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124 Cards in this Set
- Front
- Back
What are the 4 Basic Tissue Types?
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Muscle, Connective, Nerve, Epithelium
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SUPERIOR AND INFERIOR
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ABOVE AND BELOW
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CEPHALAD AND CAUDAD
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HEAD AND TAIL
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ANTERIOR AND POSTERIOR
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FRONT AND BACK
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MEDIAL AND LATERAL
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MIDDLE AND OUTSIDE
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ISPILATERAL AND CONTRALATERAL
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SAME SIDE OR OPPOSITE SIDE
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PROXIMAL AND DISTAL
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NEAR ATTACHMENT OF TRUNK AND DISTANT FROM ATTACHMENT
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VENTRAL AND DORSAL
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BELLY SIDE AND BACK SIDE
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SAGITTAL PLANE
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LEFT AND RIGHT PLANES
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CORONAL PLANE
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FRONTAL PLANE (ANTERIOR AND POSTERIOR PLANES)
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TRANSVERSE PLANE
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SUPERIOR AND INFERIOR PLANES
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TOMOGRAPHY
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cutting slices through the body
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CYTOLOGY
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the study of cells
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DIFFERENTIATION
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development of specialized structures and functions
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INCLUSIONS
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stores droplets of melanin, protien, glycogen and lipid
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NUCLEUS
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command and control center
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CHROMOSOMES
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condensed DNA
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RIBOSOMES
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protein synthesis
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ENDOPLASMIC RETICULUM
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protien processing
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GOLGI APPARATUS
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prosessing and trafficing protiens
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MICROTUBULES
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movement and support
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MICROFILAMENTS
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maintain muscle shape, aid in muslce contraction
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MITOCHONDRIA
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powershouse of cell... ATP production
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PLASMA MEMBRANE
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regulates material movement in and out of cell
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LYSOSOME
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digests materials ingested by cell
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MITOSIS
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somatic cell division
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PROPHASE
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1st phase of mitosis
p is for puffy ball of chromosomes that form in the center of the cell |
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METAPHASE
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2nd phase of mitosis
m stands for middle because chromosomes align along the middle of the cell. |
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ANAPHASE
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3rd phase of mitosis
a stands for apart because the sister chromatids are pulled apart. |
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TELOPHASE
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4th phase of mitosis
t stands for two because two new cells begin to form as a cleavage furrow divides the cytoplasm |
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Epithelia
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Covers and lines surfaces, organs, cavities, and ducts.... Everywhere!
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Connective Tissue
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Support and Storage--Immunity
Fat, Bone, and Blood |
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Muscle
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Movement and Interaction with our Enviroment
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Nervous Tissue
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Coordination of body activity
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3 Layers of Germs
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Ectoderm, Endoderm, Mesoderm 8 days into gestation
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Where is Ectoderm located?
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Nervous System and Epithelia
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Where is Endoderm located?
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Epithelia
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Where is Mesoderm located?
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Epithelia, Connective Tissues, Muscles
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Def of Epithelia:
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Self- Renewing cell population
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Blood Vessels in epithelia?
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No there are no blood vessels in Epithelia... so you won't bleed on the first layer of skin!
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ECM in Epithelia?
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Little or no Extra Cellular Matrix between cells
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How is Epithelia organized?
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In continous sheets (layered or single)
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Epithelia... Polar?
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Yes, each epithelium has an apical surface and a basal surface
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Epithelia Cell Junctions?
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Secure attachments tht allow communication
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List the 4 different cell junctions in the epithelia.
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Tight- competely attaches each cell to the neighbor
Adherens- around the cell Desmosomes/Hemidesomsomes- basement membrane Gap Junctions- small passage way connections |
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Epithelia ... Avascular?
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Avascular... nutrients delivered/ wastes removed via diffusion
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Does Epithilia have its own nerve supply?
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Yeah!
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Epithelia
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high mitotic rate
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Germ Layers for Epithelia...
