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92 Cards in this Set
- Front
- Back
the primordium of the heart forms from which germ layer?
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the splanchnic layer of the lateral plate mesoderm
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does the primordium of the heart form at the rostral or caudal end of the embryo?
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rostral
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which cell clusters coalesce to form the right and left endocardial tubes?
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angiogenic cell clusters
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where are the angiogenic cell clusters located?
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in a horse-shoe shape around the neural plate
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which embryonic feature becomes the pericardial cavity?
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intraembryonic coelom
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the dorsal aortae develop on either side of which embryonic structure? They become continuous with which structures?
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notochord; endocardial tubes
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why are the endocardial tubes forced into the thorax?
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longitudinal folding
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what effect does lateral folding of the embryo have on the endocardial tubes?
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brings them together in the midline where they fuse together
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what is the name for the structure which arises from the fusion of the two endocardial tubes in the embryo?
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primary heart tube
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at which ends of the endocardial tubes does fusion not occur?
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caudalmost
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the primary heart tube is suspended in the primitive pericardial cavity by what structure?
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dorsal mesocardium
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what is the fate of the dorsal mesocardium?
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it breaks down so that the primary heart tube is completely surrounded by pericardium
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the primary heart tube is anchored in the pericardium by its connections with which structure? Is this connection cranial or caudal?
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dorsal aortae; cranial
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the primary heart tube is connected with which structure at its caudal end?
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vitelloumbilical veins
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what is the name of the caudalmost expansion of the primary heart tube? What forms the caudalmost structure of the primary heart tube?
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primitive atrium; sinus venosus
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what are the two main components of the sinus venosus?
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right and left sinus horns
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which veins drain into the right and left sinus horns?
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common cardinal veins
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in the primary heart tube, which sulcus lies cranial to the primitive atrium?
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atrioventricuar sulcus
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what does the atrioventricular sulcus form internally?
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atrioventricular canal
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which expansion of the primary heart tube is cranial to the primitive atrium and the AV sulcus?
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primitive ventricle
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which atrium does the primitive atrium eventually become?
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both left and right
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which ventricle does the primitive ventricle eventually become?
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the left ventricle
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the interventricular sulcus of the primary heart tube divides which two expansions?
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primitive ventricle and bulbus cordis
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what does the interventricular sulcus form internally?
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interventricular septum
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what are the 3 parts of the bulbus cordis?
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bulbus cordis, conus cordis, truncus arteriosus
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what structures of the heart does the bulbus cordis become? The conus cordis? The truncus arteriosis?
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right ventricle; outflow tract of both ventricles; roots and proximal parts of aorta and pulmonary trunk
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at its superior end, to what is the truncus arteriosus connected?
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first aortic arch
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what is the result of having the caudal and cranial ends of the heart tube anchored in the pericardium?
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when it elongates, it is forced to bend and twist on itself
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in the normal folding of the heart, the cephalic portion of the heart tube bends ________, ________, and to the ________ while the caudal portion bends ______, ________, and to the _______.
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ventrally; caudally; right; dorsally; cranially; right
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how does the atioventricular canal change orientation during cardiac looping?
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it shifts medially so it is in touch with both ventricles and not uniquely the left ventricle
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what is the name for the first part of the interatrial septum?
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septum primum
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which features appear in the area of the AV canal as it moves medially?
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endocardial cushions
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the septum primum grows from where to where?
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dorsal wall of primitive atrium to endocardial cushions of AV canal
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what is the name of the opening formed by the free end of the septum primum?
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ostium primum
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to which features of the AV canal does septum primum bind?
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endocardial cushions
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what happens as septum primum binds to endocardial cushions?
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perforations appear in the upper portion of the septum primum
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the perforations of the septum primum coalesce to form what structure of the embryonic heart?
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ostium secundum
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what is the name of the septum which forms immediately to the right of the septum primum?
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septum secundum
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which of the interatrial septa does not completely form a partition in the atrial cavity?
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septum secundum
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what is the name for the gap left in the septum secundum? This allows for communication between which chambers of the heart?
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foramen ovale; left and right atria
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in the cardiac loop, what separates the two future ventricles of the heart?
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interventricular sulcus
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which divide the atrioventricular canal?
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endocardial cushions
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what happens in the region of the interventricular sulcus to help separate the two ventricles?
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muscular tissue begins to protrude into the cardiac lumen from the floor of the ventricles towards the endocardial cushions
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which two events characterize the formation of the membranous part of the interventricular septum?
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further growth of the endocardial cushions and downgrowth from the septum that divides the truncus ateriosus
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the cardiac outflow pathway is divided into two by right and left _______________ that grow from opposite walls of the ____________________ and the __________________.
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truncoconal swellings; conus cordis; truncus ateriosus
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what is the name for the septum which forms to separate the two major outflow tracts of the right and left ventricles?
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aorticopulmonary septum
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how does the aorticopulmonary septum develop?
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as a spiral
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separation of the aortic and pulmonary outflow tracts becomes complete when the truncoconal swellings fuse with the ______________ and _________________.
