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184 Cards in this Set

  • Front
  • Back
Function of basal anglion in motor activity:
Getting proper initation of momvent
Axon of the upper motor neuron passes through:
corona radiata [telencephalon]
posterior limb and genu of internal capsule [telencephalon]
cerebral crus [midbrain]
longitudinal fascicles [pons]
pyramid [medulla]
Crossed fibers make :
lateral funiculus
Lateral corticospinal pathway controls:
predominantely distal limb muscle
motor nuclei receiving projection from both hemispheres – name + function:
-Superior part of facial nucleus (to orbicularis oculi muscle [blinking])
-Ambiguus nucleus (IX, X, XI) (to palate, pharynx and larynx [swallowing, repiration])
-Motor trigeminal n. (to mastication muscles [mastication])
Injury to upper motor neuron:
-muscle weakness or paresis
-muscle spasticity
-hyperactive muscle stretch reflex
-alteration of cutaneous reflex
–lack of plantar reflex and Babinski sign
Injury to lower motor neuron:
-muscle weakness
-decrease of muscle tone,
-absence of stretch reflex
-muscles atrophy
Basal nuclei consist of:
Striatum, Pallidum,s ubthalamic nucleus, substantia nigra
Striatum =
caudate nucleus
lentiform nucleus =.
Putamen, Globus pallidus
Neuronal loop of basal ganglia:
Cortex – Putamen(striatum)- Lateral globus pallidus(Pallidum) – thalamus (VA, VL) – cortec
Neuronal loop of oculomotor:
Cortex -> caudate body -> SNr + GPi -> VA MD thalamus -> FEF(cortex)
Basal nuclei work through which strucutres:
thalamic nuclei (VA) + cerebral cortex (BA 6)
Neuronal loop of limbic:
Cortex -> ventral striatum -> ventral pallidum -> thalamus MD -> prefrontal (cortex)
Dorsal striatum (striatum) receives what from where?:
efferents from neocortex,
ventral striatum (accumbens nucleus) from where?
from limbic lobe
Limbic loop is strongly associated With:
emotional and motivational aspect of behaviour
Striatum consist of:
matrix, striosomes
In limbic loop – which part is under the influence of DA + source:
Ventral striatum from VTA
Striatum matrix –connections:
-from the entire cortex -from the thalamus
Striatum striosoms –connections:
-from prefrontal (limbic) cortex
GABA/Enk – from where to where?
Striatum to external globus pallidus
GABA/P – from where to where?
Striatum to internal globus pallidus
Direct pathway acts to:
facilitate desired voluntary movement,
non-direct pathway acts to:
inhibit unwanted competing movements.
dopaminergic neurons location:
either substantia nigra (compact part -SNc) or ventral tegmental area (VTA)
Except GABA the Basal motor loop is influenced by:
cholinergic neurons of striatum
Injury to basal ganglia loops:
- increased or decreased muscle tone (hyper-i hypotonia)
-dyskinesia (hyper-or hypokinesia)
-characteristic resting tremor
-for limbic loop -correlation with schizophrenia, addictive behaviours
Among the brainstem centers controlling motor activity there are:
-Red nucleus
-Vestibular nuclei
-Tectum
-Reticular formation
Brainstem centers send projection upon the spinal cord :
-rubrospinal
-vestibulospinal
-reticulospina
l –tectospinal
Brainstem centers send projection descend mainly in:
anterior funiculus
Brainstem descending tracts -voluntary movements:
-anterior and lateral corticospinal
Brainstem descending tracts -somato-visuo-acousticcoordination:
tectospinal
Cerebellum – pathway to motor neurons:
Cerebellar cortex-> Deep cerebellar nucleus -> Brainstem or Cortex (via VL thalamus) -> Motor neuron
Functional division of the cerebellar cortex –based on connection’s pattern:
-flocculonodular lobe vermis and paravermal zone
-lateral part of hemisphere
Cerebellar nuclei:
fastigial interposed (globose and emboliform) dentate
Injury to cerebellum:
- motor ataxia: difficulty maintaining posture or balance
+intention tremor
+ dysmetria (inability to stop movement in proper place)
comprising 40-50% of brain mass – what:
Cerebral cortex
Limbic is in which cortex?