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All 3 Ectoderm, Endoderm, Mesoderm
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Epithelial Shapes
(Based on Apical layer) |
Squamous
Cubodial Columnar Transitional (in bladder) |
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Epithelial Layers
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Simple(single layers)
Stratified (layered) Pseudo-Stratified Columnar (found in lung) |
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APICAL LAYER
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Free on top of the surface
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BASAL LAYER
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Bottom surface
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Squamous simple
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(scales) floor tiles
lines blood vessels lines body cavities |
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Cuboidal simple
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like bricks
secretion and absorbtion |
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Columnar simple
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Secretion and absorbtion
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Statified Epithelia
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Based on the most apical layer
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Stratified Squamous
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skin and mucous membranes
for waterproofing and protection |
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Startified Cubodial
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sweat glands
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Stratified Columnar
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large excretory glands
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Stratified Tansitional
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Ureters, bladder- allows distenstion and recovery
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Pseudostratified
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single layer, but appears to be stratified but all cells in contract with basement membrane
- upper respritory tract fnx- secretion and movement of mucus coughed out or swallowed! |
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mucous
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lines the body cavity open to the exterior enviroment ex: respritory tract, mouth, anus, eyes
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serous
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lines a body cavity not directly open to the exterior
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synovial
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lines cavities of freely moveable joints
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Connective Tissues
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underneath epithilum fat, bone, cartiagle, tendon, blood
cells -- ecm |
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Connective Tissues have blood supply??
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They all have a rich blood supply except cartilage and tendons
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endothelia
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same as connective tissue with no blood supply
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Cells in Connective Tissues
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Fibroblasts
Macrophages Plasma Cells Mast Cells Adipocytes |
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Fibroblasts
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default CT cell; makes and secrets collagen; responsible for maintain of ECM
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Macrophages
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aka histiocytes
1. fixed in ECM 2. motile= phagocytosis of bacteria, cellular debris, forign objects wander in CT |
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Plamsa Cells
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(immune) derived from WBC's
lives in the connective tissue of GI tract- mammary glands |
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Mast Cells
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Histamine Release
Vastolidation-production/release of heparin-inhibit in blood clotting |
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Adipocytes
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fat storage
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ExtraCellular Matrix (ECM)
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amorphous-active in development, remodeling, repair, and metabolism
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Hyaluronan
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hydroscopic, lubricates joints, facilitates movements of cells
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Collagen
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Repair of the body
Most abundant protein in the body (25% wet weight) Over 14 Types Great Tensile Strengh (doesn't fold under pressure) |
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Elastin
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Found in skin, blood vessels, and lungs
Can stretch to 150% and then recoil |
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Reticular Fibers
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web/net delicate
collegan + various glycoprotiens |
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Skin
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the casing forming the outside surface of a structure
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3 Layers of Skin
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epidermis
dermis subcutaneous |
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Epidermis
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...Stratisfied Squamous Epithielium
4 cell types: i keritinocytes 90% (make new cells) ii melanocytes 8% (sheild DNA from UV) iii langerhans cells iv Merkel cells-immune and sensory |
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Dermis
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composed of connective tissue
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Subcutaneous
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composed of superfacial fascia and hypodermis
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Epidermal Layers
startum basale |
cuboid to columnar
constantly dividing |
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Epidermal Layers
s. spinosum |
Hornly/Prickly
(Next 8 to 10 rows) |
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Epidermal Layers
s. granulosum |
(3-5 layers cells accumulate kertain in keratohyaline granules, lamellar granulars contain lipid- responsible for waterproofing
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Epidermal Layers
s. lucidum |
3-5 rows of flattened kertainocytes nearl full of keratohyaline granules- which is only in thick skin
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Epidermal Layers
s. corneum |
25-30 rows anucleated cells composed almost entirely of cytoskeletal filaments and kertainoaline matrix-- paste to hold death cells
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Contents of the Dermis:
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Adipocytes(fat cells), fibroblasts, microphages, blood vessels cells, hair, nerves, glands.
