wave |
Ventricular repolarization |
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First heart sound (3) |
1. Occurs when AV valves close at beginning of ventricular contraction 2. Generated by vibration of blood and ventricular wall 3. Louder, longer, more resonant than second heart sound |
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Second heart sound (3) |
1. Occurs when aortic and pulmonary semilunar valves close at beginning of ventricular dilation 2. Generated by vibration of blood and aorta 3. Aortic valve closes slightly before pulmonary valve |
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Regulation of heart is affected by |
Both sympathetic and parasympathetic stimulation |
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Cardioacceleratory/pressor centre |
A group of neurons within medulla |
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Stemming from cardioacceleratory/pressor centre (path + innervate) |
Sympathetic nerve fibres that travel down a tract in spinal cord and then pass outward in cardiac nerves to innervate SA node, AV node and portions of myocardium |
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Stimulation of cardioacceleratory centre |
Causes nervous impulses to travel along sympathetic fibers. Norepinephrine is released and causes increased HR and strength of contraction |
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Cardio inhibitory centre is made up of |
Parasympathetic fibers (vagus nerve) |
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Stimulation of cardio inhibitory centre causes |
Release of acetylcholine ACh which acts on SA node and AV node, causing decreased HR and strength of contraction |
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Norepinephrine is what |
Catecholamine |
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Baroreceptors |
Nerve cells capable of responding to changes in blood pressure and affect HR |
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Baroreceptors involved in 3 reflex pathways |
1. Carotid sinus reflex (arterial BP) 2. Aortic reflex (arterial BP) 3. Atrial reflex (venous BP) |
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Carotid sinus reflex (4) |
1. Maintains normal BP in brain 2. Baroreceptors in walls of carotid sinus 3. Increase in BP stretches walls - stimulus 4. Decreased HR and strength of contraction -> Decreased cardiac output and arterial pressure |
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Aortic reflex (2) |
1. Baroreceptors in walls of aortic arch 2. Same actions result as carotid sinus reflex |
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3. Right Heart/Atrial reflex (3) |
1. Responds to venous BP 2. Initiated by baroreceptors in caudal vena cava and right atrium 3. When venous BP increases baroreceptors stimulate cardioacceleratory centre |
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Epinephrine (hormonal control) |
Hormone produced by adrenal gland that increases excitability of SA node, and rate + strength of contraction. |
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Thyroxin (hormonal control) |
Released by thyroid gland, increases heart rate. |
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What is necessary for proper cardiac function? |
A proper balance between sodium, calcium and potassium in blood plasma |
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Calcium |
Necesary for contraction of heart muscle. Excess causes increased HR and strength of contraction |
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Potassium |
Interferes with generation of nerve impulses, decreases HR and strength of contraction |
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Sodium |
Interferes with calcium participation in muscle contraction, decreases HR and strength of contraction |
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Chemoreceptor reflex (3) |
1. Stimulated by decreased oxygen and/or pH 2. Stimulated by increased CO2 3. More important in regulating breathing than cardiac function |
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Proprioceptor reflex |
Stimulated by muscle and joint movement, increases heart rate during exercise. |
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Increased body temp vs decreased |
Causes AV node to discharge impulses faster (increased HR) vs. Causes decrease HR and strength of contraction |