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endocardial cushions; interventricular septum
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initially, how does blood enter the heart tube?
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sinus venosus
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which three veins drain into each horn of the sinus venosus?
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common cardinal veins, vitelline veins, and umbilical veins
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the vitelline veins drain blood from where in the embryo?
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yolk sac and derivatives of the gut tube
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the vitelline venous system gives rise to what? This carries blood from where to where?
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liver sinusoids; gastointestinal tract to liver
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on the visceral suface of the liver, the ductus venosus shunts blood from where to where?
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umbilical vein to inferior vena cava
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umbilical veins bring blood from where?
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placenta
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the right sinus horn becomes the most proximal portion of the ___________ and _________________.
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inferior vena cava and superior vena cava
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what happens to the sinus venosus as the heart is enlarging?
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the right side is incorporated into the posterior wall of the developing atrium
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what is the name for the part of the sinus venosus that becomes part of the right atrium?
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sinus venarum
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what is the destiny of the portion of the primitive atrium which is displaced by the sinus venarum?
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right auricle
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what is the name for the line which divides the smooth and rough aspects of the right atrium?
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crista terminalis
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what is the destiny of the left sinus horn?
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coronary sinus
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the pulmonary veins sprout from the _________________ and grow towards the lungs.
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primitive atrium
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which vessels are reabsorbed by the left atrium and displace the original aspect of the atrium, forcing it to become the left auricle?
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pulmonary veins
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what are the components of the arterial system of the embryo?
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dorsal aortae and aortic arch arteries
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as the longitudinal folding forces the endocardial tubes into the ventral thorax, what happens to the paired dorsal aortae?
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they are pulled ventrally to form a pair of dorsoventral loops
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the dorsoventral loops formed by the dorsal aortae form what aspect of the arterial system?
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1st aortic arch
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the aortic arches develop in which succession?
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craniocaudal
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the embryonic aortic arch system is eventually remodeled to form what?
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system of great arteries in the upper thorax and neck
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the 4th aortic arch undergoes assymetric remodeling. On the right side, the 4th aortic arch loses its connections with the ___________ and the ______________ and contributes to the ______________________.
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dorsal aorta; 6th aortic arch; right subclavian artery
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the proximal parts of the 6th aortic arch form what?
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pulmonary arteries
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from which embryonic structure does the pulmonary trunk develop?
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truncus arteriosus
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on the ____________ side, the distal part of the 6th aortic arch disappears and on the _________ side, the distal part forms the _______________.
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right; left; ductus arteriosus
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what is responsible for the assymetry of the left and right recurrent laryngeal nerves?
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asymmetric development of right and left aortic arches
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the right and left recurrent laryngeal nerves arise where? The left nerve is caught under where? The right?
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below the level of 6th aortic arch; 6th aortic arch; 4th aortic arch
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the dorsal aortae fuse in the region of the aortic arches to form what?
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descending aorta
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the foramen ovale shunts blood from which chamber to which other chamber?
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right to left atrium
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which feature shunts blood from the pulmonary artery to the descending aorta?
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ductus arteriosus
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what does the ductus venosus shunt? What does it bypass?
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oxygenated blood from umbilical vein directly to the inferior vena cava; the liver
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are the foetal lungs high or low resistance? Adult lungs?
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high; low
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what happens upon the first breath of a newborn?
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lungs expand, pulmonary vessels open, and resistance of pulmonary circuit drops
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the closure of umbilical veins results in the formation of what?
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ligamentum teres hepatis
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the closure of umbilical arteries results in the formation of what?
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medial umbilical ligaments
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which pressure changes in the atria cause the foramen ovale to close?
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larger pressure in the left atrium and reduced pressure in the right atrium
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what is the name for the remnant of the foamen ovale?
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fossa ovalis
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the closure of the ductus arteriosus results in the formation of what?
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ligamentum arteriosus
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the closure of the ductus venosus results in the formation of what? Where is this?
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ligamentum venosum; fissure on the visceral surface of the liver at the root of the lesser omentum
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what is coartation of the heart? What are they two catagories?
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severe constriction of the aorta in the regions of the ductus arteriosus; pre-ductal or post-ductal
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what is the most common form of an atrial septum defect (ASD)?
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a probe patent foramen ovale where the septum primum and the septum secundum form an incomplete seal
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in which portion of the interventricular septum is a ventricular septal defect normally found?
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membranous portion
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what is the problem in a patent ductus arteriosus?
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abnormal circulation between aorta and pulmonary trunk
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what are the four anatomical components associated with Tetralogy of Fallot?
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ventricular septal defect, pulmonic stenosis, over-riding aorta, and right ventricular hypertrophy
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what is transposition of the great vessels?
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when the pulmonary trunk arises from the left ventricle and the aorta from the right ventricle.
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what is dextrocardia? People who suffer from dextrocardia also usually suffer from what?
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when the primitive heart folds to the right instead of to the left; situs inversus
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