Archicortex
“olfactory system” is in which cortex:
Paleocortex
Hippocampus + Dentate gyrus – which cortex:
Archicortex
Neocortex layers:
Molecular
II. external granular
III. external pyramidal
IV. internal granular
V. internal pyramidal
VI. Multiform
Cellular composition of Neocortex:
Two chief neuronal types:
Pyramidal and stellate +
horizontal (I) and Martinotti cells (VI)
outer and inner Baillarger’s bands are found where?
Neocortex
name/type of afferent “bundles” from thalamus to cortex?
Corticopetal
corticofungal are what + go where?
Efferent “signals” from cortex to: Striatum,brainstem or spinal cord
cortex - Presence and width of granular layer underlines the division into:
Agranular Eugranular Hypergranular
Heterotypical cortex include what:
motor/sensory areas
Homotypical cortex include what:
association areas
First-order motor cortex – location + ba:
precentral gyrus and anterior portion of paracentral lobule -BA 4:
supplementary motor area – location + ba:
medial surface of superior frontal gyrus -BA 6
Premotor cortex – location + ba:
posterior portions of superior, middle and inferior frontal gyri -BA 6
Frontal eye field (FEF) –location + ba:
mid-part of middle frontal gyrus -BA 8
Primary somatosensory cortex –location + ba:
postcentral gyrus and posterior portion of paracentral lobule -BA 3, 1, 2
First-order somatosensory cortex get into from where?
-general sensation from the contralateral half of the body
Gustatory area ba?
BA 43
visuomotor coordination – do where?
Sensory association area
Sensory association area location + ba:
superior and inferior parietal lobule -BA 5,7,39,40
stereognosis is what?
ability to recognize objects held in hand
stereognosis – which area makes it possible?
Sensory association area
Visual association cortex – location + ba:
BA 18, 19, visual areas in temporal and parietal cortex
Visual association cortex-receives stimuli from which BA?
BA 17
reflexive movement of the eye – do where?
Visual association cortex
First-order visual cortex ba?
BA 17
First-order auditory cortex – location + ba:
transverse temporal [Heschl’s] gyri -BA 41,42):
Second order auditory areas location + ba?
BA 22 posterior part of superior temporal gyrus
Second order auditory areas do what:
Interpretation of sounds (differentiation into speech and non-speech)
+ integration of auditory input with other sensory information
Temporal association cortex do what:
recognitionand identification of highlyprocessed + sensory informations (face recognition) –fusiform gyrus
Temporo-parieto-occipital cortex function:
-integration of information from unimodal association cortices
Prefrontal cortex ba:
BA 9, 10, 11, 12
Prefrontal cortex location:
frontal pole,
most part of superior,
middle and inferior frontal gyri, orbital gyri
Agnosia?
failure to recognize and understand the previously known symbolic significance of sensory stimuli despite the intactness of sensory pathways and the absence of mental disorders and dementia
this specialization is more highly conserved than left hemisphere dominance for language?
SPATIAL ATTENTION
Apraxia ?
–inability to execute learned voluntary function without any detectable motor or sensory deficits
Prefrontal cortex divided into:
orbitofrontal cortex and dorsolateral prefrontal cortex
Heard speech -chief comprehension area – name + ba?
–BA 22 -Wernicke’s area
Spoken language -chief production area – name + ba:
BA 44,45-Broca’s area
Language areas are bidirectionally connected by:
arcuate fasciculus
Aphasia?
–diminished or abolished ability to comprehend and/or produce language
Area outside of BBB in rhomboid fossa?
area postrema
Area in rhomboid fossa that makes NA:
locus coeruleus
Brainstem general division:
-ventral part
-tegmentum
-tectum (for midbrain only)
Ambiguous nucl. Is for which CN?
CN IX, CN X, CN XI
Solitary N. is for which CN?