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Layers of the Dermis
Papillary Dermis |
Papillary Dermis-- nearest to the epidermis
represents 20% of dermal thickness characterized by dermal papillae, indentations into the epidermis contain capillary loops special sensory structures. -Home to the blood vessels |
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Reticular Dermis
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the deeper 80% of the dermis
composed of dense irregular connective tissue collagen and elastin fibrils= strength and resiliency |
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Variations of the skin
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The variations in the thickness of the reticular dermis that account for the difference in the thickness between the thickness of the skin-- heel vs. eye lids
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Functions of the Skin
largest immune and sensory organ |
1. Mechanical Protection
2.Regulation of Body Temp 3. Sensation 4. Excretion and Absorbtion 5.Immunity 6. Blood Reservior (holds 10%) 7.Vitamin D synthesis |
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How does the color of the skin form?
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Due to melanocytes in epidermis
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What does the amount of melanin synthesized do?
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is the basis of basic skin pigmentation
but everyone has the same amount of melanin |
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vitiligo
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genetic absense of melanocytes from areas of the skin
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Composition of Bone
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Mineral Salt- 50%
Protien- 25% Water 25% |
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Ceruminous Glands
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earwax protection
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Functions of the Bones:
Support |
site for attachments (muscles and organs)
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Functions of the Bones:
Protection |
ribs, vertebrae (internal organs) skull (brain) invovles axial skeleton
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Functions of the Bones:
Movement |
muscle contraction changes the andles between bones at joints, producing skeletal/body movement
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Functions of the Bones:
Mineral Storage/Release |
Ca2, P, Mg2
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Functions of the Bones:
Blood Cell Production |
Hematopoiesis
takes place in bone marrow |
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Functions of the Bones:
Energy Storage |
in fat cells of bone marrow
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Osteoprogenitor
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Bone cell
capable of division found in cells of periosteum and endosteum |
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Osteoblast
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Bone cell
differentiatd cells that produce new bone matrix (start to lay down bone-- do not divide) Continuously add matrix |
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Osteocytes
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Bone cell
an osteoblast "trapped" in its own matrix maintenance and mineralization of bone |
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Osteoclasts
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Bone cell
bone reabsorbtion and remodeling responds to hormones that regulate blood Ca2 levels Continuously remove matrix |
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Periosteum
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(Bone) fibrous outer layer+ osteogenic inner layer (like shrink wrap)
-site of ostroprogenitor cells which are deep in the skin! |
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Epiphysis
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site of bone to bone connections (enlarged to strenghthen joint)
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Diaphysis
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(shaft) the length of the bone
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Metaphysis
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(Epiphyseal plate) site of new bone growth
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Medullary (marrow) cavity
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site of hematopoiesis and fat storage
(hollow site in the shaft of the |
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Endosteum
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innermost lining of bone- contains ostroblasts and osteoclasts
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Compact Bones
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external layers of all bones.. esp shaft of long bones
solid and dense |
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Compact Bones
Organization?? |
Stuctural Unit: Osteon(Haversian System)
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Haversian Canal
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Lies within the osteon and runs parallel to it; traveling within the canal are the blood vessels, nerves, lynph vessels, which are supplied to the bone
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Concentric Lamella
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Mineralized matrix in concentic rings look like small plates that surround the osteon
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Interstitial Lamella
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Areas between osteons represent older, partially "remodeled" osteons, They have been partially reabosbed and do not have a cental canal
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Lacunae
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Spaces that house an osteocyte and are connected by canalicuil
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What are Canaliculi?
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connect the lacunae and permit passage of O2 and CO2, wastes and nutrients
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Volkmann's Canal
aka perforating canals |
(perp to bones long axis) allow entry of blood vessels/nerves into interior of bone
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Spongy Bone: Cancellous
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Pericentral region of most long bones and short flat and irregular shaped bones ei- sternum, clavicle, carpals
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