CN VII, IX, X
Supplementary motor structures of the brainstem:
substantia nigra (basal nuclei),
inferior olivary nucleus,
red nucleus (cerebellum)
dorsal longitudinal fascicle – descending or ascending – do what?
descending – connecting autonomic system centers of: hypothalamus brainstem spinal cord
Main ascending pathways - From spinal cord to cerebrum:
spinal lemniscus medial lemniscus
Main ascending pathways - From cranial nerve nuclei to cerebrum:
lateral lemniscus - trigeminal lemniscus
Medial longitudinal fascicle function:
coordinating eye, head and neck Movements
reticular formation extends inferior to:
to intermediate gray mater of the spinal cord
reticular formation extends superior to:
to intralaminar and midline nuclei of the thalamus
reticular formation – parts + nuclei:
median part –raphes nuclei
medial part –gigantocellular nuclei
lateral part –parvocellular nuclei
Reticular formation lateral part function:
Internal environment:
circulatory system,
alimentary system,
respiratory system
genital systems
reticular formation medial part function:
motor functions control,
sleep and wakefulness regulation.
state of consciousness,
pain modulation,
cortical excitability (ARAS)
reticular formation medial part (midbrain) gets input from:
Spinal cord(spinoreticular) +brainstem
which structures come from Epithalamus:
habenula, medullary stria, pinealbody
which structures come from Ventral thalamus:
Reticularnucleus subthalamicnucleus globus pallidus
Thalamic functional subdivision into nuclei of – name + function:
unimodal cortical projection
(motor, somatosensory, visual, auditory, limbic)
-polymodal cortical projection
(association cortex)
-other projections
(including non-cortical)
Thalamic syndrome:
-sensory disturbance
-movment disorders
-severe pain
Hypothalamus Chief roles:
1. Control of regulatory processes for maintaining body internal environment within narrow physiological range (homeostasis)
2. Executive center for limbic system (expressing emotions)
3. Control of instinctive (e.g. sexual) behaviour
4. Control of circadian rhythm and sleep-wake cycle
Hypothalamus Humoral output – direct and indirect system + target:
magnocellular system (direct)-> posterior lobe of hypophysis.

parvicellular system (non-direct) -> portal system of median eminence
Encephalon is made up by:
cerebrum + brainstem
Cerebrum is made up by:
telencephalon
(Cerebral hemispheres, Telencephalon impair)
Diencephalon
Function of cerebellum in motor activity:,
Sensory motor coordination
Submental triangle is bounded by:.
the right and left anterior bellies of the digastric muscles
Submandibular triangle is bounded by:
inferior border of the mandible and the anterior and posterior bellies of the digastric muscle.
Carotid triangle is bounded by:
the superior belly of the omohyoid,
the posterior belly of the digastric,
and the anterior border of the SCM
Sternocleidomastoid region content(more then SCM):
superior part of the external jugular vein;
greater auricular nerve;
transverse cervical nerve
Occipital Triangle content:Part of external jugular vein
spinal accessory nerve; trunks of brachial plexus
Omoclavicular triangle content:
Subclavian artery (third part);
part of subclavian vein (sometimes);
suprascapular artery; supraclavicular lymph nodes
Carotid triangle content:
Common carotid artery and its branches;'
internal jugular vein and its tributaries;
vagus nerve;
external carotid artery and some of its branches;
hypoglossal nerve and superior root of ansa cervicalis;
spinal accessory nerve; thyroid gland, larynx; pharynx; deep cervical lymph nodes; branches of cervical plexus
Muscular triangle content:
Sternothyroid and sternohyoid muscles; thyroid and parathyroid glands
facial nerve go via which foramens + which spaces:
->Internal acusticus meatus ->Facial canal ->Stylomastoid foramen -> retromandibular fossa
Which muscle stretches vocal ligament?
Cricothyroid
Which muscle relaxes vocal ligament?
Thyroarytenoid
Which muscles is used for phonation?
Transverse arytenoid
Which muscles is used for whispering?
Lateral cricoArytenoid
Oculomotor Superior branch do what?
It supplies the Superior rectus and Levator palpebrae superioris.
Oculomotor inferior branch do what?
medial rectus,the inferior rectus. + parasymp till ciliary ganglion
Superior Oblique (SO) movments:
, Abducts,depresses, and rotates eyeball medially (intorsion)
Inferior Oblique (IO) movments:
Abducts,elevates, and rotates eyeball laterally (extorsion)
Convergent strabismus can be due to:
,Injury to abducens nerve -> paralysis of the lateral rectus muscle
Levator Palpebrae superioris movments:
Elevates Superior eyelid
Superior rectus (SR) movments:
Elevates,adducts, and rotates eyeball medially (intorsion)
Inferior rectus (IR) movments:
Depresses,adducts, and rotates eyeball laterally (extorsion)
Pharyngeal plexus innvervates muscles of the pharynx and soft palate except::
the stylopharyngeus (supplied by CN IX) and the tensor veli palatini (supplied by CN V 3)
The lateral cervical Region content – vessels:
-external jugular vein,
-transverse cervical and suprascapular vessels,
'-subclavian vein (occasionally) and artery,
Prevertebral space content:
It includes the prevertebral muscles (longus colli and longus capitis), vertebral artery, vertebral vein, scalene muscles, phrenic nerve and part of the brachial plexus.
Parapharyngeal space content nerves:
, -CN IX, CN X, CN XI, CN XII
Otic ganglion gets Sympathetic Fibers from:
Plexus on middle meningeal artery
thyrohyoid muscle innervated by?
is innervated by C1 via the hypoglossal nerve.
Parapharyngeal space content vessels:
-internal carotid a.
-internal jugular v.
Lateral cricoarytenoid function:
Adducts vocal folds (interligamentous portion)
Which muscles of the Larynx are the Tensor and relexor + function:
Tensor: cricothyroid
Relaxer: thyro-arytenoid
- To adjust the pitch: change of dimensions (length, thickness) change of tension
tensor veli palatine is supplied by:
Nerve to medial pterygoid (CN V3 via otic ganglion)
Posterior cricoarytenoid function:
Abducts vocal folds
Which structures go through gap between cranial base and superior pharyngeal constrictor:
pharyngotympanic tube -levator veli palatini m.
Which structures go through gap between superior and middle pharyngeal constrictors:
stylopharyngeus m. -CN IX -stylohyoid lig
The nerve supply of the posteroinferior half of the nasal mucosa is chiefly
from CN V2 ->nasopalatine nerve
the anterosuperior part of the nasal mucosa (both the septum and lateral wall) is innervated by:
, the anterior ethmoidal nerves, branches of CN V1
The ethmoidal sinuses are innervated by:
the anterior and posterior ethmoidal branches of the nasociliary nerves (CN V1).
Tympanic membrane landmarks:
anterior and posterior malleolar folds -malleolar prominence (<-lateral process) -malleolar stria (<-manubrium) -umbo of tympanic membrane
Tympanic cavity walls: medial::
labyrinthine wall
-separates form inner ear made by: -promontory (<-basal turn of cochlea)
-oval window (<-footplate of stapes and anular lig. of stapes)
-round window (<-secondary tympanic membrane)
-prominence of facial canal
Tympanic cavity walls: anterior:
carotid wall (separates from carotid canal) =Has opening for: -tympanic opening of pharyngotympanic tube -semicanal for tensor tympani m.
Tympanic cavity walls: inferior: Floor
jugular wall
Tympanic cavity walls: superior: Roof
, tegmental wall - formed by tegmen tympani)
tensor tympani muscle nerve:
CN. V3
stapedius muscle nerve:
CN VII
Tympanic cavity walls: posterior:
mastoid wall =Opening for: aditus to mastoid antrum and a pyramidal eminence (<.stapedius m.)
Lateral wall of orbit:
Zygomatic and greater wing of sphenoid
infratemporal fossa Content:
.-Lateral and medial pterygoid muscles .
-Maxillary artery. -otic ganglion
Pterygopalatine fossa content:
maxillary a.maxillary n. pterygopalatine ganglion
infratemporal fossa communicates with:
-Superolaterally : Temporal fossa via gap bounded by zygomatic arch
-Anteriorly -: Orbit via inferior orbital fissure -
Medially : pterygopalatine fossa via pterygomaxillary fissure
Superiorly: Middle cranial fossa via foramen ovale and foramen spinosum
-Posterior: parapharyngeal space and Retromandibular fossa
Cavernous sinus - drain through:
superior and inferior petrosal sinuses - emissary vein to the pterygoid plexuses
From cochlear nuclei axons project to(2):
Ipso/contralateral superior olivary nuclei Or nucleus of lateral lemniscus
Anterior and posterior cochlear nucleus receives input from:
the cochlear nerve (CN VIII).
Medial geniculate body receives input from + via?
Via brachium of inferior colliculus the nucleus of the inferior colliculus.
Medial geniculate body projects via + where:
, via the auditory radiation to the primary auditory cortex, the transverse gyri of Heschl
Superior olivary nucleus projects:
bilaterally to the lateral lemniscus. (both sides)
How do the singals go to inferior colliculus / via what:
Via lateral lemniscus
After inferior colliculus – the singals go where via?
Via brachium of inferior colliculus to -> medial geniculate nucleus
Lateral lemniscus projects to:
the nucleus of the inferior colliculus.
Lateral lemniscus receives input from(2):
receives input from the contralateral cochlear nuclei.
receives input from the superior olivary nuclei.
What can we find in retromandibular fossa?
Parotid gland
two small communicating sacs in the vestibule of the bony labyrinth =,
utricle and saccule
The semicircular ducts open into
:, the utricle
Papez circuit is invloved with what:,
Making long term memory

Memory consolidation is based upon long term potentiation phenomenon
(LTP)
Papez circuit patway:,
Hippocampus -> Mammillary body -> Anterior thalamic nucleus -> cingulate gyrus -> hippocampus
Kluver-Bucy syndrome due to? leads to?
(bilateral lesion or ablation of amygdala and uncus)

-loss of fear
-little emotional reaction to external stimuli
-sexual hyperactivity
-changes in behaviour –from aggressive to placid
Wernicke-Korsakoff syndrome: is due to? leads to?
(toxic effect of alcohol and associated thiamine deficiency)
-difficulties in remembering events after the disease’s onset
-difficulty in retaining newly acquired information
STRIATUM - do what in memory
-memory for habits, actions and outcomes
AMYGDALOID BODY do what in memory
-memory for emotions
-influences memory consolidation in other memory systems
GABA - Most important functions and regulated processes:
•motor function
•inhibition of epileptic activi
Glutamatergic system - Most important functions and regulated processes:
•learning and memory
•projecting neurons of the cerebral cortex
(neocortex, allocortex)
Cholinergic system - Most important functions and regulated processes:
•learning and memory
•consciousness and concentration
•motor control
Dopaminergic system - Most important functions and regulated processes:
•motor and cognitive control
•reward behavior, pleasurable sensations, „feeling good”
Noradrenergic system - Most important functions and regulated processes:
•emotions and mood regulation
excitation and mobilizing action (attention and cortical arousal)
anxiety
•circadian rhythms control
sleep-wake cycle
•circulatory system control
pulse and blood pressure regulation
body of third neuons in Ascending tracts are located?,
VPL thalamic nucleus
which patwhay for epicritic sensation?,
Posteriorfuniculus-
Dorsal column-medial lemniscus pathway
Anterior and lateral funiculi is used for:
Anterolateral system ->
protopathic sensation
begins 1-2 segments below the lesion (due to presence of collaterals in Lissauer tract
Which system?
Lateral spinothalamic tract in the spinal cord:
(protopathic sensation)

Den andra slutar direct below the lesion
epicritic sensation for head go where?,
principal sensory nucleus of CN V
protopathic sensation for head go where?,
mainly spinal trigeminal nucleus
Dorsal (DSC) and ventral (VSC) spinocerebellar tracts provide to cerebellum:
-info from the lower limb
-info about tension of muscles (muscle spindles), and tendons (Golgi tendon organs)
allowing online control of movements’ execution